Search Results - "Kraut, H."
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Phase I Trial of Lenalidomide and CCI-779 in Patients With Relapsed Multiple Myeloma: Evidence for Lenalidomide–CCI-779 Interaction via P-Glycoprotein
Published in Journal of clinical oncology (01-09-2011)“…Multiple myeloma (MM) is an incurable plasma-cell neoplasm for which most treatments involve a therapeutic agent combined with dexamethasone. The preclinical…”
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2
Flavopiridol, Fludarabine, and Rituximab in Mantle Cell Lymphoma and Indolent B-Cell Lymphoproliferative Disorders
Published in Journal of clinical oncology (20-01-2010)“…Flavopiridol downmodulates antiapoptotic proteins associated with resistance to fludarabine and rituximab and is effective against p53-mutated chronic…”
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3
NCCN Guidelines Insights: Hematopoietic Growth Factors, Version 1.2020
Published in Journal of the National Comprehensive Cancer Network (01-01-2020)“…Management of febrile neutropenia (FN) is an integral part of supportive care for patients undergoing cancer treatment. The NCCN Guidelines for Hematopoietic…”
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4
An evaluation of ciclosporin and corticosteroids individually as adjuncts to plasma exchange in the treatment of thrombotic thrombocytopenic purpura
Published in British journal of haematology (01-01-2007)“…Summary We present the results of two consecutively performed cohort studies that evaluated the clinical effects of corticosteroids or ciclosporin as an…”
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5
Bleeding and bruising: a diagnostic work-up
Published in American family physician (15-04-2008)“…Primary care physicians are often asked about easy bruising, excessive bleeding, or risk of bleeding before surgery. A thorough history, including a family…”
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6
Phase II trial of oxaliplatin, leucovorin and fluorouracil in patients with advanced carcinoma of the esophagus
Published in Annals of oncology (01-08-2005)“…Background: The aim of the study was to evaluate the efficacy and tolerability of the combination of oxaliplatin, fluorouracil and leucovorin in patients with…”
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Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia
Published in Blood (15-01-2003)“…Overexpression of Bcl-2 is a potential mechanism for chemoresistance in acute leukemia and has been associated with unfavorable clinical outcome. We…”
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8
Surgical interventions in a cohort of patients with haemophilia A and inhibitors: an experiential retrospective chart review
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-09-2007)“…Strategies for the management of perioperative bleeding in patients with haemophilia and inhibitors have evolved rapidly as a result of the development of the…”
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9
A Phase I and Pharmacokinetic Study of Weekly Oxaliplatin Followed by Paclitaxel in Patients with Solid Tumors
Published in Clinical cancer research (01-06-2008)“…Purpose: Oxaliplatin and paclitaxel are widely used in treating solid tumors. We designed a phase I study with the purpose of determining the maximal tolerated…”
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10
Clinical manifestations and infectious complications of hairy-cell leukaemia
Published in Best practice & research. Clinical haematology (01-03-2003)“…Hairy-cell leukaemia is an indolent lymphoproliferative malignancy characterized by infiltration of the bone marrow, liver, spleen, and occasionally lymph…”
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Experience With Pre-procedural Hemostatic Medications versus Platelet Transfusion in Patients With Platelet Storage Pool Deficiency
Published in Journal of pharmacy practice (01-12-2023)“…Background Storage pool deficiency (SPD) is a rare bleeding disorder characterized by reduction in the number of delta granules within platelets, interfering…”
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Minimal SARS-CoV-2 Transmission After Implementation of a Comprehensive Mitigation Strategy at a School - New Jersey, August 20-November 27, 2020
Published in MMWR. Morbidity and mortality weekly report (19-03-2021)“…During fall 2020, many U.S. kindergarten through grade 12 (K-12) schools closed campuses and instituted remote learning to limit in-school transmission of…”
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Myocardial ischemia and right ventricular dysfunction in adult patients with sickle cell disease
Published in Haematologica (Roma) (01-10-2006)“…Division of Cardiovascular Medicine, The Ohio State University 473 W. 12th Avenue, Suite 200, Columbus, OH 43210, USA. Raman.1@osu.edu BACKGROUND AND…”
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14
Phase II study of dolastatin-10 as first-line treatment for advanced colorectal cancer
Published in American journal of clinical oncology (01-10-2002)“…Dolastatin-10 is a potent inhibitor of microtubule assembly derived from the sea hare, which displayed significant antitumor activity in preclinical models. We…”
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A Case Report of Siblings with Dystonia: A Potential Link Between DYT11 Mutation and Platelet Dysfunction
Published in Neurology India (01-01-2022)“…Myoclonus-dystonia syndrome (MDS) is an autosomal dominant disorder due to a mutated epsilon-sarcoglycan gene (SGCE) at the dystonia 11 (DYT11) locus on…”
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16
Cancer- and chemotherapy-induced anemia
Published in Journal of the National Comprehensive Cancer Network (01-05-2012)“…Anemia is prevalent in 30% to 90% of patients with cancer. Anemia can be corrected through either treating the underlying cause or providing supportive care…”
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Extended Use of Intravenous Bisphosphonate Therapy for the Prevention of Skeletal Complications in Patients with Cancer
Published in Cancer investigation (13-11-2009)“…ABSTRACT Purpose: To evaluate the incidence of skeletal complications in patients with multiple myeloma, and metastatic breast, prostate, or lung cancers, when…”
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18
Long-term follow-up of patients with hairy cell leukemia after treatment with 2'-deoxycoformycin
Published in Blood (15-12-1994)“…Twenty-four patients with advanced hairy cell leukemia treated with 2'-deoxycoformycin (dCF) were studied after achieving complete remission to determine the…”
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Evaluation of topotecan in resistant and relapsing multiple myeloma: a Southwest Oncology Group study
Published in Journal of clinical oncology (01-02-1998)“…Topotecan is a topoisomerase I inhibitor with antitumor activity against hematologic and solid tumor malignancies. We evaluated its activity in refractory and…”
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A phase I trial of flavopiridol in relapsed multiple myeloma
Published in Cancer chemotherapy and pharmacology (01-02-2014)“…Purpose Flavopiridol is primarily a cyclin-dependent kinase-9 inhibitor, and we performed a dose escalation trial to determine the maximum tolerated dose and…”
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