Search Results - "Krebs, Jutta"
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Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes
Published in EMBO molecular medicine (01-07-2018)“…The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein‐coupled…”
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2
Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling
Published in Proceedings of the National Academy of Sciences - PNAS (16-09-2014)“…Significance In failing hearts, norepinephrine (NE) net release and endothelin-1 (ET1) levels are increased. ET1 receptor antagonists were successfully used in…”
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3
Phosphorylation of T107 by CamKIIδ Regulates the Detoxification Efficiency and Proteomic Integrity of Glyoxalase 1
Published in Cell reports (Cambridge) (22-09-2020)“…The glyoxalase system is a highly conserved and ubiquitously expressed enzyme system, which is responsible for the detoxification of methylglyoxal (MG), a…”
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4
Local injection of stem cell factor (SCF) improves myocardial homing of systemically delivered c-kit + bone marrow-derived stem cells
Published in Cardiovascular research (01-01-2008)“…Aims Recent studies have shown that stem cell therapy may alleviate the detrimental effects of myocardial infarction. Yet, most of these reports observed only…”
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5
Differential expression of cardiac neurotrophic factors and sympathetic nerve ending abnormalities within the failing heart
Published in Journal of molecular and cellular cardiology (01-02-2008)“…Abstract In congestive heart failure (CHF), cardiac sympathetic nerve endings transdifferentiate from a balanced norepinephrine (NE) storage/release/uptake…”
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6
Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT
Published in Journal of translational medicine (06-06-2012)“…Previous experimental studies concluded that stem cells (SC) may exert their beneficial effects on the ischemic heart by paracrine activation of antiapoptotic…”
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7
Inflammation leads through PGE / EP 3 signaling to HDAC 5/ MEF 2‐dependent transcription in cardiac myocytes
Published in EMBO molecular medicine (01-07-2018)“…The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein‐coupled…”
Get full text
Journal Article -
8
Inflammation leads through PGE/EP 3 signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes
Published in EMBO molecular medicine (01-07-2018)“…The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein-coupled…”
Get full text
Journal Article -
9
Cardiac remodeling is not modulated by overexpression of muscle LIM protein (MLP)
Published in Basic research in cardiology (01-05-2012)“…Muscle LIM protein (MLP) has been proposed to be a central player in the pathogenesis of heart muscle disease. In line with this notion, the homozygous loss of…”
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10
Cyclic AMP represses pathological MEF2 activation by myocyte-specific hypo-phosphorylation of HDAC5
Published in Journal of molecular and cellular cardiology (01-08-2020)“…Class IIa histone deacetylases (HDACs) critically regulate cardiac function through the repression of the activity of myocyte enhancer factor 2…”
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11
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway
Published in Nature medicine (01-01-2018)“…A proteolytically derived fragment of the epigenetic regulator HDAC4 protects the heart through transcriptional repression of the hexosamine biosynthetic…”
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