Search Results - "Krestinina, O."

Translocator Protein Is Involved in the Induction and Regulation of Mitochondrial Permeability Transition Pore Opening in C6 Glioma Cells by Baburina, Yu. L., Sotnikova, L. D., Krestinina, O. V.

“…Translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor (PBR), is a 18-kDa protein localized in the outer mitochondrial…”
Get full text

Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria by Azarashvili, T, Krestinina, O, Baburina, Yu, Odinokova, I, Grachev, D, Papadopoulos, V, Akatov, V, Lemasters, J J, Reiser, G

“…Permeability of the mitochondrial outer membrane is determined by the activity of voltage-dependent anion channels (VDAC) which are regulated by many factors…”
Get full text

Melatonin Enhances the Effect of ABT-737 in Acute Monocytic Leukemia THP-1 Cells by Lomovsky, A. I., Baburina, Y. L., Fadeev, R. S., Kobyakova, M. I., Lomovskaya, Ya. V., Krestinin, R. R., Sotnikova, L. D., Krestinina, O. V.

“…Melatonin ( N -acetyl-5-methoxytryptamine, MEL) is a hormone synthesized by the pineal gland. Due to its oncostatic effect, it can be considered as an…”
Get full text

Melatonin Enhances the Effect of ABT-737 in Acute Monocytic Leukemia THP-1 Cells by Lomovsky, A I, Baburina, Y L, Fadeev, R S, Kobyakova, M I, Lomovskaya, Ya V, Krestinin, R R, Sotnikova, L D, Krestinina, O V

“…Melatonin (N-acetyl-5-methoxytryptamine, MEL) is a hormone synthesized by the pineal gland. Due to its oncostatic effect, it can be considered as an antitumor…”
Get more information

Melatonin Enhances the Chemotherapeutic Effect of Cytarabin in HL-60 Cells by Lomovsky, A. I., Baburina, Yu. L., Kobyakova, M. I., Fadeev, R. S., Akatov, V. S., Krestinina, O. V.

“…The combined effect of melatonin and cytarabin at low concentration on the cells of acute promyelocytic leukemia HL-60 was studied. It has been shown that the…”
Get full text

Effect of peripheral benzodiazepine receptor (PBR/TSPO) ligands on opening of Ca²⁺-induced pore and phosphorylation of 3.5-kDa polypeptide in rat brain mitochondria by Krestinina, O. V, Grachev, D. E, Odinokova, I. V, Reiser, G, Evtodienko, Yu. V, Azarashvili, T. S

“…The effect of nanomolar concentrations of PBR/TSPO ligands--Ro 5-4864, PK11195, and PPIX--on Ca²⁺-induced permeability transition pore (PTP) opening in…”
Get full text

Detection of Protein Kinase A and C Target Proteins in Rat Brain Mitochondria by Krestinina, O. V., Odinokova, I. V., Baburina, Yu. L., Azarashvili, T. S.

“…Phosphorylation of some membrane-bound proteins in the mitochondria of rat liver and brain is regulated by Ca 2+ and cAMP acting as secondary messengers. These…”
Get full text

Operation of the Permeability Transition Pore in Rat Heart Mitochondria in Aging by Odinokova, I. V., Baburina, Yu. L., Kruglov, A. G., Santalova, I. M., Azarashvili, T. S., Krestinina, O. V.

“…The functioning of the mitochondrial permeability transition pore (mPTP) is involved in the mechanism of programmed cell death and mitochondrial dysfunction…”
Get full text

Interaction of myelin basic protein and 2′,3′-cyclic nucleotide phosphodiesterase with mitochondria by Baburina, Yu. L., Gordeeva, A. E., Moshkov, D. A., Krestinina, O. V., Azarashvili, A. A., Odinokova, I. V., Azarashvili, T. S.

“…The content and distribution of myelin basic protein (MBP) isoforms (17 and 21.5 kDa) as well as 2′,3′-cyclic nucleotide-3′-phosphodiesterase (CNPase) were…”
Get full text

High-affinity peripheral benzodiazepine receptor ligand, PK11195, regulates protein phosphorylation in rat brain mitochondria under control of Ca(2+) by Azarashvili, T, Krestinina, O, Yurkov, I, Evtodienko, Y, Reiser, G

“…The effects of PK11195, a high-affinity peripheral benzodiazepine receptor (PBR) ligand, on protein phosphorylation in isolated purified rat brain mitochondria…”
Get full text

Effect of melatonin on stress-induced opening of non-selective pore in mitochondria from brain of young and old rats by Krestinina, O. V., Baburina, Yu. L., Azarashvili, T. S.

“…Oxidative stress is the major factor affecting different organs during aging. Mitochondria are considered to be a source of endogenous oxidants, concentrations…”
Get full text

High‐affinity peripheral benzodiazepine receptor ligand, PK11195, regulates protein phosphorylation in rat brain mitochondria under control of Ca2 by Azarashvili, T., Krestinina, O., Yurkov, I., Evtodienko, Y., Reiser, G.

“…The effects of PK11195, a high‐affinity peripheral benzodiazepine receptor (PBR) ligand, on protein phosphorylation in isolated purified rat brain mitochondria…”
Get full text

Age-related effect of melatonin on permeability transition pore opening in rat brain mitochondria by Krestinina, O. V., Odinokova, I. V., Baburina, Yu. L., Azarashvili, T. S.

“…Aging is accompanied by mitochondrial dysfunction related with lowering of the respiratory complex activity and decrease of ATP synthesis, as well as by an…”
Get full text

Astaxanthin Prevents Dysregulation of Mitochondrial Dynamics in Rat Brain Mitochondria Induced by Isoproterenol by Krestinin, R. R., Baburina, Y. L., Odinokova, I. V., Sotnikova, L. D., Krestinina, O. V.

“…Mitochondria are involved in diseases of various etiologies. The use of drugs aimed at improving the functional state of mitochondria may be a promising…”
Get full text

The Combined Effects of Melatonin and Diethyldithiocarbamate on Mouse N1E-115 Neuroblastoma Cells (Clone C-1300) by Myakisheva, S. N., Baburina, Y. L., Kobyakova, M. I., Krestinin, R. R., Sotnikova, L. D., Krestinina, O. V.

“…The effects of sodium diethyldithiocarbamate, melatonin, and their combined use on proliferative activity, changes in cytosolic Ca 2+ , membrane potential, and…”
Get full text

The Effect of Astaxanthin on the Functional State of Brain Mitochondria in Rats with Heart Failure by Krestinin, R. R., Baburina, Yu. L., Odinokova, I. V., Sotnikova, L. D., Krestinina, O. V.

“…The effect of astaxanthin on the functional state of brain mitochondria in rats with heart failure was studied. Heart failure was achieved by administering…”
Get full text

Role of phosphorylation of porin (VDAC) in regulation of mitochondrial outer membrane under normal conditions and alcohol intoxication by Azarashvili, T. S., Odinokova, I. V., Krestinina, O. V., Baburina, Y. L., Grachev, D. E., Teplova, V. V., Holmuhamedov, E. L.

“…The present work is an overview of the factors regulating permeability of the outer membrane of mitochondria and the state of the channels formed by porin…”
Get full text

Effect of Ro 5-4864 and PK11195 on protein phosphorylation in mitochondria isolated from primary cultures of rat astrocytes by Grachev, D. E., Krestinina, O. V., Baburina, Y. L., Reiser, G., Azarashvili, T. S.

“…Astrocytes are the most numerous cell type within the central nervous system. Earlier, high-affinity binding sites for [ 3 H]PK 11195 and [ 3 H]Ro 5-4864 with…”
Get full text

Age-dependent changes of mitochondrial functions in Ca2+-induced opening of permeability transition pore by Krestinina, O. V., Kruglov, A. G., Grachev, D. E., Baburina, Yu. L., Evtodienko, Yu. V., Moshkov, D. A., Santalova, I. M., Azarashvili, T. S.

“…Mitochondria are intracellular organelles, which provide cells with energy and participate in multiple processes of cell vital functions. Within one of the…”
Get full text

Effect of erastin and G3139 on rat liver mitochondria in chronic alcoholic intoxication by Baburina, Yu L, Zvyagina, A I, Odinokova, I V, Krestinina, O V

“…The effect of modulators of VDAC channels - G3139 and erastin on the mitochondrial permeability transition pore (mPTP) functioning and changes in the content…”
Get more information