Search Results - "Kreilaus, Fabian"

Medium-Dose Chronic Cannabidiol Treatment Reverses Object Recognition Memory Deficits of APPSwe/PS1ΔE9 Transgenic Female Mice by Coles, Madilyn, Watt, Georgia, Kreilaus, Fabian, Karl, Tim

“…Alzheimer’s disease (AD) is a neurodegenerative disease that causes behavioral and cognitive impairments. The phytocannabinoid cannabidiol (CBD) has…”
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Cholesteryl ester levels are elevated in the caudate and putamen of Huntington’s disease patients by Phillips, Gabrielle R., Hancock, Sarah E., Brown, Simon H. J., Jenner, Andrew M., Kreilaus, Fabian, Newell, Kelly A., Mitchell, Todd W.

“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative illness caused by a mutation in the huntingtin gene (HTT) and subsequent protein (mhtt),…”
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Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue by Kreilaus, Fabian, Spiro, Adena S., McLean, Catriona A., Garner, Brett, Jenner, Andrew M.

“…Aims Cholesterol plays an essential role in membrane structure and function, being especially important in the brain. Alteration of brain cholesterol synthesis…”
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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background by Lum, Jeremy S., Brown, Mikayla L., Farrawell, Natalie E., McAlary, Luke, Ly, Diane, Chisholm, Christen G., Snow, Josh, Vine, Kara L., Karl, Tim, Kreilaus, Fabian, McInnes, Lachlan E., Nikseresht, Sara, Donnelly, Paul S., Crouch, Peter J., Yerbury, Justin J.

“…The synthetic copper-containing compound, CuATSM, has emerged as one of the most promising drug candidates developed for the treatment of amyotrophic lateral…”
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Detection of retinal and blood Aβ oligomers with nanobodies by Habiba, Umma, Descallar, Joseph, Kreilaus, Fabian, Adhikari, Utpal K., Kumar, Sachin, Morley, John W, Bui, Bang V, Koronyo‐Hamaoui, Maya, Tayebi, Mourad

“…Introduction Abnormal retinal changes are increasingly recognized as an early pathological change in Alzheimer's disease (AD). Although amyloid beta oligomers…”
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Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice by Kreilaus, Fabian, Przybyla, Magdalena, Ittner, Lars, Karl, Tim

“…Frontotemporal dementia (FTD) and Alzheimer’s disease (AD) share the pathological hallmark of intracellular neurofibrillary tangles, which result from the…”
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First behavioural assessment of a novel Immp2l knockdown mouse model with relevance for Gilles de la Tourette syndrome and Autism spectrum disorder by Kreilaus, Fabian, Chesworth, Rose, Eapen, Valsamma, Clarke, Raymond, Karl, Tim

“…Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder, which shares some clinical features with Autism spectrum disorder (ASD). The genetic…”
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Medium-Dose Chronic Cannabidiol Treatment Reverses Object Recognition Memory Deficits of APP Swe /PS1ΔE9 Transgenic Female Mice by Coles, Madilyn, Watt, Georgia, Kreilaus, Fabian, Karl, Tim

“…Alzheimer's disease (AD) is a neurodegenerative disease that causes behavioral and cognitive impairments. The phytocannabinoid cannabidiol (CBD) has…”
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The background and experience of neuroscience teachers in Australian universities: A cross-sectional survey by Todd, Gabrielle, Kreilaus, Fabian, Lonergan, Amy S, Cameron, Melissa S, Double, Kay L

“…Neuroscience is an academic discipline taught within a broad range of university degrees and programs. The expertise and experience of neuroscience teaching…”
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The behavioural phenotype of 14-month-old female TAU58/2 transgenic mice by Kreilaus, Fabian, Masanetz, Rebecca, Watt, Georgia, Przybyla, Magdalena, Ittner, Arne, Ittner, Lars, Karl, Tim

“…Frontotemporal dementia (FTD) and Alzheimer’s disease (AD) exhibit intracellular inclusions [neurofibrillary tangles (NFT’s)] of microtubule-associated protein…”
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Novel behavioural characteristics of the superoxide dismutase 1 G93A (SOD1G93A) mouse model of amyotrophic lateral sclerosis include sex‐dependent phenotypes by Kreilaus, Fabian, Guerra, Stefan, Masanetz, Rebecca, Menne, Victoria, Yerbury, Justin, Karl, Tim

“…Amyotrophic lateral sclerosis (ALS) involves the rapid degeneration of upper and lower motor neurons leading to weakening and paralysis of voluntary movements…”
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Evidence for altered cholesterol metabolism in H untington's disease post mortem brain tissue by Kreilaus, Fabian, Spiro, Adena S., McLean, Catriona A., Garner, Brett, Jenner, Andrew M.

“…Aims Cholesterol plays an essential role in membrane structure and function, being especially important in the brain. Alteration of brain cholesterol synthesis…”
Get full text

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background by Lum, Jeremy S, Brown, Mikayla L, Farrawell, Natalie E, McAlary, Luke, Ly, Diane, Chisholm, Christen G, Snow, Josh, Vine, Kara L, Karl, Tim, Kreilaus, Fabian, McInnes, Lachlan E, Nikseresht, Sara, Donnelly, Paul S, Crouch, Peter J, Yerbury, Justin J

“…The synthetic copper-containing compound, CuATSM, has emerged as one of the most promising drug candidates developed for the treatment of amyotrophic lateral…”
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Therapeutic Effects of Anthocyanins and Environmental Enrichment in R6/1 Huntington's Disease Mice by Kreilaus, Fabian, Spiro, Adena S, Hannan, Anthony J, Garner, Brett, Jenner, Andrew M

“…Huntington's disease (HD) is a progressive neurodegenerative disease with no effective treatment or cure. Environmental enrichment has been used to slow…”
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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background by Jeremy S. Lum, Mikayla L. Brown, Natalie E. Farrawell, Luke McAlary, Diane Ly, Christen G. Chisholm, Josh Snow, Kara L. Vine, Tim Karl, Fabian Kreilaus, Lachlan E. McInnes, Sara Nikseresht, Paul S. Donnelly, Peter J. Crouch, Justin J. Yerbury

“…Abstract The synthetic copper-containing compound, CuATSM, has emerged as one of the most promising drug candidates developed for the treatment of amyotrophic…”
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Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis by Kreilaus, Fabian, Spiro, Adena S, Hannan, Anthony J, Garner, Brett, Jenner, Andrew M

“…Cholesterol has essential functions in neurological processes that require tight regulation of synthesis and metabolism. Perturbed cholesterol homeostasis has…”
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