Search Results - "Kreifeldt, Max"

Morphological and functional evidence of increased excitatory signaling in the prelimbic cortex during ethanol withdrawal by Varodayan, Florence P., Sidhu, Harpreet, Kreifeldt, Max, Roberto, Marisa, Contet, Candice

“…Excessive alcohol consumption in humans induces deficits in decision making and emotional processing, which indicates a dysfunction of the prefrontal cortex…”
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Brain-wide functional architecture remodeling by alcohol dependence and abstinence by Kimbrough, Adam, Lurie, Daniel J., Collazo, Andres, Kreifeldt, Max, Sidhu, Harpreet, Macedo, Giovana Camila, D’Esposito, Mark, Contet, Candice, George, Olivier

“…Alcohol abuse and alcohol dependence are key factors in the development of alcohol use disorder, which is a pervasive societal problem with substantial…”
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GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol by Herman, Melissa A., Sidhu, Harpreet, Stouffer, David G., Kreifeldt, Max, Le, David, Cates-Gatto, Chelsea, Munoz, Michaelanne B., Roberts, Amanda J., Parsons, Loren H., Roberto, Marisa, Wickman, Kevin, Slesingerc, Paul A., Contet, Candice

“…Significance G protein-gated inwardly rectifying potassium (GIRK) channels regulate neuronal excitability and can be activated by ethanol. The role of GIRK…”
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Prefrontal cortex glutamatergic adaptations in a mouse model of alcohol use disorder by Siddiqi, Mahum T., Podder, Dhruba, Pahng, Amanda R., Athanason, Alexandria C., Nadav, Tali, Cates-Gatto, Chelsea, Kreifeldt, Max, Contet, Candice, Roberts, Amanda J., Edwards, Scott, Roberto, Marisa, Varodayan, Florence P.

“…•Alcohol dependence enhanced AMPAR-mediated neurotransmission in the mPFC.•Alcohol dependence decreased mPFC GluA1 and GluA2 gene expression.•Alcohol…”
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Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization by Cohen, Ami, Whitfield, Timothy W, Kreifeldt, Max, Koebel, Pascale, Kieffer, Brigitte L, Contet, Candice, George, Olivier, Koob, George F

“…Dynorphins, endogenous opioid peptides that arise from the precursor protein prodynorphin (Pdyn), are hypothesized to be involved in the regulation of mood…”
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Affective Disturbances During Withdrawal from Chronic Intermittent Ethanol Inhalation in C57BL/6J and DBA/2J Male Mice by Sidhu, Harpreet, Kreifeldt, Max, Contet, Candice

“…Background Alcohol use disorders are characterized by a complex behavioral symptomatology, which includes the loss of control over alcohol consumption and the…”
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Modulation of locomotor activity by NMDA receptors in the nucleus accumbens core and shell regions of the rat by Pulvirenti, L, Berrier, R, Kreifeldt, M, Koob, G F

“…Two subdivisions of the nucleus accumbens (NAC), the core and the shell, have been recently identified on the basis of immunohistochemical differences and…”
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Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder by Macedo, Giovana C, Kreifeldt, Max, Goulding, Scott P, Okhuarobo, Agbonlahor, Sidhu, Harpreet, Contet, Candice

“…Alcohol use disorders can be driven by negative reinforcement. Alterations of the microtubule cytoskeleton have been associated with mood regulation in the…”
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Coloboma Hyperactive Mutant Mice Exhibit Regional and Transmitter‐Specific Deficits in Neurotransmission by Raber, Jacob, Mehta, Prashant P., Kreifeldt, Max, Parsons, Loren H., Weiss, Friebert, Bloom, Floyd E., Wilson, Michael C.

“…: The mouse mutant coloboma (Cm/+), which exhibits profound spontaneous hyperactivity and bears a deletion mutation on chromosome 2, including the gene…”
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The parasubthalamic nucleus refeeding ensemble delays feeding initiation and hastens water drinking by Dunning, Jeffery L, Lopez, Catherine, Krull, Colton, Kreifeldt, Max, Angelo, Maggie, Shu, Leeann, Ramakrishnan, Charu, Deisseroth, Karl, Contet, Candice

“…The parasubthalamic nucleus (PSTN) is activated by refeeding after food deprivation and several PSTN subpopulations have been shown to suppress feeding…”
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Chemogenetic Activation of Parasubthalamic nucleus Corticotropin‐Releasing Factor Neurons recapitulates Alcohol Withdrawal‐Related Behavioral Symptomatology by Okhuarobo, Agbonlahor, Kreifeldt, Max, de Macedo, Giovana Camila, Igbe, Ighodaro, Contet, Candice

“…Abstract only…”
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Differential control of alcohol consumption by neuronal subpopulations of the mouse parasubthalamic nucleus by Dunning, Jeffery L., Kreifeldt, Max, Okhuarobo, Agbonlahor, Lopez, Catherine, Krull, Colton, Angelo, Maggie, Mehta, Maya, Shah, Tanvi, Contet, Candice

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Central amygdala corticotropin-releasing factor neurons promote hyponeophagia but do not control alcohol drinking in mice by Kreifeldt, Max, Herman, Melissa A., Sidhu, Harpreet, Okhuarobo, Agbonlahor, Macedo, Giovana C., Shahryari, Roxana, Gandhi, Pauravi J., Roberto, Marisa, Contet, Candice

“…Corticotropin-releasing factor (CRF) signaling in the central nucleus of the amygdala (CeA) plays a critical role in rodent models of excessive alcohol…”
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Ethanol’s interaction with BK channel α subunit residue K361 does not mediate behavioral responses to alcohol in mice by Okhuarobo, Agbonlahor, Kreifeldt, Max, Gandhi, Pauravi J., Lopez, Catherine, Martinez, Briana, Fleck, Kiera, Bajo, Michal, Bhattacharyya, Pushpita, Dopico, Alex M., Roberto, Marisa, Roberts, Amanda J., Homanics, Gregg E., Contet, Candice

“…Large conductance potassium (BK) channels are among the most sensitive molecular targets of ethanol and genetic variations in the channel-forming α subunit…”
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BK Channel [beta]1 Subunit Contributes to Behavioral Adaptations Elicited by Chronic Intermittent Ethanol Exposure by Kreifeldt, Max, Cates-Gatto, Chelsea, Roberts, Amanda J, Contet, Candice

“…Background Large conductance, calcium- and voltage-activated potassium (BK) channels regulate neuronal excitability and neurotransmission. They can be directly…”
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BK Channel β1 Subunit Contributes to Behavioral Adaptations Elicited by Chronic Intermittent Ethanol Exposure by Kreifeldt, Max, Cates-Gatto, Chelsea, Roberts, Amanda J., Contet, Candice

“…Background Large conductance, calcium‐ and voltage‐activated potassium (BK) channels regulate neuronal excitability and neurotransmission. They can be directly…”
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BK Channel β 1 Subunit Contributes to Behavioral Adaptations Elicited by Chronic Intermittent Ethanol Exposure by Kreifeldt, Max, Cates‐Gatto, Chelsea, Roberts, Amanda J., Contet, Candice

“…Background Large conductance, calcium- and voltage-activated potassium (BK) channels regulate neuronal excitability and neurotransmission. They can be directly…”
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MeCP2 regulates ethanol sensitivity and intake by Repunte-Canonigo, Vez, Chen, Jihuan, Lefebvre, Celine, Kawamura, Tomoya, Kreifeldt, Max, Basson, Oan, Roberts, Amanda J., Sanna, Pietro Paolo

“…We have investigated the expression of chromatin‐regulating genes in the prefrontal cortex and in the shell subdivision of the nucleus accumbens during…”
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Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice by Xu, Jun, Ma, Hsiao-Yen, Liu, Xiao, Rosenthal, Sara, Baglieri, Jacopo, McCubbin, Ryan, Sun, Mengxi, Koyama, Yukinori, Geoffroy, Cedric G, Saijo, Kaoru, Shang, Linshan, Nishio, Takahiro, Maricic, Igor, Kreifeldt, Max, Kusumanchi, Praveen, Roberts, Amanda, Zheng, Binhai, Kumar, Vipin, Zengler, Karsten, Pizzo, Donald P, Hosseini, Mojgan, Contet, Candice, Glass, Christopher K, Liangpunsakul, Suthat, Tsukamoto, Hidekazu, Gao, Bin, Karin, Michael, Brenner, David A, Koob, George F, Kisseleva, Tatiana

“…Chronic alcohol abuse has a detrimental effect on the brain and liver. There is no effective treatment for these patients, and the mechanism underlying alcohol…”
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BK channel β1 and β4 auxiliary subunits exert opposite influences on escalated ethanol drinking in dependent mice by Kreifeldt, Max, Le, David, Treistman, Steven N, Koob, George F, Contet, Candice

“…Large conductance calcium-activated potassium (BK) channels play a key role in the control of neuronal activity. Ethanol is a potent activator of BK channel…”
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