Search Results - "Krause, Emma"
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A large majority of awake hippocampal sharp-wave ripples feature spatial trajectories with momentum
Published in Neuron (Cambridge, Mass.) (16-02-2022)“…During periods of rest, hippocampal place cells feature bursts of activity called sharp-wave ripples (SWRs). Heuristic approaches have revealed that a small…”
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Journal Article -
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Lesion-induced sprouting promotes neurophysiological integration of septal and entorhinal inputs to granule cells in the dentate gyrus of rats
Published in Neurobiology of learning and memory (01-02-2023)“…•Homotypic and heterotypic pathways interact after neural injury in hippocampus.•A heterotypic pathway contributes to the restoration of neurophysiological…”
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Journal Article -
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Scoring PD-L1 Expression in Urothelial Carcinoma: An International Multi-Institutional Study on Comparison of Manual and Artificial Intelligence Measurement Model (AIM-PD-L1) Pathology Assessments
Published in Virchows Archiv : an international journal of pathology (01-04-2024)“…Assessing programmed death ligand 1 (PD-L1) expression on tumor cells (TCs) using Food and Drug Administration-approved, validated immunoassays can guide the…”
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Journal Article -
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The Spatio-Temporal Dynamics of Awake Hippocampal Sharp-Wave Ripples and Their Relation to Planning
Published 01-01-2021“…Planning through mental simulation, or the anticipation of future action-outcome sequences, is a powerful mechanism for improving action selection. Strikingly,…”
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Dissertation -
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Abstract 6616: Development of a high-throughput image processing pipeline for multiplex immunofluorescence whole slide images at scale
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background. Fluorescent imaging technologies now allow for multiplex immunofluorescence (mIF) for up to 100 targets on a single slide. However, the…”
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Journal Article -
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Abstract 905: ML quantification of tumor-Infiltrating lymphocytes distinguishes immune-phenotypes and reveals phenotypic heterogeneity
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Immune phenotypes (IP), defined by the tumor-infiltrating lymphocyte (TIL) distribution within the tumor microenvironment (TME), is prognostic and…”
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Abstract P5-02-09: Quantitative analysis of fiber-level collagen features in H&E whole-slide images predicts neoadjuvant therapy response in patients with HER2+ breast cancer
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Abstract Background: Neoadjuvant treatment (NAT) combining chemotherapy and HER2-targeted agents is frequently administered to HER2-positive (HER2+) breast…”
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Abstract P4-09-08: AI-based quantitation of cancer cell and fibroblast nuclear morphology reflects transcriptomic heterogeneity and predicts survival in breast cancer
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Abstract Background: Morphological features of cancer cell nuclei are routinely used to assess disease severity and prognosis, and cancer nuclear morphology…”
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Journal Article -
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PLUTO: Pathology-Universal Transformer
Published 13-05-2024“…Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images…”
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Journal Article