Search Results - "Krempler, F"
-
1
PGC-1α : a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes
Published in Diabetologia (01-07-2006)Get full text
Journal Article -
2
Aberrant hepatic TRIB3 gene expression in insulin-resistant obese humans
Published in Diabetologia (01-09-2010)“…Aims/hypothesis The pseudokinase tribbles homologue 3 (Drosophila) (TRIB3) negatively interferes with insulin-mediated phosphorylation and activation of v-akt…”
Get full text
Journal Article -
3
Role of genetic polymorphisms at the adiponectin gene in regulation of adiponectin gene expression and circulating adiponectin levels
Published in Atherosclerosis (01-09-2016)Get full text
Journal Article -
4
Hepatic adiponectin receptors (ADIPOR) 1 and 2 mRNA and their relation to insulin resistance in obese humans
Published in International Journal of Obesity (01-05-2010)“…Objective: Adiponectin signalling attenuates insulin resistance (IR) and steatosis hepatis in animal models. As adiponectin receptor (ADIPOR)1 and ADIPOR2 are…”
Get full text
Journal Article -
5
SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population
Published in International Journal of Obesity (01-07-2007)“…Context: The sterol regulatory element-binding protein-1c (SREBP-1c) is a transcription factor involved in the regulation of lipid and glucose metabolism and…”
Get full text
Journal Article -
6
Associations of the UCP2 Gene Locus With Asymptomatic Carotid Atherosclerosis in Middle-Aged Women
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2005)“…OBJECTIVE—Reactive oxygen species (ROS) contribute to atherogenesis. Uncoupling protein 2 (UCP2) reduces mitochondrial ROS generation and protects against the…”
Get full text
Journal Article -
7
Determinants of plasma apolipoprotein A‐V and APOA5 gene transcripts in humans
Published in Journal of internal medicine (01-11-2008)“… Objective. Apolipoprotein A‐V (apoAV) contributes to the regulation of triglyceride metabolism, which plays a role in the pathogenesis of atherosclerotic…”
Get full text
Journal Article -
8
Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans
Published in Journal of lipid research (01-10-1997)“…The mitochondrial uncoupling protein (UCP), which is exclusively expressed in brown adipose tissue, regulates energy expenditure in rodents but its importance…”
Get full text
Journal Article -
9
Uncoupling protein-2 gene : reduced mRNA expression in intraperitoneal adipose tissue of obese humans
Published in Diabetologia (01-08-1998)“…The mitochondrial uncoupling protein-2 (UCP-2) is a recently discovered homologue of the brown adipose tissue-specific uncoupling protein and could be involved…”
Get full text
Journal Article -
10
The Gln27Glu polymorphism in the β2-adrenergic receptor gene is not associated with morbid obesity in Austrian women
Published in International Journal of Obesity (13-04-2000)Get full text
Journal Article -
11
The complement system: a pathway linking host defence and adipocyte biology
Published in European journal of clinical investigation (01-08-1999)Get full text
Journal Article -
12
Uncoupling protein-3 gene expression : reduced skeletal muscle mRNA in obese humans during pronounced weight loss
Published in Diabetologia (01-03-1999)“…Uncoupling protein-3 is a member of a protein family that serves to dissipate energy in the form of heat thereby modulating energy expenditure. Alternative…”
Get full text
Journal Article -
13
The Uncoupling Protein-3 Gene Is Transcribed from Tissue-specific Promoters in Humans but Not in Rodents
Published in The Journal of biological chemistry (17-11-2000)“…Uncoupling protein-3 (UCP3), a mitochondrial membrane transporter, is a candidate effector of thermogenesis. Even though mice with targeted disruption of the…”
Get full text
Journal Article -
14
Studies on the role of specific cell surface receptors in the removal of lipoprotein (a) in man
Published in The Journal of clinical investigation (01-05-1983)“…The binding of 125I-lipoprotein (a) [Lp(a)] to cell surface receptors was studied on cultured human fibroblasts. The results were compared with corresponding…”
Get full text
Journal Article -
15
A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
Published in Nature genetics (01-06-2001)“…Obesity is the most common nutritional disorder in Western society. Uncoupling protein-2 (UCP2) is a recently identified member of the mitochondrial…”
Get full text
Journal Article -
16
Potentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor gamma co-activator 1 alpha
Published in Biochemical journal (01-04-2003)“…Peroxisome-proliferator-activated receptor (PPAR) gamma co-activator 1 alpha (PGC-1 alpha/PPARGC1) plays an important role in energy metabolism by…”
Get full text
Journal Article -
17
Turnover of lipoprotein (a) in man
Published in The Journal of clinical investigation (01-06-1980)“…An elevated concentration of lipoprotein (a) [Lp(a)] in the serum has been considered a risk factor for coronary heart disease by various investigators. In the…”
Get full text
Journal Article -
18
Role of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α in the Transcriptional Regulation of the Human Uncoupling Protein 2 Gene in INS-1E Cells
Published in Endocrinology (Philadelphia) (01-02-2006)“…A role of uncoupling protein 2 (UCP2) as negative modulator of insulin secretion has been suggested, but the transcriptional pathways regulating β-cell UCP2…”
Get full text
Journal Article -
19
Human Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 (PPARGC1) Gene: cDNA Sequence, Genomic Organization, Chromosomal Localization, and Tissue Expression
Published in Genomics (San Diego, Calif.) (15-11-1999)“…Brown adipose and muscle tissues can increase energy expenditure via adaptive thermogenesis, thereby protecting against obesity. Mouse peroxisome proliferator…”
Get full text
Journal Article -
20