Search Results - "Kremer, Philip H C"

Therapeutic Hypothermia and the Risk of Infection: A Systematic Review and Meta-Analysis by Geurts, Marjolein, Macleod, Malcolm R, Kollmar, Rainer, Kremer, Philip H C, van der Worp, H Bart

“…OBJECTIVE:Observational studies suggest that infections are a common complication of therapeutic hypothermia. We performed a systematic review and…”
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Pneumococcal genetic variability in age-dependent bacterial carriage by Kremer, Philip H C, Ferwerda, Bart, Bootsma, Hester J, Rots, Nienke Y, Wijmenga-Monsuur, Alienke J, Sanders, Elisabeth A M, Trzciński, Krzysztof, Wyllie, Anne L, Turner, Paul, van der Ende, Arie, Brouwer, Matthijs C, Bentley, Stephen D, van de Beek, Diederik, Lees, John A

“…The characteristics of pneumococcal carriage vary between infants and adults. Host immune factors have been shown to contribute to these age-specific…”
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Risk Factors for Lobar and Non-Lobar Intracerebral Hemorrhage in Patients with Vascular Disease by Kremer, Philip H C, Jolink, Wilmar M T, Kappelle, L Jaap, Algra, Ale, Klijn, Catharina J M

“…Lobar and non-lobar non-traumatic intracerebral hemorrhage (ICH) are presumably caused by different types of small vessel diseases. The aim of this study was…”
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Large scale genomic analysis shows no evidence for pathogen adaptation between the blood and cerebrospinal fluid niches during bacterial meningitis by Lees, John A, Kremer, Philip H C, Manso, Ana S, Croucher, Nicholas J, Ferwerda, Bart, Serón, Mercedes Valls, Oggioni, Marco R, Parkhill, Julian, Brouwer, Matthijs C, van der Ende, Arie, van de Beek, Diederik, Bentley, Stephen D

“…Recent studies have provided evidence for rapid pathogen genome diversification, some of which could potentially affect the course of disease. We have…”
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Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis by Kremer, Philip H C, Lees, John A, Ferwerda, Bart, van de Ende, Arie, Brouwer, Matthijs C, Bentley, Stephen D, van de Beek, Diederik

“…causes sepsis and meningitis in humans. It has been suggested that pathogen genetic variation determines variance in disease severity. Here we report results…”
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Cognitive Effects of Three β-Adrenoceptor Acting Drugs in Healthy Volunteers and Patients with Parkinson’s Disease by Eijsvogel, Pepijn P.N.M., Borghans, Laura G.J.M., Prins, Samantha, Moss, Laurence, van Kraaij, Sebastiaan J.W., van Brummelen, Emilie, Klaassen, Erica, Martin, Renee S., Bautista, Edgar, Ford, Anthony P., Kremer, Philip H.C., Groeneveld, Geert Jan, Vargas, Gabriel A.

“…Background: Noradrenergic signaling declines in Parkinson’s disease (PD) following locus coeruleus neurodegeneration. Epidemiologic studies demonstrate that…”
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Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis by Lees, John A., Ferwerda, Bart, Kremer, Philip H. C., Wheeler, Nicole E., Serón, Mercedes Valls, Croucher, Nicholas J., Gladstone, Rebecca A., Bootsma, Hester J., Rots, Nynke Y., Wijmega-Monsuur, Alienke J., Sanders, Elisabeth A. M., Trzciński, Krzysztof, Wyllie, Anne L., Zwinderman, Aeilko H., van den Berg, Leonard H., van Rheenen, Wouter, Veldink, Jan H., Harboe, Zitta B., Lundbo, Lene F., de Groot, Lisette C. P. G. M., van Schoor, Natasja M., van der Velde, Nathalie, Ängquist, Lars H., Sørensen, Thorkild I. A., Nohr, Ellen A., Mentzer, Alexander J., Mills, Tara C., Knight, Julian C., du Plessis, Mignon, Nzenze, Susan, Weiser, Jeffrey N., Parkhill, Julian, Madhi, Shabir, Benfield, Thomas, von Gottberg, Anne, van der Ende, Arie, Brouwer, Matthijs C., Barrett, Jeffrey C., Bentley, Stephen D., van de Beek, Diederik

“…Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and…”
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Diversification in immunogenicity genes caused by selective pressures in invasive meningococci by Kremer, Philip H C, Lees, John A, Ferwerda, Bart, Bijlsma, Merijn W, MacAlasdair, Neil, van der Ende, Arie, Brouwer, Matthijs C, Bentley, Stephen D, van de Beek, Diederik

“…We studied population genomics of 486 isolates causing meningitis in the Netherlands during the period 1979-2003 and 2006-2013 using whole-genome sequencing to…”
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Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain by Kremer, P H C, Koeleman, B P C, Pawlikowska, L, Weinsheimer, S, Bendjilali, N, Sidney, S, Zaroff, J G, Rinkel, G J E, van den Berg, L H, Ruigrok, Y M, de Kort, G A P, Veldink, J H, Kim, H, Klijn, C J M

“…Background In genome-wide association studies (GWAS) five putative risk loci are associated with intracranial aneurysm. As brain arteriovenous malformations…”
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Risk Factors for Lobar and Non-Lobar Intracerebral Hemorrhage in Patients with Vascular Disease: e0142338 by Kremer, Philip HC, Jolink, Wilmar MT, Kappelle, L Jaap, Algra, Ale, Klijn, Catharina JM

“…Introduction Lobar and non-lobar non-traumatic intracerebral hemorrhage (ICH) are presumably caused by different types of small vessel diseases. The aim of…”
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