Search Results - "Kremer, H. P."

Effects of a population-based, person-centred and integrated care service on health, wellbeing and self-management of community-living older adults: A randomised controlled trial on Embrace by Spoorenberg, Sophie L W, Wynia, Klaske, Uittenbroek, Ronald J, Kremer, Hubertus P H, Reijneveld, Sijmen A

“…To evaluate the effects of the population-based, person-centred and integrated care service 'Embrace' at twelve months on three domains comprising health,…”
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Genotype―phenotype correlations in spastic paraplegia type 7: a study in a large Dutch cohort by VAN GASSEN, Koen L. I, VAN DER HEIJDEN, Charlotte D. C. C, VAN DE WARRENBURG, Bart P, DE BOT, Susanne T, DEN DUNNEN, Wilfred F. A, VAN DEN BERG, Leonard H, VERSCHUUREN-BEMELMANS, Corien C, KREMER, H. P. H, VELDINK, Jan H, KAMSTEEG, Erik-Jan, SCHEFFER, Hans

“…Spastic paraplegia type 7 is an autosomal recessive neurodegenerative disorder mainly characterized by progressive bilateral lower limb spasticity and referred…”
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Experiences of Community-Living Older Adults Receiving Integrated Care Based on the Chronic Care Model: A Qualitative Study by Spoorenberg, Sophie L W, Wynia, Klaske, Fokkens, Andrea S, Slotman, Karin, Kremer, Hubertus P H, Reijneveld, Sijmen A

“…Integrated care models aim to solve the problem of fragmented and poorly coordinated care in current healthcare systems. These models aim to be…”
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Cerebral Autoregulation in Stroke A Review of Transcranial Doppler Studies by ARIES, Marcel J. H, ELTING, Jan W, DE KEYSER, Jacques, KREMER, Berry P. H, VROOMEN, Patrick C. A. J

“…Cerebral autoregulation may become impaired after stroke. To provide a review of the nature and extent of any autoregulation impairment after stroke and its…”
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Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice by Kruit, J. K, Kremer, P. H. C, Dai, L, Tang, R, Ruddle, P, de Haan, W, Brunham, L. R, Verchere, C. B, Hayden, M. R

“…Aims/hypothesis Cellular cholesterol accumulation is an emerging mechanism for beta cell dysfunction in type 2 diabetes. Absence of the cholesterol transporter…”
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Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain by Kremer, P H C, Koeleman, B P C, Pawlikowska, L, Weinsheimer, S, Bendjilali, N, Sidney, S, Zaroff, J G, Rinkel, G J E, van den Berg, L H, Ruigrok, Y M, de Kort, G A P, Veldink, J H, Kim, H, Klijn, C J M

“…Background In genome-wide association studies (GWAS) five putative risk loci are associated with intracranial aneurysm. As brain arteriovenous malformations…”
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Functional analysis helps to define KCNC3 mutational spectrum in Dutch ataxia cases by Duarri, Anna, Nibbeling, Esther A R, Fokkens, Michiel R, Meijer, Michel, Boerrigter, Melissa, Verschuuren-Bemelmans, Corien C, Kremer, Berry P H, van de Warrenburg, Bart P, Dooijes, Dennis, Boddeke, Erik, Sinke, Richard J, Verbeek, Dineke S

“…Spinocerebellar ataxia type 13 (SCA13) is an autosomal dominantly inherited neurodegenerative disorder of the cerebellum caused by mutations in the voltage…”
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CSF neurofilament proteins in the differential diagnosis of dementia by de Jong, D, Jansen, R W M M, Pijnenburg, Y A L, van Geel, W J A, Borm, G F, Kremer, H P H, Verbeek, M M

“…Background: Neurofilament (NF) proteins are major cytoskeletal constituents of neurons. Increased CSF NF levels may reflect neuronal degeneration. Objective:…”
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Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population‐based study by Rosso, Sonia M., Kaat, Laura Donker, Baks, Timo, Joosse, Marijke, de Koning, Inge, Pijnenburg, Yolande, de Jong, Daniëlle, Dooijes, Dennis, Kamphorst, Wouter, Ravid, Rivka, Niermeijer, Martinus F., Verheij, Frans, Kremer, H. P., Scheltens, Philip, van Duijn, Cornelia M., Heutink, Peter, van Swieten, John C.

“…Since 1994, a population‐based study of frontotemporal dementia (FTD) in The Netherlands has aimed to ascertain all patients with FTD, and first prevalence…”
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Cerebrospinal fluid amyloid β40 is decreased in cerebral amyloid angiopathy by Verbeek, Marcel M., Kremer, Berry P. H., Rikkert, Marcel Olde, Van Domburg, Peter H. M. F., Skehan, Maureen E., Greenberg, Steven M.

“…Cerebral amyloid angiopathy is caused by deposition of the amyloid β protein in the cerebral vasculature. In analogy to previous observations in Alzheimer…”
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Childhood white matter disorders: quantitative MR imaging and spectroscopy by van der Voorn, J Patrick, Pouwels, Petra J W, Hart, Augustinus A M, Serrarens, Judith, Willemsen, Michèl A A P, Kremer, Hubertus P H, Barkhof, Frederik, van der Knaap, Marjo S

“…To prospectively investigate whether quantitative magnetic resonance (MR) parameters, including magnetization transfer ratio (MTR), apparent diffusion…”
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Pure adult-onset Spastic Paraplegia caused by a novel mutation in the KIAA0196 (SPG8) gene by de Bot, Susanne T., Vermeer, Sascha, Buijsman, Wendy, Heister, Angelien, Voorendt, Marsha, Verrips, Aad, Scheffer, Hans, Kremer, Hubertus P. H., van de Warrenburg, Bart P. C., Kamsteeg, Erik-Jan

“…SPG8 is a rare autosomal dominant hereditary spastic paraplegia (AD-HSP), with only six SPG8 families described so far. Our purpose was to screen for KIAA0196…”
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Striatal metabolism and psychomotor speed as predictors of motor onset in Huntington’s disease by Herben-Dekker, Meike, van Oostrom, Joost C. H., Roos, Raymund A. C., Jurgens, Caroline K., Witjes-Ané, Marie-Noëlle W., Kremer, Hubertus P. H., Leenders, Klaus L., Spikman, Jacoba M.

“…The clinical diagnosis of Huntington’s disease (HD) is based on the motor symptoms, although these can be preceded by cognitive and behavioral changes…”
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Adult metachromatic leukodystrophy treated by allo-SCT and a review of the literature by de Hosson, L D, van de Warrenburg, B P C, Preijers, F W M B, Blijlevens, N M A, van der Reijden, B A, Kremer, H P H, Lefeber, D J, Allebes, W A, Al-Ali, H, Niederwieser, D W, Schaap, N P M, Schattenberg, A V M B

“…Five patients with adult-onset metachromatic leukodystrophy (MLD) underwent allo-SCT. Conditioning was reduced in intensity and grafts were obtained from…”
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Hereditary spastic paraplegia due to SPAST mutations in 151 Dutch patients: new clinical aspects and 27 novel mutations by de Bot, S T, van den Elzen, R T M, Mensenkamp, A R, Schelhaas, H J, Willemsen, M A A P, Knoers, N V A M, Kremer, H P H, van de Warrenburg, B P C, Scheffer, H

“…BackgroundIn the clinically and genetically heterogeneous group of the hereditary spastic paraplegias (HSPs), mutations in the SPAST gene are most frequently…”
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Falls in Spinocerebellar Ataxias: Results of the EuroSCA Fall Study by Fonteyn, Ella M. R., Schmitz-Hübsch, Tanja, Verstappen, Carla C., Baliko, Laslo, Bloem, Bastiaan R., Boesch, Silvia, Bunn, Lisa, Charles, Perrine, Dürr, Alexandra, Filla, Allesandro, Giunti, Paola, Globas, Christoph, Klockgether, Thomas, Melegh, Bela, Pandolfo, Massimo, De Rosa, Anna, Schöls, Ludger, Timmann, Dagmar, Munneke, Marten, Kremer, Berry P. H., van de Warrenburg, Bart P. C.

“…To investigate the frequency, details, and consequences of falls in patients with autosomal dominant spinocerebellar ataxias (SCAs) and to derive specific…”
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Mapping of the SCA23 locus involved in autosomal dominant cerebellar ataxia to chromosome region 20p13-12.3 by Verbeek, D. S., van de Warrenburg, B. P., Wesseling, P., Pearson, P. L., Kremer, H. P., Sinke, R. J.

“…We report upon a Dutch autosomal dominant cerebellar ataxia (ADCA) family, clinically characterized by a late-onset (>40 years), slowly progressive, isolated…”
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ATL1 and REEP1 mutations in hereditary and sporadic upper motor neuron syndromes by de Bot, S. T., Veldink, J. H., Vermeer, S., Mensenkamp, A. R., Brugman, F., Scheffer, H., van den Berg, L. H., Kremer, H. P. H., Kamsteeg, E. J., van de Warrenburg, B. P.

“…SPAST mutations are the most common cause of autosomal dominant hereditary spastic paraplegias (AD-HSPs), but many spastic paraplegia patients are found to…”
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Integrated and Person‐Centered Care for Community‐Living Older Adults: A Cost‐Effectiveness Study by Uittenbroek, Ronald J., Asselt, Antoinette D. I., Spoorenberg, Sophie L. W., Kremer, Hubertus P. H., Wynia, Klaske, Reijneveld, Sijmen A.

“…Objectives To assess the cost‐effectiveness of Embrace, an integrated primary care service for older adults. Data Sources Care and support claims from health…”
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Cerebellar ataxia and congenital disorder of glycosylation Ia (CDG-Ia) with normal routine CDG screening by Vermeer, S, Kremer, H P H, Leijten, Q H, Scheffer, H, Matthijs, G, Wevers, R A, Knoers, N A V M, Morava, E, Lefeber, D J

“…Cerebellar ataxia can have many genetic causes among which are the congenital disorders of glycosylation type I (CDG-I). In this group of disorders, a…”
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