Search Results - "Kratter, Ian H."
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Targeting H3K4 trimethylation in Huntington disease
Published in Proceedings of the National Academy of Sciences - PNAS (06-08-2013)“…Transcriptional dysregulation is an early feature of Huntington disease (HD). We observed gene-specific changes in histone H3 lysine 4 trimethylation (H3K4me3)…”
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Pilot study of stanford neuromodulation therapy (SNT) for bipolar depression
Published in Brain stimulation (01-03-2024)Get full text
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Network effects of Stanford Neuromodulation Therapy (SNT) in treatment-resistant major depressive disorder: a randomized, controlled trial
Published in Translational psychiatry (03-07-2023)“…Here, we investigated the brain functional connectivity (FC) changes following a novel accelerated theta burst stimulation protocol known as Stanford…”
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Serine 421 regulates mutant huntingtin toxicity and clearance in mice
Published in The Journal of clinical investigation (01-09-2016)“…Huntington's disease (HD) is a progressive, adult-onset neurodegenerative disease caused by a polyglutamine (polyQ) expansion in the N-terminal region of the…”
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Depression history modulates effects of subthalamic nucleus topography on neuropsychological outcomes of deep brain stimulation for Parkinson’s disease
Published in Translational psychiatry (27-05-2022)“…Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain…”
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Sequence-Level Analysis of the Major European Huntington Disease Haplotype
Published in American journal of human genetics (03-09-2015)“…Huntington disease (HD) reflects the dominant consequences of a CAG-repeat expansion in HTT. Analysis of common SNP-based haplotypes has revealed that most…”
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Early differences in lassitude predicts outcomes in Stanford Neuromodulation Therapy for difficult to treat depression
Published in Npj mental health research (28-10-2024)“…Stanford Neuromodulation Therapy (SNT), has recently shown rapid efficacy in difficult to treat (DTT) depression. We conducted an exploratory analysis of…”
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Increased anti-correlation between the left dorsolateral prefrontal cortex and the default mode network following Stanford Neuromodulation Therapy (SNT): analysis of a double-blinded, randomized, sham-controlled trial
Published in Npj mental health research (06-07-2024)“…SNT is a high-dose accelerated intermittent theta-burst stimulation (iTBS) protocol coupled with functional-connectivity-guided targeting that is an…”
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Targeted neurostimulation reverses a spatiotemporal biomarker of treatment-resistant depression
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2023)“…Major depressive disorder (MDD) is widely hypothesized to result from disordered communication across brain-wide networks. Yet, prior resting-state-functional…”
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Sustained Efficacy of Stanford Neuromodulation Therapy (SNT) in Open-Label Repeated Treatment
Published in The American journal of psychiatry (01-01-2024)“…Geoly previously reported that a novel, accelerated TMS paradigm known as Stanford Neuromodulation Therapy (SNT) is safe and highly effective in…”
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Can (or Should) We Treat Depression and Anxiety in Parkinson's Disease Algorithmically?
Published in The American journal of geriatric psychiatry (01-06-2021)“…Martyna et al discuss whether depression and anxiety can be treted in Parkinson's disease algorithmically. Pontone and Mills have authored a well-written and…”
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Anterior Sensorimotor Subthalamic Nucleus Stimulation Is Associated With Improved Voice Function
Published in Neurosurgery (01-10-2020)“…Abstract Background Despite the impact of Parkinson disease (PD) on speech communication, there is no consensus regarding the effect of lead location on…”
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Lateralized Effect of Thalamic Deep Brain Stimulation Location on Verbal Abstraction
Published in Movement disorders (01-08-2021)“…ABSTRACT Background Regionalized thalamic activity has been implicated in language function, and yet the effect of thalamic deep brain stimulation (DBS) on…”
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Magnesium–ibogaine therapy in veterans with traumatic brain injuries
Published in Nature medicine (01-02-2024)“…Traumatic brain injury (TBI) is a leading cause of disability. Sequelae can include functional impairments and psychiatric syndromes such as post-traumatic…”
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PolyQ Disease: Too Many Qs, Too Much Function?
Published in Neuron (Cambridge, Mass.) (23-09-2010)“…The nature of the gain-of-function toxicity found in polyglutamine (polyQ) diseases has been the subject of considerable debate. In this issue of Neuron,…”
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Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins
Published in Proceedings of the National Academy of Sciences - PNAS (06-08-2024)“…Understanding the normal function of the Huntingtin (HTT) protein is of significance in the design and implementation of therapeutic strategies for…”
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A preliminary randomized controlled trial of repetitive transcranial magnetic stimulation applied to the left dorsolateral prefrontal cortex in treatment seeking participants with cannabis use disorder
Published in Drug and alcohol dependence (01-01-2024)“…Cannabis use disorder (CUD) is a common and consequential disorder. When applied to the dorsolateral prefrontal cortex (DLPFC), repetitive transcranial…”
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Association of Preoperative Visual Hallucinations With Cognitive Decline After Deep Brain Stimulation for Parkinson’s Disease
Published in The journal of neuropsychiatry and clinical neurosciences (01-05-2021)“…Objective: Deep brain stimulation (DBS) is effective for the motor symptoms of Parkinson’s disease (PD). Although most patients benefit with minimal cognitive…”
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273. Comparing the Antisuicidal and Antidepressant Effects of Intravenous Ketamine in Major Depressive Episodes With Suicidal Ideation
Published in Biological psychiatry (1969) (15-05-2024)Get full text
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Anterior Sensorimotor Subthalamic Nucleus Stimulation Is Associated With Improved Voice Function
Published in Neurosurgery (01-12-2021)Get full text
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