Search Results - "Kraus, Lori"
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Acute Lymphoid and Gastrointestinal Toxicity Induced by Selective p38α Map Kinase and Map Kinase–Activated Protein Kinase-2 (MK2) Inhibitors in the Dog
Published in Toxicologic pathology (01-06-2010)“…Exposure to moderately selective p38α mitogen-activated protein kinase (MAPK) inhibitors in the Beagle dog results in an acute toxicity consisting of mild…”
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Apheleia‐001: A novel prescreening study designed to enrich and accelerate Alzheimer’s disease clinical trials by efficiently identifying trial‐eligible participants determined to have a high probability of study inclusion, including amyloid positivity
Published in Alzheimer's & dementia (01-12-2023)“…Background The clinical development ecosystem cannot support the current demand for participants needed in Alzheimer’s disease clinical trials which is further…”
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Quantitative whole-body autoradiography in the pharmaceutical industry: Survey results on study design, methods, and regulatory compliance
Published in Journal of pharmacological and toxicological methods (01-09-2001)“…Introduction: Quantitative whole-body autoradiography (QWBA) is a technique used to determine the tissue distribution of radiolabeled compounds in laboratory…”
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4
Quantitative whole-body autoradiography in the pharmaceutical industry
Published in Journal of pharmacological and toxicological methods (01-09-2001)Get full text
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5
Acute Lymphoid and Gastrointestinal Toxicity Induced by Selective p38a Map Kinase and Map Kinase-Activated Protein Kinase-2 (MK2) Inhibitors in the Dog
Published in Toxicologic pathology (01-06-2010)“…Exposure to moderately selective p38a mitogen-activated protein kinase (MAPK) inhibitors in the Beagle dog results in an acute toxicity consisting of mild…”
Get full text
Journal Article -
6
Disposition and pharmacokinetics of L-N6-(1-iminoethyl)lysine-5-tetrazole-amide, a selective iNOS inhibitor, in rats
Published in Journal of pharmaceutical sciences (01-05-2004)“…The metabolism, pharmacokinetics, tissue distribution, and excretion of L-N6-(1-iminoethyl)lysine-5-tetrazole-amide (L-NIL-TA), a selective inducible NO…”
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7
Ethane Sulfonate Metabolite of Alachlor: Assessment of Oncogenic Potential Based on Metabolic and Mechanistic Considerations
Published in Toxicological sciences (01-05-2000)“…Chronic administration of alachlor has been shown to produce neoplastic responses in the nasal turbinate mucosa, glandular stomach mucosa, and thyroid…”
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8
Acute lymphoid and gastrointestinal toxicity induced by selective p38alpha map kinase and map kinase-activated protein kinase-2 (MK2) inhibitors in the dog
Published in Toxicologic pathology (01-06-2010)“…Exposure to moderately selective p38alpha mitogen-activated protein kinase (MAPK) inhibitors in the Beagle dog results in an acute toxicity consisting of mild…”
Get full text
Journal Article