Search Results - "Krauss, Stefan"

Wnt/beta-catenin signaling and small molecule inhibitors by Voronkov, Andrey, Krauss, Stefan

“…Wnt/β-catenin signaling is a branch of a functional network that dates back to the first metazoans and it is involved in a broad range of biological systems…”
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Tankyrases: structure, function and therapeutic implications in cancer by Haikarainen, Teemu, Krauss, Stefan, Lehtio, Lari

“…Several cellular signaling pathways are regulated by ADP-ribosylation, a posttranslational modification catalyzed by members of the ARTD superfamily…”
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Tankyrases as drug targets by Lehtiö, Lari, Chi, Nai‐Wen, Krauss, Stefan

“…Tankyrase 1 and tankyrase 2 are poly(ADP‐ribosyl)ases that are distinguishable from other members of the enzyme family by the structural features of the…”
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How general is the natural frequency effect? The case of joint probabilities by Stegmüller, Nathalie, Binder, Karin, Krauss, Stefan

“…Natural frequencies are known to improve performance in Bayesian reasoning. However, their impact in situations with two binary events has not yet been…”
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Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma by Dembinski, Jennifer L, Krauss, Stefan

“…Evidence suggests that multiple tumors, including pancreatic adenocarcinoma, display heterogeneity in parameters that are critical for tumor formation,…”
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The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates by Olsen, Petter Angell, Krauss, Stefan

“…HEK293 cells are one of the most widely used cell lines in research, and HEK293 cells are frequently used as an in vitro model for studying the WNT signaling…”
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Meis2 is essential for cranial and cardiac neural crest development by Machon, Ondrej, Masek, Jan, Machonova, Olga, Krauss, Stefan, Kozmik, Zbynek

“…TALE-class homeodomain transcription factors Meis and Pbx play important roles in formation of the embryonic brain, eye, heart, cartilage or hematopoiesis…”
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Pump-less, recirculating organ-on-a-chip (rOoC) platform by Busek, Mathias, Aizenshtadt, Aleksandra, Koch, Timo, Frank, Anna, Delon, Ludivine, Martinez, Mikel Amirola, Golovin, Alexey, Dumas, Clotilde, Stokowiec, Justyna, Gruenzner, Stefan, Melum, Espen, Krauss, Stefan

“…We developed a novel, pump-less directional flow recirculating organ-on-a-chip (rOoC) platform that creates controlled unidirectional gravity-driven flow by a…”
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Teachers' mathematical knowledge, cognitive activation in the classroom, and student progress by Baumert, Jürgen, Kunter, Mareike, Blum, Werner, Brunner, Martin, Voss, Thamar, Jordan, Alexander, Klusmann, Uta, Krauss, Stefan, Neubrand, Michael, Tsai, Yi-Miau

“…In both the United States and Europe, concerns have been raised about whether preservice and in-service training succeeds in equipping teachers with the…”
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Why Can Only 24% Solve Bayesian Reasoning Problems in Natural Frequencies: Frequency Phobia in Spite of Probability Blindness by Weber, Patrick, Binder, Karin, Krauss, Stefan

“…For more than 20 years, research has proven the beneficial effect of natural frequencies when it comes to solving Bayesian reasoning tasks (Gigerenzer and…”
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A New Visualization for Probabilistic Situations Containing Two Binary Events: The Frequency Net by Binder, Karin, Krauss, Stefan, Wiesner, Patrick

“…In teaching statistics in secondary schools and at university, two visualizations are primarily used when situations with two dichotomous characteristics are…”
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An FDA-Validated, Self-Cleaning Liquid Chromatography–Mass Spectrometry System for Determining Small-Molecule Drugs and Metabolites in Organoid/Organ-on-Chip Medium by Kogler, Stian, Pedersen, Gustav Mathingsdal, Martínez-Ramírez, Felipe, Aizenshtadt, Aleksandra, Busek, Mathias, Krauss, Stefan J. K., Wilson, Steven Ray, Røberg-Larsen, Hanne

“…As organoids and organ-on-chip (OoC) systems move toward preclinical and clinical applications, there is an increased need for method validation. Using a…”
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A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice by WAALER, Jo, MACHON, Ondrej, GRADL, Dietmar, VORONKOV, Andrey, VON FRIES, Jens Peter, KRAUSS, Stefan, TUMOVA, Lucie, DINH, Huyen, KORINEK, Vladimir, RAY WILSON, Steven, ERIK PAULSEN, Jan, PEDERSEN, Nina Marie, EIDE, Tor J, MACHONOVA, Olga

“…Increased nuclear accumulation of β-catenin, a mediator of canonical Wnt signaling, is found in numerous tumors and is frequently associated with tumor…”
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Visualizing the Bayesian 2-test case: The effect of tree diagrams on medical decision making by Binder, Karin, Krauss, Stefan, Bruckmaier, Georg, Marienhagen, Jörg

“…In medicine, diagnoses based on medical test results are probabilistic by nature. Unfortunately, cognitive illusions regarding the statistical meaning of test…”
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Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids by Olsen, Christine, Wang, Chencheng, Aizenshtadt, Aleksandra, Abadpour, Shadab, Lundanes, Elsa, Skottvoll, Frøydis Sved, Golovin, Alexey, Busek, Mathias, Krauss, Stefan, Scholz, Hanne, Wilson, Steven Ray

“…For studying stem cell-derived islet organoids (SC-islets) in an organ-on-chip (OoC) platform, we have developed a reversed-phase liquid chromatography-tandem…”
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A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation―Driven Colorectal Tumor Growth by LAU, Ted, CHAN, Emily, MACHON, Ondrej, KORINEK, Vladimir, CHOO, Edna, DIAZ, Dolores, MERCHANT, Mark, POLAKIS, Paul, HOLSWORTH, Daniel D, KRAUSS, Stefan, COSTA, Mike, CALLOW, Marinella, WAALER, Jo, BOGGS, Jason, BLAKE, Robert A, MAGNUSON, Steven, SAMBRONE, Amy, SCHUTTEN, Melissa, FIRESTEIN, Ron

“…Most colorectal cancers (CRC) are initiated by mutations of APC, leading to increased β-catenin-mediated signaling. However, continued requirement of…”
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Global Meta-Analysis of Organoid and Organ-on-Chip Research by Shoji, Jun-ya, Davis, Richard P, Mummery, Christine L, Krauss, Stefan Johannes Karl

“…Abstract Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical, physiological, or pathological states of tissues and organs. These…”
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Academic User View: Organ-on-a-Chip Technology by Busek, Mathias, Aizenshtadt, Aleksandra, Amirola-Martinez, Mikel, Delon, Ludivine, Krauss, Stefan

“…Organ-on-a-Chip (OoC) systems bring together cell biology, engineering, and material science for creating systems that recapitulate the in vivo…”
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Mass spectrometry reveals that oxysterols are secreted from non-alcoholic fatty liver disease induced organoids by Kømurcu, Kristina Sæterdal, Wilhelmsen, Ingrid, Thorne, James L., Krauss, Stefan, Wilson, Steven Ray, Aizenshtadt, Aleksandra, Røberg-Larsen, Hanne

“…Oxysterols are potential biomarkers for liver metabolism that are altered under disease conditions such as non-alcoholic fatty liver disease (NAFLD). We here…”
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Organoids, organ-on-a-chip, separation science and mass spectrometry: An update by Kogler, Stian, Kømurcu, Kristina Sæterdal, Olsen, Christine, Shoji, Jun-ya, Skottvoll, Frøydis Sved, Krauss, Stefan, Wilson, Steven Ray, Røberg-Larsen, Hanne

“…Organoids are 3D models of organs, grown in the laboratory from stem cells. An organ model grown/placed in microfluidic devices is commonly termed an…”
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