Search Results - "Kremsdorf, Dina"

Alternative splicing of viral transcripts: the dark side of HBV by Kremsdorf, Dina, Lekbaby, Bouchra, Bablon, Pierre, Sotty, Jules, Augustin, Jérémy, Schnuriger, Aurélie, Pol, Jonathan, Soussan, Patrick

“…Regulation of alternative splicing is one of the most efficient mechanisms to enlarge the proteomic diversity in eukaryotic organisms. Many viruses hijack the…”
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Hepatitis B virus X protein promotes DNA damage propagation through disruption of liver polyploidization and enhances hepatocellular carcinoma initiation by Ahodantin, James, Bou-Nader, Myriam, Cordier, Corinne, Mégret, Jérôme, Soussan, Patrick, Desdouets, Chantal, Kremsdorf, Dina

“…Hepatitis B virus X protein (HBx) contributes to Hepatitis B virus (HBV)-related liver cancer. However, its impact on hepatocyte proliferation and genomic…”
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Modeling hepatitis virus infections and treatment strategies in humanized mice by Kremsdorf, Dina, Strick-Marchand, Helene

“…•HBV, HCV, HDV/HBV and HEV infections can be modeled in humanized mice with chimeric livers.•Immune competent humanized mice infected with HBV or HCV mount…”
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C-terminal-truncated hepatitis B virus X protein enhances the development of diethylnitrosamine-induced hepatocellular carcinogenesis by Quetier, Ivan, Brezillon, Nicolas, Revaud, Julien, Ahodantin, James, DaSilva, Lucie, Soussan, Patrick, Kremsdorf, Dina

“…Hepatitis B virus X protein (HBx) is involved in the development of hepatocellular carcinoma (HCC). The HBx sequence is a preferential site of integration into…”
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Alternative splicing of Hepatitis B virus: a novel virus/host interaction altering liver immunity by Duriez, Marion, Mandouri, Yassmina, Lekbaby, Bouchra, Wang, Hualin, Schnuriger, Aurélie, Redelsperger, Francois, Guerrera, Chiara, Lefevre, Marine, Fauveau, Veronique, Ahodantin, James, Quetier, Ivan, Chhuon, Cerina, Gourari, Samir, Boissonas, Alexandre, Gill, Upkar, Kennedy, Patrick, Debzi, Nabil, Sitterlin, Delphine, Maini, Mala K, Kremsdorf, Dina, Soussan, Patrick

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Transdifferentiation of hepatocyte‐like cells from the human hepatoma HepaRG cell line through bipotent progenitor by Cerec, Virginie, Glaise, Denise, Garnier, Delphine, Morosan, Serban, Turlin, Bruno, Drenou, Bernard, Gripon, Philippe, Kremsdorf, Dina, Guguen‐Guillouzo, Christiane, Corlu, Anne

“…Hepatic tumors, exhibiting mature hepatocytes and undifferentiated cells merging with cholangiocyte and hepatocyte phenotypes, are frequently described. The…”
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Antiviral activity of Bay 41-4109 on hepatitis B virus in humanized Alb-uPA/SCID mice by Brezillon, Nicolas, Brunelle, Marie-Noëlle, Massinet, Hélène, Giang, Eric, Lamant, Céline, DaSilva, Lucie, Berissi, Sophie, Belghiti, Jacques, Hannoun, Laurent, Puerstinger, Gherard, Wimmer, Eva, Neyts, Johan, Hantz, Olivier, Soussan, Patrick, Morosan, Serban, Kremsdorf, Dina

“…Current treatments for HBV chronic carriers using interferon alpha or nucleoside analogues are not effective in all patients and may induce the emergence of…”
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Humanized mice for modeling human infectious disease: challenges, progress, and outlook by Legrand, Nicolas, Ploss, Alexander, Balling, Rudi, Becker, Pablo D, Borsotti, Chiara, Brezillon, Nicolas, Debarry, Jennifer, de Jong, Ype, Deng, Hongkui, Di Santo, James P, Eisenbarth, Stephanie, Eynon, Elizabeth, Flavell, Richard A, Guzman, Carlos A, Huntington, Nicholas D, Kremsdorf, Dina, Manns, Michael P, Manz, Markus G, Mention, Jean-Jacques, Ott, Michael, Rathinam, Chozhavendan, Rice, Charles M, Rongvaux, Anthony, Stevens, Sean, Spits, Hergen, Strick-Marchand, Hélène, Takizawa, Hitoshi, van Lent, Anja U, Wang, Chengyan, Weijer, Kees, Willinger, Tim, Ziegler, Patrick

“…Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths…”
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New animal models for hepatitis C viral infection and pathogenesis studies by Kremsdorf, Dina, Brezillon, Nicolas

“…Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma (HCC). In man, the pathobiological changes associated…”
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IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo by Huntington, Nicholas D., Alves, Nuno L., Legrand, Nicolas, Lim, Annick, Strick-Marchand, Helene, Mention, Jean-Jacques, Plet, Ariane, Weijer, Kees, Jacques, Yannick, Becker, Pablo D., Guzman, Carlos, Soussan, Patrick, Kremsdorf, Dina, Spits, Hergen, Di Santo, James P., Ma, Averil

“…Cytokine immunothérapies targeting T lymphocytes are attractive clinical interventions against viruses and tumors. In the mouse, the homeostasis of memory α/β…”
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A novel mouse model for stable engraftment of a human immune system and human hepatocytes by Strick-Marchand, Helene, Dusséaux, Mathilde, Darche, Sylvie, Huntington, Nicholas D, Legrand, Nicolas, Masse-Ranson, Guillemette, Corcuff, Erwan, Ahodantin, James, Weijer, Kees, Spits, Hergen, Kremsdorf, Dina, Di Santo, James P

“…Hepatic infections by hepatitis B virus (HBV), hepatitis C virus (HCV) and Plasmodium parasites leading to acute or chronic diseases constitute a global health…”
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Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx by SIRMA, H, GIANNINI, C, POUSSIN, K, PATERLINI, P, KREMSDORF, D, BRECHOT, C

“…Chronic infection by HBV is the leading cause of hepatocellular carcinoma in man. Several lines of evidence suggest that the viral transactivator HBx plays a…”
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Expression of Defective Hepatitis B Virus Particles Derived from Singly Spliced RNA Is Related to Liver Disease by Soussan, Patrick, Pol, Jonathan, Garreau, Florianne, Schneider, Veronique, Le Pendeven, Catherine, Nalpas, Bertrand, Lacombe, Karine, Bonnard, Philippe, Pol, Stanislas, Kremsdorf, Dina

“…Background. Defective hepatitis B virus (HBV) particles, generated from singly spliced HBV RNA, have been detected in chronic carriers of HBV. The present…”
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Bipotential Mouse Embryonic Liver Stem Cell Lines Contribute to Liver Regeneration and Differentiate as Bile Ducts and Hepatocytes by Strick-Marchand, Hélène, Morosan, Serban, Charneau, Pierre, Kremsdorf, Dina, Weiss, Mary C., Darnell, James E.

“…Cell lines have many advantages: they can be manipulated genetically, expanded, and stockpiled for organ transplantation. Freshly isolated hepatocytes, oval…”
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Production of hepatitis B defective particles is dependent on liver status by Redelsperger, Francois, Lekbaby, Bouchra, Mandouri, Yassmina, Giang, Eric, Duriez, Marion, Desire, Nathalie, Roque Afonso, Anne-marie, Brichler, Segolene, Dubreuil, Pascal, Dobrin, Anca, Perlemuter, Gabriel, Prevot, Sophie, Bacon, Nathalie, Grange, Jean Didier, Zatla, Fadila, Le Pendeven, Catherine, Pol, Stanislas, Strick-Marchand, Helene, Di Santo, James, Kremsdorf, Dina, Soussan, Patrick

“…Abstract Defective hepatitis B virus (dHBV) generated from spliced RNA is detected in the sera of HBV-chronic carriers. Our study was designed to determine…”
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Plasticity of Hepatic Cell Differentiation: Bipotential Adult Mouse Liver Clonal Cell Lines Competent to Differentiate In Vitro and In Vivo by Fougère‐Deschatrette, Catherine, Imaizumi‐Scherrer, Tereza, Strick‐Marchand, Hélène, Morosan, Serban, Charneau, Pierre, Kremsdorf, Dina, Faust, Daniela M., Weiss, Mary C.

“…In fetal liver, bipotential hepatoblasts differentiate into hepatocytes and bile duct cells (cholangiocytes). The persistence of such progenitor cells in adult…”
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Inhibition of Hepatitis B Virus Replication by the Interferon-Inducible MxA Protein by Gordien, E, Rosmorduc, O, Peltekian, C, Garreau, F, Bréchot, C, Kremsdorf, D

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In vivo expression of a new hepatitis B virus protein encoded by a spliced RNA by Soussan, P, Garreau, F, Zylberberg, H, Ferray, C, Brechot, C, Kremsdorf, D

“…Hepatitis B virus (HBV) is a small DNA virus with a compact genomic organization. All HBV proteins identified to date have been encoded by unspliced HBV RNAs…”
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Identification, using cDNA macroarray analysis, of distinct gene expression profiles associated with pathological and virological features of hepatocellular carcinoma by DELPUECH, Oona, TRABUT, Jean-Baptiste, CARNOT, Francoise, FEUILLARD, Jean, BRECHOT, Christian, KREMSDORF, Dina

“…It is still unclear as to whether the gene expression profile in HCV- or HBV-related HCC exhibits a degree of specificity and whether the development of HCC in…”
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Hepatitis B Virus Splice-Generated Protein Induces T-Cell Responses in HLA-Transgenic Mice and Hepatitis B Virus-Infected Patients by MANCINI -BOURGINE, Maryline, BAYARD, Florence, SOUSSAN, Patrick, QIANG DENG, LONE, Yu-Chun, KREMSDORF, Dina, MICHEL, Marie-Louise

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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