Time–Frequency Analysis of The Second Heart Sound to Assess Pulmonary Artery Pressure

Time–Frequency Analysis of The Second Heart Sound to Assess Pulmonary Artery Pressure

A method is proposed for noninvasive assessment of the pulmonary artery pressure based on separation of the aortic and pulmonary components of the second heart sound S 2 and determining the delay time between them. The algorithm for separating the aortic and pulmonary components is based on the Wign...

Full description

Saved in:
Bibliographic Details
Published in:Acoustical physics Vol. 66; no. 5; pp. 542 - 547
Main Authors: Andreev, V. G., Gramovich, V. V., Krasikova, M. V., Korolkov, A. I., Vyborov, O. N., Danilov, N. M., Martynyuk, T. V., Rodnenkov, O. V., Rudenko, O. V.
Format: Journal Article
Language:English
Published: Moscow Pleiades Publishing 01-09-2020
Springer Nature B.V
Subjects:
Acoustics
Acoustics of Living Systems. Biomedical Acoustics
Algorithms
Aorta
Cardiology
Catheterization
Correlation analysis
Delay time
Hypertension
Physics
Physics and Astronomy
Pulmonary arteries
Research facilities
Second heart sound
Time lag
Time measurement
Time-frequency analysis
Veins & arteries
Wigner–Ville transform
PH
catheterization of the right heart
aortic and pulmonary components
second heart sound
auscultation
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A method is proposed for noninvasive assessment of the pulmonary artery pressure based on separation of the aortic and pulmonary components of the second heart sound S 2 and determining the delay time between them. The algorithm for separating the aortic and pulmonary components is based on the Wigner–Ville transform. Analysis of the phonocardiograms of 96 patients with pulmonary hypertension (PH) recorded by doctors of the Scientific Research Center of Cardiology using an original set of equipment was carried out. In 53 patients with PH, it was possible to separate S 2 signals into components and determine the delays between them. We construct the dependence of delays between the components on pulmonary artery pressure (PAP), measured by right heart catheterization (RHC). For seven patients with PH, the obtained dependences were used to predict the PAP value from the measured time delay. For five patients, the determination coefficient for the predicted PAP values was 0.83, which indicates a fairly good correlation with measurements by the RHC method.
ISSN:1063-7710
1562-6865
DOI:10.1134/S1063771020050012