Search Results - "Krawetz, R.J."

Lubricin/Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro by Iqbal, S.M., Leonard, C., C. Regmi, S., De Rantere, D., Tailor, P., Ren, G., Ishida, H., Hsu, CY, Abubacker, S., Pang, D. SJ, T. Salo, P., Vogel, H.J., Hart, D.A., Waterhouse, C.C., Jay, G.D, Schmidt, T.A., Krawetz, R.J.

“…Proteoglycan 4 (PRG4/lubricin) is secreted by cells that reside in articular cartilage and line the synovial joint. Lubricin may play a role in modulating…”
Get full text

Cytokine network analysis of a youth injury cohort reveals a conserved joint injury and OA inflammatory signature that are potential biomarkers of MRI-defined OA by Ren, G, Whittaker, J.L, Emery, C.A, Krawetz, R.J

Get full text

Endogenous PRRX1+ progenitors are present after full thickness cartilage injury but do not directly contribute to fibrocartilage or subchondral bone tissues during the repair process by Jablonski, C.L, Leonard, C, Krawetz, R.J

Get full text

Synovial mesenchymal stem cells from “super-healer” mice directly contribute to articular cartilage regeneration by Jablonski, C.L, Mak, J, Leonard, C, Stevens, K.M, Colarusso, P, Krawetz, R.J

Get full text

Embryonic stem cell therapy improves bone quality in a model of impaired fracture healing in the mouse; tracked temporally using in vivo micro-CT by Taiani, J.T, Buie, H.R, Campbell, G.M, Manske, S.L, Krawetz, R.J, Rancourt, D.E, Boyd, S.K, Matyas, J.R

“…Abstract In the current study, we used an estrogen-deficient mouse model of osteoporosis to test the efficacy of a cell-generated bone tissue construct for…”
Get full text

Blood serum to diagnose osteoarthritis – biomarkers and machine learning by Heard, B.J, Rosvold, J.M, Fritzler, M.J, El-Gabalawy, H, Wiley, J.P, Krawetz, R.J

Get full text

CCL22 is a potential bio-marker for osteoarthritic pain and cartilage degeneration by Ren, G, Railton, P, Whittaker, J.L, Leonard, C, Salo, P.T, Laudon, J, McAllister, J, Wiley, J.P, Powell, J, Emery, C.A, Krawetz, R.J

Get full text

88 GENOME WIDE EXPRESSION PROFILING OF NORMAL, RHEUMATOID AND OSTEOARTHRITIC SYNOVIAL STEM CELLS by Krawetz, R.J, Lee, P.S, Hart, D.A, Frank, C.B

Get full text

Monocyte chemotactic protein-1 regulates the chondrogenic activity of synovial mesenchymal progenitor cells by Harris, Q, Seto, J, O'Biren, K, Lee, P, Kondo, C, Heard, B, Hart, D, Krawetz, R.J

Get full text

Precision medicine, big data and machine learning in OA by Krawetz, R.J.

Get full text

Development and characterization of a novel non-surgical mouse model of intervertebral disc degeneration by Masson, A.O., Corpuz, K., Salo, P., Krawetz, R.J.

Get full text

The effect of in vivo chondrocyte depletion on the structural and functional properties of murine articular cartilage by Masson, A.O., Corpuz, J.M., Edwards, W.B., Krawetz, R.J.

Get full text

A prospective study of serum cytokine profile in individuals at risk of post-traumatic osteoarthritis by Ren, G., Whittaker, J.L., Emery, C.A., Krawetz, R.J.

Get full text

Investigating the role of in vivo cell cycle activation within mesenchymal stem cells in the regenerative potential of articular cartilage after injury by Masson, A.O., Underhill, T.M., Edwards, W.B., Krawetz, R.J.

Get full text

Enhancing articular cartilage regeneration by modulating the cell cycle within mesenchymal progenitors by Masson, A.O., Besler, B.A., Young, D., Dufour, A., Edwards, W.B., Underhill, T.M., Krawetz, R.J.

Get full text

Serum cartilage oligomeric matrix protein (COMP) expression in individuals who sustained a youth sport-related intra-articular knee injury 3–10 years previously and uninjured matched controls by Laudon, J., Whittaker, J.L., Ren, G., Jaremko, J.L., Emery, C.A., Krawetz, R.J.

“…This study investigates the relationship between a youth sport-related intra-articular knee injury and cartilage oligomeric matrix protein (COMP), a biomarker…”
Get full text

Zinc finger protein-440 promotes cartilage degenerative mechanisms in human facet and knee osteoarthritis chondrocytes by Nakamura, A., Rampersaud, Y.R., Sundararajan, K., Nakamura, S., Wu, B., Matip, E., Haroon, N., Krawetz, R.J., Rossomacha, E., Gandhi, R., Kotlyar, M., Rockel, J.S., Jurisica, I., Kapoor, M.

“…To investigate the role of zinc finger protein 440 (ZNF440) in the pathophysiology of cartilage degeneration during facet joint (FJ) and knee osteoarthritis…”
Get full text

CCL22 is a biomarker of cartilage injury and plays a functional role in chondrocyte apoptosis by Ren, G., Whittaker, J.L., Leonard, C., De Rantere, D., Pang, D.S.J., Salo, P., Fritzler, M., Kapoor, M., de Koning, A.P.J., Jaremko, J.L., Emery, C.A., Krawetz, R.J.

“…Osteoarthritis (OA) is one of the leading causes of disability worldwide. Previous history of knee injury is a significant risk factor for OA. It has been…”
Get full text