Search Results - "Kraus, G. A."
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Excited-State Photophysics of Hypericin and Its Hexamethoxy Analog: Intramolecular Proton Transfer as a Nonradiative Process in Hypericin
Published in Journal of the American Chemical Society (02-04-1997)“…The excited-state photophysics of the light induced antiviral agent, hypericin, are compared with those of its methylated analog, hexamethoxyhypericin. This…”
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Chemiluminescent Activation of the Antiviral Activity of Hypericin: A Molecular Flashlight
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-1994)“…Hypericin is a naturally occurring photosensitizer that displays potent antiviral activity in the presence of light. The absence of light in many regions of…”
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IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters
Published in Methods in enzymology (2016)“…Cell communications are essential to the organization, development, and maintenance of multicellular organisms. Much of this communication involves changes in…”
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Synthesis of Hydroxy and Methoxy Perylene Quinones, Their Spectroscopic and Computational Characterization, and Their Antiviral Activity
Published in Photochemistry and photobiology (01-07-2005)“…Hydroxy and methoxy perylene quinones are synthesized in an attempt to isolate the essential spectroscopic and biological features of light-induced antiviral…”
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Excited-State Intramolecular H Atom Transfer of Hypericin and Hypocrellin A Investigated by Fluorescence Upconversion
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (07-10-1999)“…The excited-state intramolecular H atom transfer reaction occurring in hypericin and hypocrellin A is investigated by means of the fluorescence upconversion…”
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Hypericin, Hypocrellin, and Model Compounds: Primary Photoprocesses of Light-Induced Antiviral Agents
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (01-05-1997)“…The excited-state photophysics of the light-induced antiviral agents hypericin and hypocrellin are compared with those of the hexa- and tetramethoxy analogues…”
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Photosensitization is required for inactivation of equine infectious anemia virus by hypericin
Published in Photochemistry and photobiology (01-02-1991)“…Hypericin, a photoreactive polycyclic quinone, was found to dramatically reduce infectivity of cell-free stocks of equine infectious anemia virus. However, the…”
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Hypericin, Hypocrellin, and Model Compounds: Steady-State and Time-Resolved Fluorescence Anisotropies
Published in The journal of physical chemistry. B (19-02-1998)“…Steady-state and time-resolved fluorescence anisotropies of hypericin, hypocrellin, and five other analogues have been measured. The steady-state excitation…”
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Is change in electrical potential or pH a hatching signal for Heterodera glycines?
Published in Phytopathology (01-05-2002)“…ABSTRACT This study explored the possibilities that changes in the egg shell/lipid layer electrical potential or pH communicate external hatching conditions to…”
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Ankylosing Spondylitis versus Nonradiographic Axial Spondyloarthritis: Comparison of Tumor Necrosis Factor Inhibitor Effectiveness and Effect of HLA-B27 Status. An Observational Cohort Study from the Nationwide DANBIO Registry
Published in Journal of rheumatology (01-01-2017)“…To compare baseline disease activity and treatment effectiveness in biologic-naive patients with nonradiographic axial spondyloarthritis (nr-axSpA) and…”
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Toward the Molecular Flashlight: Preparation, Properties, and Photophysics of a Hypericin–luciferin Tethered Molecule
Published in Photochemistry and photobiology (01-08-2002)“…The synthesis of a molecule containing hypericin and luciferin moieties joined by a tether is reported. The light-induced (in vitro) antiviral activity as well…”
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Phenanthrenequinone antiretroviral agents
Published in Bioorganic & medicinal chemistry letters (03-01-2000)“…Compounds 3 and 5 are the first phenanthrenequinones to exhibit significant virucidal activity against the retrovirus equine infectious anemia virus. They…”
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Antiretroviral activity of synthetic hypericin and related analogs
Published in Biochemical and biophysical research communications (15-10-1990)“…Hypericin and pseudohypericin are naturally occurring polycyclic quinones which have recently been shown to inhibit the infectivity of several retroviruses,…”
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Identification of a Vibrational Frequency Corresponding to H-atom Translocation in Hypericin
Published in Photochemistry and photobiology (01-08-2001)“…Using time-resolved infrared spectroscopy, ab initio quantum mechanical calculations and synthetic organic chemistry a region in the infrared spectrum of…”
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An angularly fused three-ring precursor to phytuberin
Published in Acta crystallographica. Section C, Crystal structure communications (01-03-2000)“…The title compound, 3,3a,5,5a,6,7,8,9‐octahydro‐3a‐hydroxy‐5a‐methyl‐8‐(2‐propenyl)furo[3,2‐c]isobenzofuran‐2‐one, C14H20O4, crystallizes with two…”
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Deprotonation of Benzylic Ethers Using a Hindered Phosphazene Base. A Synthesis of Benzofurans from Ortho-Substituted Benzaldehydes
Published in Organic letters (10-08-2000)“…The hindered nonionic phosphazene base P4-t-Bu efficiently deprotonates o-arylmethoxy benzaldehydes, leading to a direct synthesis of benzofurans. Strong ionic…”
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Evaluation of Corn Furan Fatty Acid Putative Endocrine Disruptors on Reproductive Performance in Adult Female Chickens
Published in Poultry science (01-10-2006)“…Based on evidence from rodent models, it was hypothesized that furan fatty acids found in corn would inhibit reproduction in the laying hen. An isomeric…”
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Tumor Cell Toxicity of Hypericin and Related Analogs
Published in Photochemistry and photobiology (01-08-2001)“…A series of hypericin analogs were found to differ in their cytotoxic activity induced by ambient light levels. These analogs vary in their ability to…”
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Synthesis and endothelin receptor binding activity of synthetic analogues of RES-1149-2
Published in Bioorganic & medicinal chemistry letters (01-05-2000)“…A direct synthesis of analogues 6 and 7 is described. The key transformations are the addition of dibromomethyl lithium to a ketone and the subsequent mild…”
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