Search Results - "Krawczyk, Paweł S."
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Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s
Published in Cell (06-09-2018)“…LINE-1 retrotransposition is tightly restricted by layers of regulatory control, with epigenetic pathways being the best characterized. Looking at…”
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2
Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae
Published in Nature communications (16-08-2021)“…The polyadenosine tail (poly[A]-tail) is a universal modification of eukaryotic messenger RNAs (mRNAs) and non-coding RNAs (ncRNAs). In budding yeast,…”
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3
Structure-functional characterization of Lactococcus AbiA phage defense system
Published in Nucleic acids research (08-05-2024)“…Bacterial reverse transcriptases (RTs) are a large and diverse enzyme family. AbiA, AbiK and Abi-P2 are abortive infection system (Abi) RTs that mediate…”
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4
Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C
Published in Nature communications (27-04-2020)“…TENT5C is a non-canonical cytoplasmic poly(A) polymerase highly expressed by activated B cells to suppress their proliferation. Here we measure the global…”
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Cytoplasmic polyadenylation by TENT5A is required for proper bone formation
Published in Cell reports (Cambridge) (20-04-2021)“…Osteoblasts orchestrate bone formation through the secretion of type I collagen and other constituents of the matrix on which hydroxyapatite crystals…”
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Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae
Published in Genes & development (01-09-2021)“…Biogenesis of most eukaryotic mRNAs involves the addition of an untemplated polyadenosine (pA) tail by the cleavage and polyadenylation machinery. The pA tail,…”
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TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals
Published in Science advances (16-11-2022)“…Innate immunity is the first line of host defense against pathogens. Here, through global transcriptome and proteome analyses, we uncover that newly described…”
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Modeling of mRNA deadenylation rates reveal a complex relationship between mRNA deadenylation and decay
Published in The EMBO journal (11-10-2024)“…Complete cytoplasmic polyadenosine tail (polyA-tail) deadenylation is thought to be essential for initiating mRNA decapping and subsequent degradation. To…”
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PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures
Published in Nucleic acids research (06-04-2018)“…Abstract Plasmids are mobile genetics elements that play an important role in the environmental adaptation of microorganisms. Although plasmids are usually…”
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Comparative analysis of deep sequenced methanogenic communities: identification of microorganisms responsible for methane production
Published in Microbial cell factories (20-12-2018)“…Although interactions between microorganisms involved in biogas production are largely uncharted, it is commonly accepted that methanogenic Archaea are…”
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Physiological and Metagenomic Analyses of Microbial Mats Involved in Self-Purification of Mine Waters Contaminated with Heavy Metals
Published in Frontiers in microbiology (10-08-2016)“…Two microbial mats found inside two old (gold and uranium) mines in Zloty Stok and Kowary located in SW Poland seem to form a natural barrier that traps heavy…”
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12
Adaptation of Methanogenic Inocula to Anaerobic Digestion of Maize Silage
Published in Frontiers in microbiology (28-09-2017)“…A well-balanced microbial consortium is crucial for efficient biogas production. In turn, one of a major factor that influence on the structure of anaerobic…”
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13
Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system
Published in PloS one (28-03-2018)“…Deciphering a function of a given protein requires investigating various biological aspects. Usually, the protein of interest is expressed with a fusion tag…”
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Analysis of the Genome and Mobilome of a Dissimilatory Arsenate Reducing Aeromonas sp. O23A Reveals Multiple Mechanisms for Heavy Metal Resistance and Metabolism
Published in Frontiers in microbiology (29-05-2017)“…spp. are among the most ubiquitous microorganisms, as they have been isolated from different environmental niches including waters, soil, as well as wounds and…”
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15
Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons
Published in The Journal of neuroscience (06-04-2011)“…The pattern of dendritic branching, together with the density of synapses and receptor composition, defines the electrical properties of a neuron. The…”
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A new strategy for gene targeting and functional proteomics using the DT40 cell line
Published in Nucleic acids research (01-09-2013)“…DT40 cells derived from chicken B lymphocytes exhibit exceptionally high homologous recombination rates. Therefore, they can be used as a convenient tool and…”
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Genome Sequence of Flavor-Producing Yeast Saprochaete suaveolens NRRL Y-17571
Published in Microbiology resource announcements (28-02-2019)“…Saprochaete suaveolens is an ascomycetous yeast that produces a range of fruity flavors and fragrances. Here, we report the high-contiguity genome sequence of…”
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