Search Results - "Kresovich, Jacob K."

Air pollution, particulate matter composition and methylation-based biologic age by White, Alexandra J., Kresovich, Jacob K., Keller, Joshua P., Xu, Zongli, Kaufman, Joel D., Weinberg, Clarice R., Taylor, Jack A., Sandler, Dale P.

“…Epigenetic age, as defined by DNA methylation, may be influenced by air pollution exposure. To evaluate the relationship between NO2, particulate matter (PM),…”
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Peripheral Immune Cell Composition is Altered in Women Before and After a Hypertension Diagnosis by Kresovich, Jacob K., Xu, Zongli, O’Brien, Katie M., Parks, Christine G., Weinberg, Clarice R., Sandler, Dale P., Taylor, Jack A.

“…The development and consequences of hypertension involve multiple biological systems that may include changes in immune profiles. Whether hypertension is…”
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Metallic air pollutants and breast cancer heterogeneity by Kresovich, Jacob K., Erdal, Serap, Chen, Hua Yun, Gann, Peter H., Argos, Maria, Rauscher, Garth H.

“…Emerging evidence suggests airborne metals may be associated with breast cancer risk. However, breast cancer is heterogenous and associations with heavy metals…”
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Reproduction, DNA methylation and biological age by Kresovich, Jacob K, Harmon, Quaker E, Xu, Zongli, Nichols, Hazel B, Sandler, Dale P, Taylor, Jack A

“…Abstract STUDY QUESTION Are reproductive characteristics associated with genome-wide DNA methylation and epigenetic age? SUMMARY ANSWER Our data suggest that…”
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Air pollution and epigenetic aging among Black and White women in the US by Koenigsberg, Sarah H., Chang, Che-Jung, Ish, Jennifer, Xu, Zongli, Kresovich, Jacob K., Lawrence, Kaitlyn G., Kaufman, Joel D., Sandler, Dale P., Taylor, Jack A., White, Alexandra J.

“…[Display omitted] •Novel findings of air pollution and DNA methylation patterns in Black women.•Black women had higher exposure to NO2 and PM than non-Hispanic…”
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Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation by Rauscher, Garth H, Kresovich, Jacob K, Poulin, Matthew, Yan, Liying, Macias, Virgilia, Mahmoud, Abeer M, Al-Alem, Umaima, Kajdacsy-Balla, Andre, Wiley, Elizabeth L, Tonetti, Debra, Ehrlich, Melanie

“…Breast cancer formation is associated with frequent changes in DNA methylation but the extent of very early alterations in DNA methylation and the biological…”
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Blood DNA methylation profiles improve breast cancer prediction by Kresovich, Jacob K., Xu, Zongli, O’Brien, Katie M., Shi, Min, Weinberg, Clarice R., Sandler, Dale P., Taylor, Jack A.

“…Although blood DNA methylation (DNAm) profiles are reported to be associated with breast cancer incidence, they have not been widely used in breast cancer risk…”
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Blood pressure and expression of microRNAs in whole blood by Zhang, Zhou, Joyce, Brian Thomas, Kresovich, Jacob K, Zheng, Yinan, Zhong, Jia, Patel, Ruchi, Zhang, Wei, Liu, Lei, Dou, Chang, McCracken, John P, Díaz, Anaité, Motta, Valeria, Sanchez-Guerra, Marco, Bian, Shurui, Bertazzi, Pier Alberto, Schwartz, Joel, Baccarelli, Andrea A, Wang, Sheng, Hou, Lifang

“…Blood pressure (BP) is a complex, multifactorial clinical outcome driven by genetic susceptibility, behavioral choices, and environmental factors. Many…”
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Epigenome‐wide association study of prostate cancer in African American men identified differentially methylated genes by Berglund, Anders, Yamoah, Kosj, Eschrich, Steven A., Falahat, Rana, Mulé, James J., Kim, Sungjune, Matta, Jaime, Dutil, Julie, Ruiz‐Deya, Gilberto, Ortiz Sanchez, Carmen, Wang, Liang, Park, Hyun, Banerjee, Hirendra N., Lotan, Tamara, Barry, Kathryn Hughes, Putney, Ryan M., Kim, Seung Joon, Gwede, Clement, Kresovich, Jacob K., Kim, Youngchul, Lin, Hui‐Yi, Dhillon, Jasreman, Chakrabarti, Ratna, Park, Jong Y.

“…Introduction Men with African ancestry have the highest incidence and mortality rates of prostate cancer (PCa) worldwide. Methods This study aimed to identify…”
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Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects? by Kirkbride, James B, Susser, Ezra, Kundakovic, Marija, Kresovich, Jacob K, Davey Smith, George, Relton, Caroline L

“…We posit that maternal prenatal nutrition can influence offspring schizophrenia risk via epigenetic effects. In this article, we consider evidence that…”
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Low Serum Klotho Associated With All-cause Mortality Among a Nationally Representative Sample of American Adults by Kresovich, Jacob K, Bulka, Catherine M

“…Abstract α-Klotho (klotho) is a protein involved in suppressing oxidative stress and inflammation. In animal models, it is reported to underlie numerous aging…”
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Cord blood DNA methylation and adiposity measures in early and mid-childhood by Kresovich, Jacob K, Zheng, Yinan, Cardenas, Andres, Joyce, Brian T, Rifas-Shiman, Sheryl L, Oken, Emily, Gillman, Matthew W, Hivert, Marie-France, Baccarelli, Andrea A, Hou, Lifang

“…Excess adiposity in childhood is associated with numerous adverse health outcomes. As this condition is difficult to treat once present, identification of risk…”
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Methylation-Based Biological Age and Breast Cancer Risk by Kresovich, Jacob K, Xu, Zongli, O’Brien, Katie M, Weinberg, Clarice R, Sandler, Dale P, Taylor, Jack A

“…Abstract Background Age is one of the strongest predictors of cancer, chronic disease, and mortality, but biological responses to aging differ among people…”
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Methylation-Based Biological Age and Hypertension Prevalence and Incidence by Kresovich, Jacob K., Sandler, Dale P., Taylor, Jack A.

“…Hypertension is common in older individuals and is a major risk factor for cardiovascular disease. Blood DNA methylation profiles have been used to derive…”
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methscore: a comprehensive R function for DNA methylation-based health predictors by Xu, Zongli, Niu, Liang, Kresovich, Jacob K, Taylor, Jack A

“…Abstract Motivation DNA methylation-based predictors of various biological metrics have been widely published and are becoming valuable tools in epidemiologic…”
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Associations of lead and cadmium with sex hormones in adult males by Kresovich, Jacob K., Argos, Maria, Turyk, Mary E.

“…Heavy metal exposures are ubiquitous in the environment and their relation to sex hormones is not well understood. This paper investigates the associations…”
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Shift work, DNA methylation and epigenetic age by White, Alexandra J, Kresovich, Jacob K, Xu, Zongli, Sandler, Dale P, Taylor, Jack A

“…Abstract Background Shift work has been associated with increased risk of age-related morbidity and mortality. Biological age, estimated using DNA methylation…”
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Healthy eating patterns and epigenetic measures of biological age by Kresovich, Jacob K, Park, Yong-Moon Mark, Keller, Jean A, Sandler, Dale P, Taylor, Jack A

“…Healthy eating is associated with lower risks of disease and mortality, but the mechanisms underlying these associations are unclear. Age is strongly related…”
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Associations of Body Composition and Physical Activity Level With Multiple Measures of Epigenetic Age Acceleration by Kresovich, Jacob K, Garval, Emma L, Martinez Lopez, Alexandra M, Xu, Zongli, Niehoff, Nicole M, White, Alexandra J, Sandler, Dale P, Taylor, Jack A

“…Epigenetic clocks use DNA methylation to estimate biological age. Whether body composition and physical activity are associated with these clocks is not well…”
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Changes in methylation-based aging in women who do and do not develop breast cancer by Kresovich, Jacob K, O’Brien, Katie M, Xu, Zongli, Weinberg, Clarice R, Sandler, Dale P, Taylor, Jack A

“…Abstract Background Breast cancer survivors have increased incidence of age-related diseases, suggesting that some survivors may experience faster biological…”
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