Note: multiplexed multiple-tau auto- and cross-correlators on a single field programmable gate array

We introduce a new multiple-tau hardware correlator design for computing fluorescence correlation functions (CFs) in real time. Use of hardware resources is minimized by scheduling the computation of different segments of the CFs on a single correlator block. Simultaneous calculation of two multiple...

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Bibliographic Details
Published in:Review of scientific instruments Vol. 83; no. 4; p. 046101
Main Authors: Mocsár, G, Kreith, B, Buchholz, J, Krieger, J W, Langowski, J, Vámosi, G
Format: Journal Article
Language:English
Published: United States 01-04-2012
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Summary:We introduce a new multiple-tau hardware correlator design for computing fluorescence correlation functions (CFs) in real time. Use of hardware resources is minimized by scheduling the computation of different segments of the CFs on a single correlator block. Simultaneous calculation of two multiple-tau autocorrelation (ACFs) and two cross-correlation functions (CCFs) is implemented in LabVIEW on a National Instruments field programmable gate array (FPGA) card with a minimal sampling time of 400 ns. Raw data are stored with a time resolution of 50 ns. The design can be easily adapted to other FPGA cards and extended to more inputs.
ISSN:1089-7623
DOI:10.1063/1.3700810