Search Results - "Kraskouskaya, Dziyana"

An Excimer-Based, Turn-On Fluorescent Sensor for the Selective Detection of Diphosphorylated Proteins in Aqueous Solution and Polyacrylamide Gels by Kraskouskaya, Dziyana, Bancerz, Matthew, Soor, Harjeet S, Gardiner, Jordan E, Gunning, Patrick T

“…Protein phosphorylation is a ubiquitous post-translational modification, which often acts as a switch to proteins’ activation and is frequently perturbed in…”
Get full text

Selective detection of tyrosine-containing proximally phosphorylated motifs using an antenna-free Tb³⁺ luminescent sensor by Duodu, Eugenia, Kraskouskaya, Dziyana, Campbell, Joshua, Graca-Lima, Gustavo, Gunning, Patrick T

“…We herein report the first application of Tb(3+) for the selective detection of an important subset of the phosphoproteome, namely, proximally…”
Get more information

Progress towards the development of SH2 domain inhibitors by Kraskouskaya, Dziyana, Duodu, Eugenia, Arpin, Carolynn C, Gunning, Patrick T

“…Src homology 2 (SH2) domains are 100 amino acid modular units, which recognize and bind to tyrosyl-phosphorylated peptide sequences on their target proteins,…”
Get more information

Histone deacetylase inhibitors as a potential new treatment for psoriatic disease and other inflammatory conditions by Nazri, Jehan Mohammad, Oikonomopoulou, Katerina, de Araujo, Elvin D., Kraskouskaya, Dziyana, Gunning, Patrick T., Chandran, Vinod

“…Collectively known as psoriatic disease, psoriasis and psoriatic arthritis (PsA) are immune-mediated inflammatory diseases in which patients present with…”
Get full text

Abstract LB-108: A potent and selective small molecule degrader of STAT5 for the treatment of hematological malignancies by Park, Ji Sung, Tin, Gary, de Araujo, Elvin D., Orlova, Anna, Sorger, Helena, Grebien, Florian, Heyes, Elizabeth, Geletu, Mulu, Villalonga, Ruth, Sampedro, Angel, Sedighi, Abootaleb, Herling, Marco, Mustjoki, Satu, Eram, Mohammad S., Ahmar, Siawash, Moriggl, Richard, O'Meara, Jeff A., Proudfoot, John, Noel, Kay, Kraskouskaya, Dziyana, Fleck, Roman, Gunning, Patrick T.

“…STAT5 is a member of the signal transducer and activator of transcription family of proteins and is widely recognized as an oncogenic master regulator of…”
Get full text

ProxyPhos sensors for the detection of negatively charged membranes by Murcar-Evans, Bronte I, Cabral, Aaron D, Toutah, Krimo, de Araujo, Elvin D, Lai, Angel, Macdonald, Peter M, Berger-Becvar, Angelika, Kraskouskaya, Dziyana, Gunning, Patrick T

“…Membrane-embedded negatively charged phospholipids (MENCP) can be used as biomarkers for a range of biological processes, including early detection of…”
Get more information

A tool for the selective sequestration of ATP and PPi to aid in-solution phosphopeptide detection assays by Duodu, Eugenia, Kraskouskaya, Dziyana, Gómez-Biagi, Rodolfo F, Gunning, Patrick T

“…The presence of small phospho-anions, such as PPi and ATP in protein samples often complicates the robust detection of phosphoproteins by metal-based…”
Get more information

Sensitive Detection of Broad-Spectrum Bacteria with Small-Molecule Fluorescent Excimer Chemosensors by Cabral, Aaron D, Rafiei, Nafiseh, de Araujo, Elvin D, Radu, Tudor B, Toutah, Krimo, Nino, Daniel, Murcar-Evans, Bronte I, Milstein, Joshua N, Kraskouskaya, Dziyana, Gunning, Patrick T

“…Antibiotic resistance is a major problem for world health, triggered by the unnecessary usage of broad-spectrum antibiotics on purportedly infected patients…”
Get full text

Design and Development of Fluorescent Sensors for the Detection of Proximally Phosphorylated Peptide and Protein Motifs by Kraskouskaya, Dziyana

“…While protein phosphorylation is recognized as a chief regulator of protein activity, little is known about the significance of the relative spatial separation…”
Get full text