Search Results - "Krebs, Fred C."

Manipulation of Oxidative Stress Responses by Non-Thermal Plasma to Treat Herpes Simplex Virus Type 1 Infection and Disease by Sutter, Julia, Bruggeman, Peter J, Wigdahl, Brian, Krebs, Fred C, Miller, Vandana

“…Herpes simplex virus type 1 (HSV-1) is a contagious pathogen with a large global footprint, due to its ability to cause lifelong infection in patients. Current…”
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Non-Thermal Plasma Reduces HSV-1 Infection of and Replication in HaCaT Keratinocytes In Vitro by Sutter, Julia, Brettschneider, Jascha, Wigdahl, Brian, Bruggeman, Peter J, Krebs, Fred C, Miller, Vandana

“…Herpes simplex virus type 1 (HSV-1) is a lifelong pathogen characterized by asymptomatic latent infection in the trigeminal ganglia (TG), with periodic…”
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Non-thermal plasma modulates cellular markers associated with immunogenicity in a model of latent HIV-1 infection by Mohamed, Hager, Clemen, Ramona, Freund, Eric, Lackmann, Jan-Wilm, Wende, Kristian, Connors, Jennifer, Haddad, Elias K, Dampier, Will, Wigdahl, Brian, Miller, Vandana, Bekeschus, Sander, Krebs, Fred C

“…Effective control of infection by human immunodeficiency virus type 1 (HIV-1), the causative agent of the acquired immunodeficiency syndrome (AIDS), requires…”
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Combinatorial Approaches to the Prevention and Treatment of HIV-1 Infection by PIRRONE, Vanessa, THAKKAR, Nina, JACOBSON, Jeffrey M, WIGDAHL, Brian, KREBS, Fred C

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Nonthermal plasma as part of a novel strategy for vaccination by Mohamed, Hager, Esposito, Rita A., Kutzler, Michele A., Wigdahl, Brian, Krebs, Fred C., Miller, Vandana

“…Vaccination has been one of the most effective health intervention mechanisms to reduce morbidity and mortality associated with infectious diseases. Vaccines…”
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The Evolution of Dendritic Cell Immunotherapy against HIV-1 Infection: Improvements and Outlook by Wigdahl, Brian, Jennings, Stephen R., Miller, Vandana, Rose, William Nicholas, Krebs, Fred C.

“…Dendritic cells (DC) are key phagocytic cells that play crucial roles in both the innate and adaptive immune responses against the human immunodeficiency virus…”
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Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid by Kortagere, Sandhya, Madani, Navid, Mankowski, Marie K., Schön, Arne, Zentner, Isaac, Swaminathan, Gokul, Princiotto, Amy, Anthony, Kevin, Oza, Apara, Sierra, Luz-Jeannette, Passic, Shendra R., Wang, Xiaozhao, Jones, David M., Stavale, Eric, Krebs, Fred C., Martín-García, Julio, Freire, Ernesto, Ptak, Roger G., Sodroski, Joseph, Cocklin, Simon, Smith, Amos B.

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GSH Modification as a Marker for Plasma Source and Biological Response Comparison to Plasma Treatment by Ranieri, Pietro, Mohamed, Hager, Myers, Brayden, Dobossy, Leah, Beyries, Keely, Trosan, Duncan, Krebs, Fred C., Miller, Vandana, Stapelmann, Katharina

“…This study investigated the use of glutathione as a marker to establish a correlation between plasma parameters and the resultant liquid chemistry from two…”
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Immunomodulatory Effects of Non-Thermal Plasma in a Model for Latent HIV-1 Infection: Implications for an HIV-1-Specific Immunotherapy by Mohamed, Hager, Berman, Rachel, Connors, Jennifer, Haddad, Elias K, Miller, Vandana, Nonnemacher, Michael R, Dampier, Will, Wigdahl, Brian, Krebs, Fred C

“…In people living with HIV-1 (PLWH), antiretroviral therapy (ART) eventually becomes necessary to suppress the emergence of human immunodeficiency virus type 1…”
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Antiviral Breadth and Combination Potential of Peptide Triazole HIV-1 Entry Inhibitors by McFadden, Karyn, Fletcher, Patricia, Rossi, Fiorella, Kantharaju, Umashankara, Muddagowda, Pirrone, Vanessa, Rajagopal, Srivats, Gopi, Hosahudya, Krebs, Fred C, Martin-Garcia, Julio, Shattock, Robin J, Chaiken, Irwin

“…The first stage of human immunodeficiency virus type 1 (HIV-1) infection involves the fusion of viral and host cellular membranes mediated by viral envelope…”
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Alkylated Porphyrins Have Broad Antiviral Activity against Hepadnaviruses, Flaviviruses, Filoviruses, and Arenaviruses by Guo, Haitao, Pan, Xiaoben, Mao, Richeng, Zhang, Xianchao, Wang, Lijuan, Lu, Xuanyong, Chang, Jinhong, Guo, Ju-Tao, Passic, Shendra, Krebs, Fred C, Wigdahl, Brian, Warren, Travis K, Retterer, Cary J, Bavari, Sina, Xu, Xiaodong, Cuconati, Andrea, Block, Timothy M

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The rise and fall of polyanionic inhibitors of the human immunodeficiency virus type 1 by Pirrone, Vanessa, Wigdahl, Brian, Krebs, Fred C.

“…Infection by the human immunodeficiency virus type 1 (HIV-1) is an ordered, multistep process involving binding and entry, reverse transcription, integration,…”
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Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1 by Rosa Borges, Andrew, Wieczorek, Lindsay, Johnson, Benitra, Benesi, Alan J, Brown, Bruce K, Kensinger, Richard D, Krebs, Fred C, Wigdahl, Brian, Blumenthal, Robert, Puri, Anu, McCutchan, Francine E, Birx, Deborah L, Polonis, Victoria R, Schengrund, Cara-Lynne

“…Abstract Specific glycosphingolipids (GSL), found on the surface of target immune cells, are recognized as alternate cell surface receptors by the human…”
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Application and removal of polyanionic microbicide compounds enhances subsequent infection by HIV-1 by Pirrone, Vanessa, Passic, Shendra, Wigdahl, Brian, Krebs, Fred C

“…Continued efforts are being directed toward the development of microbicides that will be used to reduce or eliminate the risk of HIV-1 sexual transmission…”
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Specific Interactions between the Viral Coreceptor CXCR4 and the Biguanide-Based Compound NB325 Mediate Inhibition of Human Immunodeficiency Virus Type 1 Infection by THAKKAR, Nina, PIRRONE, Vanessa, PASSIC, Shendra, WEI ZHU, KHOLODOVYCH, Vladyslav, WELSH, William, RANDO, Robert F, LABIB, Mohamed E, WIGDAHL, Brian, KREBS, Fred C

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Persistent Interactions between Biguanide-Based Compound NB325 and CXCR4 Result in Prolonged Inhibition of Human Immunodeficiency Virus Type 1 Infection by THAKKAR, Nina, PIRRONE, Vanessa, KREBS, Fred C, PASSIC, Shendra, KEOGAN, Shawn, WEI ZHU, KHOLODOVYCH, Vladyslav, WELSH, William, RANDO, Robert, LABIB, Mohamed, WIGDAHL, Brian

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Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1 by Krebs, Fred C., Miller, Shendra R., Ferguson, Mary Lee, Labib, Mohamed, Rando, Robert F., Wigdahl, Brian

“…Polyhexamethylene biguanide (PHMB) is a polybiguanide (PBG) oligomer with antimicrobial activity that is used extensively and safely as a disinfectant. The…”
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Novel Polysulfated Galactose-Derivatized Dendrimers as Binding Antagonists of Human Immunodeficiency Virus Type 1 Infection by KENSINGER, Richard D, CATALONE, Bradley J, KREBS, Fred C, WIGDAHL, Brian, SCHENGRUND, Cara-Lynne

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Mouse Model of Cervicovaginal Toxicity and Inflammation for Preclinical Evaluation of Topical Vaginal Microbicides by CATALONE, Bradley J, KISH-CATALONE, Tina M, BUDGEON, Lynn R, NEELY, Elizabeth B, FERGUSON, Maelee, KREBS, Fred C, HOWETT, Mary K, LABIB, Mohamed, RANDO, Robert, WIGDAHL, Brian

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Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences by Williams, Jean, James, Tony, Jacobson, Jeffrey M., Szep, Zsofia, Wigdahl, Brian, Krebs, Fred C., Passic, Shendra, Kercher, Katherine, Zhong, Wen, Pirrone, Vanessa, Nonnemacher, Michael R., Aiamkitsumrit, Benjamas, Dampier, Will, Antell, Gregory C., Liu, Yucheng

“…Vpr is an HIV-1 accessory protein that plays numerous roles during viral replication, and some of which are cell type dependent. To test the hypothesis that…”
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