Search Results - "Krauss, H A"

Prostamides (prostaglandin‐ethanolamides) and their pharmacology by Woodward, D F, Liang, Y, Krauss, A H‐P

“…The prostamides are part of a large and continually expanding series of pharmacologically unique neutral lipids. They are COX‐2 derived oxidation products of…”
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Pharmacological characterization of a novel antiglaucoma agent, Bimatoprost (AGN 192024) by Woodward, D F, Krauss, A H-P, Chen, J, Liang, Y, Li, C, Protzman, C E, Bogardus, A, Chen, R, Kedzie, K M, Krauss, H A, Gil, D W, Kharlamb, A, Wheeler, L A, Babusis, D, Welty, D, Tang-Liu, D D-S, Cherukury, M, Andrews, S W, Burk, R M, Garst, M E

“…Replacement of the carboxylic acid group of prostaglandin (PG) F(2alpha) with a nonacidic moiety, such as hydroxyl, methoxy, or amido, results in compounds…”
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Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes by Liang, Y, Woodward, D F, Guzman, V M, Li, C, Scott, D F, Wang, J W, Wheeler, L A, Garst, M E, Landsverk, K, Sachs, G, Krauss, A H‐P, Cornell, C, Martos, J, Pettit, S, Fliri, H

“…Background and purpose: A prostamide analogue, bimatoprost, has been shown to be effective in reducing intraocular pressure, but its precise mechanism of…”
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Identification of an antagonist that selectively blocks the activity of prostamides (prostaglandin‐ethanolamides) in the feline iris by Woodward, D F, Krauss, A H, Wang, J W, Protzman, C E, Nieves, A L, Liang, Y, Donde, Y, Burk, R M, Landsverk, K, Struble, C

“…Background and Purpose: The prostamides (prostaglandin‐ethanolamides) and prostaglandin (PG) glyceryl esters are biosynthesized by COX‐2 from the respective…”
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Comparison of leukotriene B4 and D4 effects on human eosinophil and neutrophil motility in vitro by Spada, C S, Nieves, A L, Krauss, A H, Woodward, D F

“…The motility of isolated normal human peripheral blood eosinophils and neutrophils in response to exogenous leukotrienes B4 and D4 was examined by means of a…”
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Replacement of the carboxylic acid group of prostaglandin F2α with a hydroxyl or methoxy substituent provides biologically unique compounds by Woodward, D F, Krauss, A H‐P, Chen, J, Gil, D W, Kedzie, K M, Protzman, C E, Shi, L, Chen, R, Krauss, H A, Bogardus, A, Dinh, H T T, Wheeler, L A, Andrews, S W, Burk, R M, Gac, T, Roof, M B, Garst, M E, Kaplan, L J, Sachs, G, Pierce, K L, Regan, J W, Ross, R A, Chan, M F

“…Replacement of the carboxylic acid group of PGF2α with the non‐acidic substituents hydroxyl (‐OH) or methoxy (‐OCH3) resulted in an unexpected activity…”
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Muscarinic receptor subtypes in human iris-ciliary body measured by immunoprecipitation by Gil, DW, Krauss, HA, Bogardus, AM, WoldeMussie, E

“…To determine the relative levels of the five muscarinic receptor subtypes in the anterior segment of the human eye. Antisera selective for each of the five…”
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Replacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compounds by Woodward, D F, Krauss, A H, Chen, J, Gil, D W, Kedzie, K M, Protzman, C E, Shi, L, Chen, R, Krauss, H A, Bogardus, A, Dinh, H T, Wheeler, L A, Andrews, S W, Burk, R M, Gac, T, Roof, M B, Garst, M E, Kaplan, L J, Sachs, G, Pierce, K L, Regan, J W, Ross, R A, Chan, M F

“…Replacement of the carboxylic acid group of PGF(2alpha) with the non-acidic substituents hydroxyl (-OH) or methoxy (-OCH(3)) resulted in an unexpected activity…”
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A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs by Impagnatiello, F., Borghi, V., Gale, D.C., Batugo, M., Guzzetta, M., Brambilla, S., Carreiro, S.T., Chong, W.K.M., Prasanna, G., Chiroli, V., Ongini, E., Krauss, A.H.P.

“…The IOP lowering effects of NCX 139, a new chemical entity comprising latanoprost amide and a NO-donating moiety, were compared to those of the respective…”
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Determination of leukotriene effects on human neutrophil chemotaxis in vitro by differential assessment of cell motility and polarity by Krauss, A H, Nieves, A L, Spada, C S, Woodward, D F

“…The effects of leukotriene (LT) B4 and D4 on the motility of human peripheral blood neutrophils were investigated employing a novel analytical method. Using…”
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Evidence for human thromboxane receptor heterogeneity using a novel series of 9,11‐cyclic carbonate derivatives of prostaglandin F2α by Krauss, Achim H.‐P., Woodward, David F., Gibson, Linda L., Protzman, Charles E., Williams, Linda S., Burk, Robert M., Gac, Todd S., Roof, Michael B., Abbas, Farhat, Marshall, Kay, Senior, Judith

“…1 The pharmacological activity of a novel series of 9,11‐cyclic carbonate derivatives of prostaglandin F2α (PGF2α) was investigated in various isolated smooth…”
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Replacement of the carboxylic acid group of prostaglandin F 2α with a hydroxyl or methoxy substituent provides biologically unique compounds by Woodward, D F, Krauss, A H‐P, Chen, J, Gil, D W, Kedzie, K M, Protzman, C E, Shi, L, Chen, R, Krauss, H A, Bogardus, A, Dinh, H T T, Wheeler, L A, Andrews, S W, Burk, R M, Gac, T, Roof, M B, Garst, M E, Kaplan, L J, Sachs, G, Pierce, K L, Regan, J W, Ross, R A, Chan, M F

“…Replacement of the carboxylic acid group of PGF 2α with the non‐acidic substituents hydroxyl (‐OH) or methoxy (‐OCH 3 ) resulted in an unexpected activity…”
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Bimatoprost: a novel antiglaucoma agent by Woodward, David F, Phelps, R L, Krauss, A H-P, Weber, A, Short, B, Chen, J, Liang, Y, Wheeler, L A

“…The aim of glaucoma therapy is to preserve vision by reducing intraocular pressure (IOP). Following recent National Eye Institute sponsored studies, it is…”
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Polymorphonuclear leukocyte infiltration into the subretinal choroid and optic nerve in response to leukotrienes by Krauss, AH, Woodward, DF

“…To describe the pattern of leukocyte infiltration in ocular anterior and posterior segment tissues in response to local administration of LTB4 and LTD4…”
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Prostaglandin Effects on the Contractility of Bovine Trabecular Meshwork and Ciliary Muscle by KRAUSS, ACHIM H.-P., WIEDERHOLT, MICHAEL, STURM, ANNETTE, WOODWARD, DAVID F.

“…The ocular hypotensive activity of prostaglandins (PGs) has previously been demonstrated in various species including man. The underlying mechanism of action…”
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Social factors associated with tuberculous meningitis : a study of children and their families in the western cape by KRAUSS-MARS, A. H, LACHMAN, P. I

“…A descriptive study was conducted in order to assess some of the social factors associated with the long-term effects of tuberculous meningitis on children and…”
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A single amino-acid substitution in the EP2 prostaglandin receptor confers responsiveness to prostacyclin analogs by Kedzie, K M, Donello, J E, Krauss, H A, Regan, J W, Gil, D W

“…A high degree of homology between the four Gs-coupled prostaglandin (PG) receptors [EP2, EP4, prostacyclin (IP), PGD2 (DP)] and the four Gq/Gi-coupled…”
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Replacement of the carboxylic acid group of prostaglandin F2[alpha] with a hydroxyl or methoxy substituent provides biologically unique compounds by Woodward, D F, Krauss, A H-P, Chen, J, Gil, D W, Kedzie, K M, Protzman, C E, Shi, L, Chen, R, Krauss, H A, Bogardus, A, Dinh, H T T, Wheeler, L A, Andrews, S W, Burk, R M, Gac, T, Roof, M B, Garst, M E, Kaplan, L J, Sachs, G, Pierce, K L, Regan, J W, Ross, R A, Chan, M F

“…Replacement of the carboxylic acid group of PGF(2alpha) with the non-acidic substituents hydroxyl (-OH) or methoxy (-OCH(3)) resulted in an unexpected activity…”
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Breaking bad news to parents with disabled children--a cross-cultural study by Krauss-Mars, A H, Lachman, P

“…This cross-cultural retrospective study investigates the problems parents experience when told that their child is physically and/or mentally disabled. The…”
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Radioligand binding analysis of receptor subtypes in two FP receptor preparations that exhibit different functional rank orders of potency in response to prostaglandins by Woodward, D F, Fairbairn, C E, Krauss, A H, Lawrence, R A, Protzman, C E

“…The rat colon and Swiss 3T3 cells have been proposed as FP receptor preparations. However, the rank orders of potency for contraction of the rat colon and Ca++…”
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