Search Results - "Kreżel, W"

Estrous cycle effects on behavior of C57BL/6J and BALB/cByJ female mice: implications for phenotyping strategies by Meziane, H., Ouagazzal, A.‐M., Aubert, L., Wietrzych, M., Krezel, W.

“…Systematic behavioral phenotyping of genetically modified mice is a powerful method with which to identify the molecular factors implicated in control of…”
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Differential expression of retinoid receptors in the adult mouse central nervous system by Kreżel, W, Kastner, P, Chambon, P

“…The immunocytochemical distribution of retinoid receptors has been analysed in the mouse adult central nervous system. All retinoic acid receptors ( α, β and…”
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Effects of social crowding on emotionality and expression of hippocampal nociceptin/orphanin FQ system transcripts in mice by Reiss, D., Wolter-Sutter, A., Krezel, W., Ouagazzal, A.-M.

“…The novel nociceptin/orphanin FQ (N/OFQ) system was proposed to be an important component of neural circuits involved in stress-coping behaviour and fear. This…”
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Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development by Kastner, P, Mark, M, Ghyselinck, N, Krezel, W, Dupé, V, Grondona, J M, Chambon, P

“…We describe here the analysis of congenital malformations in compound mutant fetuses bearing null alleles in one RXR (alpha, beta or gamma) and one RAR (alpha,…”
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RXRγ Null Mice are Apparently Normal and Compound RXRα +/-/RXRβ -/-/RXRγ -/- Mutant Mice are Viable by Krężel, Wojciech, Dupé, Valerie, Mark, Manuel, Dierich, Andrée, Kastner, Philippe, Chambon, Pierre

“…The RXRγ (RXR, retinoid X receptor) gene was disrupted in the mouse. Homozygous mutant mice developed normally and were indistinguishable from their RXRγ +/-…”
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Abnormal spermatogenesis in RXR beta mutant mice by Kastner, P, Mark, M, Leid, M, Gansmuller, A, Chin, W, Grondona, J M, Décimo, D, Krezel, W, Dierich, A, Chambon, P

“…We have generated mouse lines in which the RXR beta gene was disrupted by homologous recombination. Approximately 50% of the RXR beta homozygous mutants died…”
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Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha by Mascrez, B, Mark, M, Krezel, W, Dupé, V, LeMeur, M, Ghyselinck, N B, Chambon, P

“…We have engineered a mouse mutation that specifically deletes most of the RXR alpha N-terminal A/B region, which includes the activation function AF-1 and…”
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Compensatory mechanism of motor defect in SOD1 transgenic mice by overactivation of striatal cholinergic neurons by Azzouz, M, Krezel, W, Dollé, P, Vodouhe, C, Warter, J M, Poindron, P, Borg, J

“…EXPRESSION of a mutant superoxide dismutase 1 (SOD1) gene in transgenic mice induces a gradual degeneration of cholinergic motor neurons in the spinal cord,…”
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Retinoic Acid Receptor Controls Development of Striatonigral Projection Neurons through FGF-Dependent and Meis1-Dependent Mechanisms by Rataj-Baniowska, M., Niewiadomska-Cimicka, A., Paschaki, M., Szyszka-Niagolov, M., Carramolino, L., Torres, M., Dolle, P., Krezel, W.

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Retinoic acid deficiency impairs the vestibular function by Romand, Raymond, Krezel, Wojciech, Beraneck, Mathieu, Cammas, Laura, Fraulob, Valérie, Messaddeq, Nadia, Kessler, Pascal, Hashino, Eri, Dollé, Pascal

“…The retinaldehyde dehydrogenase 3 (Raldh3) gene encodes a major retinoic acid synthesizing enzyme and is highly expressed in the inner ear during…”
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Knockout of ERK1 MAP Kinase Enhances Synaptic Plasticity in the Striatum and Facilitates Striatal-Mediated Learning and Memory by Mazzucchelli, Cristina, Vantaggiato, Chiara, Ciamei, Alessandro, Fasano, Stefania, Pakhotin, Pavel, Krezel, Wojciech, Welzl, Hans, Wolfer, David P, Pagès, Gilles, Valverde, Olga, Marowsky, Anne, Porrazzo, Annamaria, Orban, Paul C, Maldonado, Rafael, Ehrengruber, Markus U, Cestari, Vincenzo, Lipp, Hans-Peter, Chapman, Paul F, Pouysségur, Jacques, Brambilla, Riccardo

“…Extracellular signal-regulated kinases (ERK1 and 2) are synaptic signaling components necessary for several forms of learning. In mice lacking ERK1, we observe…”
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Increased Anxiety and Synaptic Plasticity in Estrogen Receptor β-Deficient Mice by Krężel, Wojciech, Dupont, Sonia, Krust, Andrée, Chambon, Pierre, Chapman, Paul F.

“…Estrogens are powerful modulators of neuronal physiology and in humans may affect a broad range of functions, including reproductive, emotional, and cognitive…”
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Working memory deficits in retinoid X receptor γ-deficient mice by WIETRZYCH, Marta, MEZIANE, Hamid, SUTLER, Anne, GHYSELINCK, Norbert, CHAPMAN, Paul F, CHAMBON, Pierre, KREZEL, Wojciech

“…Retinoid signaling has been recently shown to be required for mnemonic functions in rodents. To dissect the behavioral and molecular mechanisms involved in…”
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Impaired Locomotion and Dopamine Signaling in Retinoid Receptor Mutant Mice by Krȩżel, Wojciech, Ghyselinck, Norbert, Samad, Tarek A., Dupé, Valérie, Kastner, Philippe, Borrelli, Emiliana, Chambon, Pierre

“…In the adult mouse, single and compound null mutations in the genes for retinoic acid receptor β and retinoid X receptors β and γ resulted in locomotor defects…”
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Regulation of Dopaminergic Pathways by Retinoids: Activation of the D2 Receptor Promoter by Members of the Retinoic Acid Receptor-Retinoid X Receptor Family by Samad, T A, Krezel, W, Chambon, P, Borrelli, E

“…Dopamine is a neuromodulator involved in the control of key physiological functions. Dopamine-dependent signal transduction is activated through the…”
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Effects of Rexinoids on Thyrotrope Function and the Hypothalamic-Pituitary-Thyroid Axis by Sharma, Vibha, Hays, William R, Wood, William M, Pugazhenthi, Umarani, St. Germain, Donald L, Bianco, Antonio C, Krezel, Wojciech, Chambon, Pierre, Haugen, Bryan R

“…Retinoid X receptor (RXR)-selective retinoids (rexinoids) can cause central hypothyroidism in humans, and this effect has been confirmed in rodent models. In…”
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Retinoid X Receptor γ-Deficient Mice Have Increased Skeletal Muscle Lipoprotein Lipase Activity and Less Weight Gain when Fed a High-Fat Diet by Haugen, Bryan R, Jensen, Dalan R, Sharma, Vibha, Pulawa, Leslie K, Hays, William R, Krezel, Wojciech, Chambon, Pierre, Eckel, Robert H

“…Retinoids, derivatives of vitamin A, induce hypertriglyceridemia through decreased clearance of very low-density lipoprotein by a lipoprotein lipase…”
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Thyroid hormone resistance and increased metabolic rate in the RXR-gamma-deficient mouse by Brown, N S, Smart, A, Sharma, V, Brinkmeier, M L, Greenlee, L, Camper, S A, Jensen, D R, Eckel, R H, Krezel, W, Chambon, P, Haugen, B R

“…Vitamin A and retinoids affect pituitary-thyroid function through suppression of serum thyroid-stimulating hormone (TSH) levels and TSH-beta subunit gene…”
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Aberrant growth plate development in VDR/RXR gamma double null mutant mice by Yagishita, N, Yamamoto, Y, Yoshizawa, T, Sekine, K, Uematsu, Y, Murayama, H, Nagai, Y, Krezel, W, Chambon, P, Matsumoto, T, Kato, S

“…VDR forms heterodimers with one of three RXRs, RXR alpha, RXR beta, and RXR gamma, and it is thought that RXR ligands can also modulate the trans-activation…”
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B80 BEHAVIOURAL ADAPTATION TO CHRONIC SOCIAL STRESS: ROLE OF HIPPOCAMPAL N/OFQ PEPTIDE by Reiss, D., Sutter, A., Krezel, W., Ouagazzal, A.M.

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