Search Results - "Kresse, H"
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Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples
Published in PloS one (17-05-2018)“…Nucleic acid material of adequate quality is crucial for successful high-throughput sequencing (HTS) analysis. DNA and RNA isolated from archival FFPE material…”
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Functional characterisation of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes
Published in British journal of cancer (15-10-2013)“…Background: Osteosarcoma is the most common primary malignant bone tumour, predominantly affecting children and adolescents. Cancer cell line models are…”
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3
Modulation of the osteosarcoma expression phenotype by microRNAs
Published in PloS one (25-10-2012)“…Osteosarcomas are the most common primary malignant tumors of bone and show multiple and complex genomic aberrations. miRNAs are non-coding RNAs capable of…”
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4
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma
Published in PloS one (07-11-2012)“…Osteosarcomas are the most common non-haematological primary malignant tumours of bone, and all conventional osteosarcomas are high-grade tumours showing…”
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5
miR-486-5p expression is regulated by DNA methylation in osteosarcoma
Published in BMC genomics (17-02-2022)“…Osteosarcoma is the most common primary malignant tumour of bone occurring in children and young adolescents and is characterised by complex genetic and…”
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Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data
Published in Genes chromosomes & cancer (01-07-2012)“…High‐grade osteosarcoma is a tumor with a complex genomic profile, occurring primarily in adolescents with a second peak at middle age. The extensive genomic…”
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Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood
Published in Clinical epigenetics (14-09-2023)“…Abstract Background DNA methylation biomarkers in circulating cell-free DNA (cfDNA) have great clinical potential for cancer management. Most methods for DNA…”
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8
Molecular characterization of commonly used cell lines for bone tumor research: A trans-European EuroBoNet effort
Published in Genes chromosomes & cancer (01-01-2010)“…Usage of cancer cell lines has repeatedly generated conflicting results provoked by differences among subclones or contamination with mycoplasm or other…”
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Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations
Published in Cancer (15-01-2012)“…BACKGROUND: Human tumors transplanted into immunodeficient mice (xenografts) are good preclinical models, and it is important to identify possible systematic…”
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10
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
Published in Blood (02-09-2010)“…Our aim was to examine the genetics of clonal evolution in follicular lymphoma (FL) and to identify genetic alterations associated with disease progression. A…”
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LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization
Published in Genes chromosomes & cancer (01-08-2009)“…Osteosarcomas are the most common primary malignant tumor of bone, and almost all conventional osteosarcomas are high‐grade tumors with complex karyotypes. We…”
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Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas
Published in Cancer research (Chicago, Ill.) (15-09-2006)“…Leiomyosarcomas are spindle cell tumors showing smooth muscle differentiation. Until recently, most gastrointestinal stromal tumors (GIST) were also classified…”
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13
Structural investigation of chondroitin/dermatan sulfate oligosaccharides from human skin fibroblast decorin
Published in Glycobiology (Oxford) (01-11-2003)“…Hybrid chondroitin/dermatan sulfate (CS/DS) glycosaminoglycan chains, derived from decorin secreted by human skin fibroblasts, were shown to interact with…”
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14
mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts
Published in BMC medical genomics (20-09-2011)“…Conventional high-grade osteosarcoma is a primary malignant bone tumor, which is most prevalent in adolescence. Survival rates of osteosarcoma patients have…”
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15
New hockey stick compounds with a lateral methyl group showing nematic, synclinic and anticlinic smectic C phases
Published in Liquid crystals (01-09-2011)“…New hockey stick-shaped mesogens with a lateral methyl group inserted between the m-alkyloxy-chain and the azomethine connecting group,…”
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DNA copy number changes in human malignant fibrous histiocytomas by array comparative genomic hybridisation
Published in PloS one (09-11-2010)“…Malignant fibrous histiocytomas (MFHs), or undifferentiated pleomorphic sarcomas, are in general high-grade tumours with extensive chromosomal aberrations. In…”
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A tissue microarray study of osteosarcoma: histopathologic and immunohistochemical validation of xenotransplanted tumors as preclinical models
Published in Applied immunohistochemistry & molecular morphology (01-10-2010)“…Osteosarcomas (OS) are aggressive neoplasms with a wide range of morphologic patterns. OS cases (primary and xenotransplanted) with paraffin blocks available…”
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Global Gene Expression Profiling of Human Osteosarcomas Reveals Metastasis-Associated Chemokine Pattern
Published in Sarcoma (2012)“…Global gene expression analysis was performed on a panel of 23 osteosarcoma samples of primary and metastatic origin using the Applied Biosystems Gene…”
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DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH
Published in Molecular cancer (03-06-2008)“…Malignant peripheral nerve sheath tumors (MPNSTs) are rare and highly aggressive soft tissue tumors showing complex chromosomal aberrations. In order to…”
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M-CGH: analysing microarray-based CGH experiments
Published in BMC bioinformatics (09-06-2004)“…Microarray-based comparative genomic hybridisation (array CGH) is a technique by which variation in relative copy numbers between two genomes can be analysed…”
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