Search Results - "Krejčová, Gabriela"

On the origin of the functional versatility of macrophages by Bajgar, Adam, Krejčová, Gabriela

“…Macrophages represent the most functionally versatile cells in the animal body. In addition to recognizing and destroying pathogens, macrophages remove…”
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Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense by Krejčová, Gabriela, Danielová, Adéla, Nedbalová, Pavla, Kazek, Michalina, Strych, Lukáš, Chawla, Geetanjali, Tennessen, Jason M, Lieskovská, Jaroslava, Jindra, Marek, Doležal, Tomáš, Bajgar, Adam

“…Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory…”
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Polarization of Macrophages in Insects: Opening Gates for Immuno-Metabolic Research by Bajgar, Adam, Krejčová, Gabriela, Doležal, Tomáš

“…Insulin resistance and cachexia represent severe metabolic syndromes accompanying a variety of human pathological states, from life-threatening cancer and…”
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Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster by Krejčová, Gabriela, Saloň, Ivan, Klimša, Vojtěch, Ulbrich, Pavel, Aysan, Ayse Beyza, Bajgar, Adam, Štěpánek, František

“…Currently available methods for cell separation are generally based on fluorescent labeling using either endogenously expressed fluorescent markers or the…”
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Yeast glucan particles enable intracellular protein delivery in Drosophila without compromising the immune system by Bajgar, Adam, Saloň, Ivan, Krejčová, Gabriela, DoleŽal, Tomáš, Jindra, Marek, Štěpánek, František

“…Glucan particles derived from yeast have been recently proposed as potential drug delivery carriers. Here, we demonstrate the potential of glucan particles for…”
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Liver macrophages regulate systemic metabolism through non-inflammatory factors by Morgantini, Cecilia, Jager, Jennifer, Li, Xidan, Levi, Laura, Azzimato, Valerio, Sulen, André, Barreby, Emelie, Xu, Connie, Tencerova, Michaela, Näslund, Erik, Kumar, Chanchal, Verdeguer, Francisco, Straniero, Sara, Hultenby, Kjell, Björkström, Niklas K., Ellis, Ewa, Rydén, Mikael, Kutter, Claudia, Hurrell, Tracey, Lauschke, Volker M., Boucher, Jeremie, Tomčala, Aleš, Krejčová, Gabriela, Bajgar, Adam, Aouadi, Myriam

“…Liver macrophages (LMs) have been proposed to contribute to metabolic disease through secretion of inflammatory cytokines. However, anti-inflammatory drugs…”
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The people behind the papers - Gabriela Krejčová and Adam Bajgar

“…Macrophages maintain tissue homeostasis by removing old, damaged and apoptotic cells. During metamorphosis, the fruit fly larval fat body undergoes cell death…”
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Macrophages play a nutritive role in post-metamorphic maturation in Drosophila by Krejčová, Gabriela, Danielová, Adéla, Sehadová, Hana, Dyčka, Filip, Kubásek, Jiří, Moos, Martin, Bajgar, Adam

“…In the body of multicellular organisms, macrophages play an indispensable role in maintaining tissue homeostasis by removing old, apoptotic and damaged cells…”
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Effective cancer immunotherapy based on combination of TLR agonists with stimulation of phagocytosis by Caisová, Veronika, Uher, Ondřej, Nedbalová, Pavla, Jochmanová, Ivana, Kvardová, Karolína, Masáková, Kamila, Krejčová, Gabriela, Paďouková, Lucie, Chmelař, Jindřich, Kopecký, Jan, Ženka, Jan

“…Immunotherapy emerges as a fundamental approach in cancer treatment. Up to date, the efficacy of numerous different immunotherapies has been evaluated. The use…”
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Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection by Krejčová, Gabriela, Morgantini, Cecilia, Zemanová, Helena, Lauschke, Volker M, Kovářová, Julie, Kubásek, Jiří, Nedbalová, Pavla, Kamps‐Hughes, Nick, Moos, Martin, Aouadi, Myriam, Doležal, Tomáš, Bajgar, Adam

“…The immune response is an energy‐demanding process that must be coordinated with systemic metabolic changes redirecting nutrients from stores to the immune…”
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Innate immunity based cancer immunotherapy: B16-F10 murine melanoma model by Caisová, Veronika, Vieru, Andra, Kumžáková, Zuzana, Glaserová, Simona, Husníková, Hana, Vácová, Nikol, Krejčová, Gabriela, Paďouková, Lucie, Jochmanová, Ivana, Wolf, Katherine I, Chmelař, Jindřich, Kopecký, Jan, Ženka, Jan

“…Using killed microorganisms or their parts to stimulate immunity for cancer treatment dates back to the end of 19 century. Since then, it undergone…”
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Inhibition of mevalonate pathway by macrophage‐specific delivery of atorvastatin prevents their pro‐inflammatory polarisation by Krejčová, Gabriela, Ruphuy, Gabriela, Šalamúnová, Petra, Sonntag, Erik, Štěpánek, František, Bajgar, Adam

“…Adjustment of the cellular metabolism of pro‐inflammatory macrophages is essential for their bactericidal function; however, it underlies the development of…”
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Anticholinergic drugs--functional antidotes for the treatment of tabun intoxication by Krejcová, Gabriela, Kassa, Jirí

“…1. To study the influence of antidotes on tabun-induced neurotoxicity, the rats were injected intramuscularly with organophosphate tabun (LD50). The efficacy…”
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The impairment of spatial memory following low-level sarin inhalation exposure and antidotal treatment in rats by Kassa, Jirí, Krejcová, Gabriela, Vachek, Josef

“…1. To study the influence of antidotes on low-level sarin-induced impairment of cognitive functions, the rats were exposed to three various low concentrations…”
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Effect of atropine and the oxime HI-6 on low-level sarin-induced alteration of performance of rats in a T-maze by Krejcová, Gabriela, Kassa, Jirí, Vachek, Josef

“…1. To study the influence of antidotes on low-level sarin-induced alteration of cognitive functions, male albino Wistar rats were exposed to three various low…”
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A comparison of the neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in soman-poisoned rats by Kassa, Jirí, Krejcová, Gabriela, Samnaliev, Ivan

“…1. To study the influence of pharmacological pretreatment (PANPAL or pyridostigmine combined with biperiden) and antidotal treatment (the oxime HI-6 plus…”
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Antiacetylcholinesterase activity of cyclosporine--a comparison of single and repeated administration and effect of 7-methoxytacrine by Herink, Josef, Krejcová, Gabriela, Bajgar, Jirí

“…The aim of this work is a comparison of single and repeated peroral administration of cyclosporine (CsA) and the interaction of repeated administration of CsA…”
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In vitro reactivation of acetylcholinesterase inhibited by cyclosarin using bisquaternary pyridinium aldoximes K005, K033, K027 AND K048 by Kuca, Kamil, Sevelová-Bartosová, Lucie, Krejcová-Kunesová, Gabriela

“…We have tested four new bisquaternary pyridinium acetylcholinesterase (AChE; EC 3.1.1.7) reactivators - K005 (1,3-bis(2-hydroxyiminomethylpyridinium) propane…”
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Antidotal treatment of GF-agent intoxication in mice with bispyridinium oximes by Sevelova, L, Kuca, K, Krejcova-Kunesova, G

“…It was shown that intoxications with GF-agent are rather resistant to convential oxime therapy; therefore, the development of new oximes in an effort to…”
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Biochemical and Behavioral Effects of Soman Vapors in Low Concentrations by Bajgar, Jiri, Ševelová, Lucie, Krej ová, Gabriela, Fusek, Josef, Vachek, Josef, Kassa, Jiri, Herink, Josef, Jong, Leo P. A., Benschop, Hendrik P.

“…Soman belongs to the most dangerous nerve agents because of the low effectiveness of the presently available antidotes. Soman acts by inhibiting…”
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