Search Results - "Kress, T"
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Impairment of paravascular clearance pathways in the aging brain
Published in Annals of neurology (01-12-2014)“…Objective In the brain, protein waste removal is partly performed by paravascular pathways that facilitate convective exchange of water and soluble contents…”
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2
Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections
Published in Nature neuroscience (01-02-2019)“…Analysis of entire transparent rodent bodies after clearing could provide holistic biological information in health and disease, but reliable imaging and…”
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3
A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone
Published in The Journal of neuroscience (26-08-2015)“…Microglia are involved in synaptic pruning both in development and in the mature CNS. In this study, we investigated whether microglia might further contribute…”
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Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer
Published in Journal of translational medicine (01-05-2013)“…Neurodegenerative diseases such as Alzheimer's are associated with the aggregation of endogenous peptides and proteins that contribute to neuronal dysfunction…”
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Neuronal transgene expression in dominant-negative SNARE mice
Published in The Journal of neuroscience (10-12-2014)“…Experimental advances in the study of neuroglia signaling have been greatly accelerated by the generation of transgenic mouse models. In particular, an elegant…”
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Simulated magnetopause losses and Van Allen Probe flux dropouts
Published in Geophysical research letters (28-02-2014)“…Three radiation belt flux dropout events seen by the Relativistic Electron Proton Telescope soon after launch of the Van Allen Probes in 2012 (Baker et al.,…”
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Simulated Trapping of Solar Energetic Protons for the 8–10 March 2012 Geomagnetic Storm: Impact on Inner Zone Protons as Measured by Van Allen Probes
Published in Journal of geophysical research. Space physics (01-02-2023)“…Solar energetic protons (SEPs) have been shown to contribute significantly to the inner zone trapped proton population for energies <100 MeV and L > 1.3…”
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Modeling CME-shock-driven storms in 2012-2013: MHD test particle simulations
Published in Journal of geophysical research. Space physics (01-02-2015)“…The Van Allen Probes spacecraft have provided detailed observations of the energetic particles and fields environment for coronal mass ejection…”
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9
Direct observation of the CRAND proton radiation belt source
Published in Journal of geophysical research. Space physics (01-12-2013)“…Observations of geomagnetically trapped 27–45 MeV protons following the November 2003 magnetic storm show a gradual intensity rise that is interpreted as a…”
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Observations of the inner radiation belt: CRAND and trapped solar protons
Published in Journal of geophysical research. Space physics (01-08-2014)“…Measurements of inner radiation belt protons have been made by the Van Allen Probes Relativistic Electron‐Proton Telescopes as a function of kinetic energy (24…”
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Global storm time depletion of the outer electron belt
Published in Journal of geophysical research. Space physics (01-04-2015)“…The outer radiation belt consists of relativistic (>0.5 MeV) electrons trapped on closed trajectories around Earth where the magnetic field is nearly dipolar…”
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12
Utilizing machine learning algorithms to predict subject genetic mutation class from in silico models of neuronal networks
Published in BMC medical informatics and decision making (09-11-2022)“…Abstract Background Epilepsy is the fourth-most common neurological disorder, affecting an estimated 50 million patients globally. Nearly 40% of patients have…”
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13
Injection and loss of inner radiation belt protons during solar proton events and magnetic storms
Published in Journal of Geophysical Research: Space Physics (01-08-2010)“…A survey of 27 to 45 MeV proton measurements from the HEO‐3 satellite during the years 1998 through 2005 has been taken to describe variability in the outer…”
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14
The role of drift orbit bifurcations in energization and loss of electrons in the outer radiation belt
Published in Journal of Geophysical Research: Space Physics (01-09-2011)“…Radiation levels in Earth's outer electron belt (L ≳ 2.5) vary by orders of magnitude on the time scales ranging from minutes to days. Multiple acceleration…”
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Simulations of inner radiation belt proton loss during geomagnetic storms
Published in Journal of geophysical research. Space physics (01-11-2015)“…The loss of protons in the outer part of the inner radiation belt (L = 2 to 3) during the 6 April 2000 solar energetic particles event has been investigated…”
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Hemoperfusion with Seraph 100 Microbind Affinity Blood Filter Unlikely to Require Increased Antibiotic Dosing: A Simulations Study Using a Pharmacokinetic/Pharmacodynamic Approach
Published in Blood purification (2023)“…The Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100) is a hemoperfusion device that can remove pathogens from central circulation. However, the effect…”
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Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users
Published in Journal of xenobiotics (10-05-2023)“…Selective Androgen Receptor Modulators (SARMs) are not FDA approved, and obtaining SARMs for personal use is illegal. Nevertheless, SARM use is increasingly…”
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Systematic Review and Meta-Analysis of the Effect of Loop Diuretics on Antibiotic Pharmacokinetics
Published in Pharmaceutics (05-05-2023)“…Loop diuretics and antibiotics are commonly co-prescribed across many clinical care settings. Loop diuretics may alter antibiotic pharmacokinetics (PK) via…”
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Plerixafor for pathogen‐agnostic treatment in murine thigh infection and zebrafish sepsis
Published in Clinical and translational science (01-07-2024)“…Plerixafor is a CXCR4 antagonist approved in 2008 by the FDA for hematopoietic stem cell collection. Subsequently, plerixafor has shown promise as a potential…”
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Modeling geomagnetic cutoffs for space weather applications
Published in Journal of geophysical research. Space physics (01-07-2015)“…Access of solar and galactic cosmic rays to the Earth's magnetosphere is quantified in terms of geomagnetic cutoff rigidity. Numerically computed grids of…”
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