Search Results - "Kratz, F."

Albumin, a versatile carrier in oncology by Kratz, F

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A triangular canonical form for a class of 0-flat nonlinear systems by Bououden, S., Boutat, D., Zheng, G., Barbot, J.-P., Kratz, F.

“…This article proposes a triangular canonical form for a class of 0-flat nonlinear systems. Necessary and sufficient geometrical conditions are given in order…”
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INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model by Graeser, R., Esser, N., Unger, H., Fichtner, I., Zhu, A., Unger, C., Kratz, F.

“…Summary The (6-maleimidocaproyl)hydrazone derivative of doxorubicin (INNO-206) is an albumin-binding prodrug of doxorubicin with acid-sensitive properties that…”
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Experimental Analysis of an Internet-Based Bilateral Teleoperation System With Motion and Force Scaling Using a Model Predictive Controller by Slama, T., Trevisani, A., Aubry, D., Oboe, R., Kratz, F.

“…This paper presents an experimental investigation of a bilateral generalized predictive controller for scaled teleoperation systems subject to slave force…”
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Targeted drug delivery by in vivo coupling to endogenous albumin: an albumin-binding prodrug of methotrexate (MTX) is better than MTX in the treatment of murine collagen-induced arthritis by Fiehn, C, Kratz, F, Sass, G, Müller-Ladner, U, Neumann, E

“…To examine the effect of an albumin-binding prodrug of methotrexate (MTX) in the treatment of murine collagen-induced arthritis (CIA). The prodrug AWO54 with…”
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Prodrugs of anthracyclines in cancer chemotherapy by Kratz, F, Warnecke, A, Schmid, B, Chung, D-E, Gitzel, M

“…Designing and developing truly tumor-specific prodrugs remains a challenge in the field of cancer chemotherapy. Active targeting strategies, on the one hand,…”
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Acute and repeat-dose toxicity studies of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin (DOXO-EMCH), an albumin-binding prodrug of the anticancer agent doxorubicin by Kratz, F, Ehling, G, Kauffmann, H M, Unger, C

“…The (6-maleimidocaproyl)hydrazone derivative of doxorubicin (DOXO-EMCH) is an albumin-binding prodrug of doxorubicin with acid-sensitive properties that…”
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Advantages and Challenges of Using Physics Curricula as a Model for Reforming an Undergraduate Biology Course by Donovan, D. A, Atkins, L. J, Salter, I. Y, Gallagher, D. J, Kratz, R. F, Rousseau, J. V, Nelson, G. D

“…We report on the development of a life sciences curriculum, targeted to undergraduate students, which was modeled after a commercially available physics…”
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Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging by Di Stefano, G, Fiume, L, Baglioni, M, Bolondi, L, Chieco, P, Kratz, F, Pariali, M, Rubini, G

“…Abstract Background/aims Doxorubicin was conjugated with lactosaminated human albumin, a hepatotropic drug carrier, in order to increase its efficacy in the…”
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Failure detection and reconstruction in switched nonlinear systems by Chaib, S., Boutat, D., Benali, A., Kratz, F.

“…This work presents a novel algorithm for the invertibility of switched nonlinear systems. An invertible switched system is one for which it is possible to…”
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Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites by Iketani, Sho, Hong, Seo Jung, Sheng, Jenny, Bahari, Farideh, Culbertson, Bruce, Atanaki, Fereshteh Fallah, Aditham, Arjun K., Kratz, Alexander F., Luck, Maria I., Tian, Ruxiao, Goff, Stephen P., Montazeri, Hesam, Sabo, Yosef, Ho, David D., Chavez, Alejandro

“…The SARS-CoV-2 3CL protease (3CLpro) is an attractive therapeutic target, as it is essential to the virus and highly conserved among coronaviruses. However,…”
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An Optimal Control Approach for Hybrid Systems by Riedinger, P., lung, C., Kratz, F.

“…In this paper optimal control for hybrid systems will be discussed. While defining hybrid systems as causal and consistent dynamical systems, a general…”
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The binding properties of two antitumor ruthenium(III) complexes to apotransferrin by KRATZ, F, HARTMANN, M, KEPPLER, B, MESSORI, L

“…The interaction of two ruthenium(III) complexes exhibiting high anticancer activity, namely trans-indazolium(bisindazole)tetrachlororuthenate(III) (ru-ind) and…”
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Novel Peptide Conjugates for Tumor-Specific Chemotherapy by Langer, Michael, Kratz, Felix, Rothen-Rutishauser, Barbara, Wunderli-Allenspach, Heidi, Beck-Sickinger, Annette G

“…One of the major problems in cancer chemotherapy are the severe side effects that limit the dose of the anticancer drugs because of their unselectivity for…”
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In vivo evaluation of a novel albumin-binding prodrug of doxorubicin in an orthotopic mouse model of prostate cancer (LNCaP) by Elsadek, B, Graeser, R, Esser, N, Schäfer-Obodozie, C, Tsurumi, C, Abu Ajaj, K, Warnecke, A, Unger, C, Saleem, T, Kratz, F

“…PSA, which is overexpressed in prostate carcinoma, represents a molecular target for selectively releasing an anticancer agent from a prodrug formulation. In…”
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Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier by Di Stefano, G, Kratz, F, Lanza, M, Fiume, L

“…Background. The hepatocyte receptor for asialoglycoproteins, which binds and internalises galactosyl terminating peptides, was found to be expressed also on…”
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Combined Electrical Faults Detection and Diagnosis Using Current Signature Analysis by Babaa, F., Bennis, O., Kratz, F., Hadri-Hamida, A.

“…"Safety, disponibility, and continuity of industrial systems are major concern topics in maintenance". A key entity in the production chain is the asynchronous…”
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Binding of the doxorubicin–lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties by Baglioni, M, Fiume, L, Bolondi, L, Farina, C, Kratz, F, Di Stefano, G

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High-throughput tagging of endogenous loci for rapid characterization of protein function by Kim, Joonwon, Kratz, Alexander F, Chen, Shiye, Sheng, Jenny, Kim, Hark Kyun, Zhang, Liudeng, Singh, Brijesh Kumar, Chavez, Alejandro

“…To facilitate the interrogation of protein function at scale, we have developed high-throughput insertion of tags across the genome (HITAG). HITAG enables…”
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Efficacy and Effectiveness of the ProSomnus® [IA] Sleep Device for the Treatment of Obstructive Sleep Apnea: EFFECTS Study by Stern, Jordan, Lee, Kiwon, Kuhns, Dave, Martinez-Kratz, Jesse F

“…Objectives To evaluate the effectiveness of a new mandibular advancement device (MAD) (Prosomnus® [IA] Sleep Device, Prosomnus Sleep Technologies, Pleasanton…”
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