Search Results - "Krementsov, D N"

Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity by Bearoff, F, del Rio, R, Case, L K, Dragon, J A, Nguyen-Vu, T, Lin, C-Y, Blankenhorn, E P, Teuscher, C, Krementsov, D N

“…Regulation of gene expression in immune cells is known to be under genetic control, and likely contributes to susceptibility to autoimmune diseases such as…”
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Myosin V: Regulation by Calcium, Calmodulin, and the Tail Domain by Krementsov, Dimitry N., Krementsova, Elena B., Trybus, Kathleen M.

“…Calcium activates the ATPase activity of tissue-purified myosin V, but not that of shorter expressed constructs. Here, we resolve this discrepancy by comparing…”
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The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease by Case, Laure K, Wall, Emma H, Dragon, Julie A, Saligrama, Naresha, Krementsov, Dimitry N, Moussawi, Mohamad, Zachary, James F, Huber, Sally A, Blankenhorn, Elizabeth P, Teuscher, Cory

“…Understanding the DNA elements that constitute and control the regulatory genome is critical for the appropriate therapeutic management of complex diseases…”
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Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant by Boisson-Dupuis, Stéphanie, Ramirez-Alejo, Noe, Li, Zhi, Patin, Etienne, Rao, Geetha, Kerner, Gaspard, Lim, Che Kang, Krementsov, Dimitry N, Hernandez, Nicholas, Ma, Cindy S, Zhang, Qian, Markle, Janet, Martinez-Barricarte, Ruben, Payne, Kathryn, Fisch, Robert, Deswarte, Caroline, Halpern, Joshua, Bouaziz, Matthieu, Mulwa, Jeanette, Sivanesan, Durga, Lazarov, Tomi, Naves, Rodrigo, Garcia, Patricia, Itan, Yuval, Boisson, Bertrand, Checchi, Alix, Jabot-Hanin, Fabienne, Cobat, Aurélie, Guennoun, Andrea, Jackson, Carolyn C, Pekcan, Sevgi, Caliskaner, Zafer, Inostroza, Jaime, Costa-Carvalho, Beatriz Tavares, de Albuquerque, Jose Antonio Tavares, Garcia-Ortiz, Humberto, Orozco, Lorena, Ozcelik, Tayfun, Abid, Ahmed, Rhorfi, Ismail Abderahmani, Souhi, Hicham, Amrani, Hicham Naji, Zegmout, Adil, Geissmann, Frédéric, Michnick, Stephen W, Muller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Puel, Anne, Ciancanelli, Michael J, Marr, Nico, Abolhassani, Hassan, Balcells, María Elvira, Condino-Neto, Antonio, Strickler, Alexis, Abarca, Katia, Teuscher, Cory, Ochs, Hans D, Reisli, Ismail, Sayar, Esra H, El-Baghdadi, Jamila, Bustamante, Jacinta, Hammarström, Lennart, Tangye, Stuart G, Pellegrini, Sandra, Quintana-Murci, Lluis, Abel, Laurent, Casanova, Jean-Laurent

“…Inherited IL-12Rβ1 and TYK2 deficiencies impair both IL-12- and IL-23-dependent IFN-γ immunity and are rare monogenic causes of tuberculosis, each found in…”
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