Search Results - "Krantz, SB"

Progress in understanding the pathogenesis of the anemia of chronic disease by MEANS, R. T, KRANTZ, S. B

“…Improved understanding of the inflammatory response and the identification and characterization of the specific cytokines involved, as well as improved…”
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Identification of an Acquired JAK2 Mutation in Polycythemia Vera by Zhao, Runxiang, Xing, Shu, Li, Zhe, Fu, Xueqi, Li, Qingshan, Krantz, Sanford B, Zhao, Zhizhuang Joe

“…Polycythemia vera (PV) is a human clonal hematological disorder. The molecular etiology of the disease has not been identified. PV hematopoietic progenitor…”
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Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells by WICKREMA, A, KRANTZ, S. B, WINKELMANN, J. C, BONDURANT, M. C

“…Partially purified human burst-forming unit-erythroid (BFU-E) cells from peripheral blood were cultured for 6 to 8 days to obtain colony-forming unit-erythroid…”
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Interferon γ Induces Upregulation and Activation of Caspases 1, 3, and 8 to Produce Apoptosis in Human Erythroid Progenitor Cells by Dai, Chunhua, Krantz, Sanford B.

“…Interferon γ (IFNγ) induces apoptosis in purified human erythroid colony-forming cells (ECFC) and inhibits cell growth. Fas (APO-1; CD95) and Fas ligand (FasL)…”
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Erythropoietin by Krantz, Sanford B.

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Receptors for Erythropoietin in Mouse and Human Erythroid Cells and Placenta by Sawyer, Stephen T., Krantz, Sanford B., Sawada, Ken-ichi

“…High and lower affinity receptors for erythropoietin (EP) were initially identified on a very pure population of EP- responsive erythroblasts obtained from the…”
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Anemia of the critically ill: “Acute” anemia of chronic disease by Corwin, Howard L, Krantz, Sanford B

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Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB by Dai, Chunhua, Chung, Ik-Joo, Krantz, Sanford B.

“…The aim of this study was to explore the mechanism by which increased erythropoiesis occurs in polycythemia vera (PV). CD34 + and erythroid colony-forming…”
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Synergistic Activation of MAP Kinase (ERK1/2) by Erythropoietin and Stem Cell Factor Is Essential for Expanded Erythropoiesis by Sui, Xingwei, Krantz, Sanford B., You, Min, Zhao, Zhizhuang

“…Stem cell factor (SCF) and erythropoietin (EPO) work synergistically to support erythropoiesis, but the mechanism for this synergism is unknown. By using…”
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Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon γ to produce erythroid cell apoptosis by DAI, C.-H, PRICE, J. O, BRUNNER, T, KRANTZ, S. B

“…Interferon gamma (IFNgamma) inhibits the growth and differentiation of highly purified human erythroid colony-forming cells (ECFCs) and induces erythroblast…”
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PTP-MEG2 is activated in polycythemia vera erythroid progenitor cells and is required for growth and expansion of erythroid cells by Xu, Ming-jiang, Sui, Xingwei, Zhao, Runxiang, Dai, Chunhua, Krantz, Sanford B., Zhao, Zhizhuang Joe

“…Polycythemia vera (PV) is a human clonal hematologic disorder. Previously we demonstrated that erythroid colony-forming cells (ECFCs) from PV patients…”
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Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells by Muta, K, Krantz, S B, Bondurant, M C, Wickrema, A

“…Erythropoietin (EP), insulin-like growth factor I (IGF-I) and stem cell factor (SCF) each reduce apoptosis of human erythroid progenitor cells. To determine if…”
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Abundance and Stability of Erythropoietin Receptor mRNA in Mouse Erythroid Progenitor Cells by Wickrema, Amittha, Bondurant, Maurice C., Krantz, Sanford B.

“…The abundance and stability of erythropoietin (EPO) receptor mRNA was measured in Friend virus-infected mouse splenic erythroblast (FVA) cells. FVA cells…”
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Stem cell factor increases the expression of FLIP that inhibits IFNγ-induced apoptosis in human erythroid progenitor cells by Chung, Ik-Joo, Dai, Chunhua, Krantz, Sanford B.

“…Interferon γ (IFNγ) acts on human erythroid colony-forming cells (ECFCs) to up-regulate Fas, without a demonstrable change of Fas ligand (FasL) or…”
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Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signalling pathways by Sui, Xingwei, Krantz, Sanford B., Zhao, Zhizhuang Joe

“…Erythropoietin (EPO) and stem cell factor (SCF) are two important factors in human erythropoiesis. We have recently demonstrated that SCF and EPO…”
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Role of Tyrosine Kinases and Phosphatases in Polycythemia Vera by Zhao, Zhizhuang Joe, Vainchenker, William, Krantz, Sanford B., Casadevall, Nicole, Constantinescu, Stefan N.

“…Protein tyrosine kinases (PTKs) and phosphatases (PTPs) play a crucial role in normal cell development, and dysfunction of these enzymes has been implicated in…”
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Specific Interaction of Protein Tyrosine Phosphatase-MEG2 with Phosphatidylserine by Zhao, Runxiang, Fu, Xueqi, Li, Qingshan, Krantz, Sanford B, Zhao, Zhizhuang Joe

“…Protein tyrosine phosphatase (PTP)-MEG2 is an intracellular tyrosine phosphatase that contains a Sec14 homology domain. We have purified the full-length and…”
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Studies on Red Cell Aplasia, I. Demonstration of a Plasma Inhibitor to Heme Synthesis and an Antibody to Erythroblast Nuclei by Krantz, Sanford B., Kao, Vincent

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Interferon γ Downregulates Stem Cell Factor and Erythropoietin Receptors But Not Insulin-Like Growth Factor-I Receptors in Human Erythroid Colony-Forming Cells by Taniguchi, Shuichi, Dai, Chun-Hua, Price, James O., Krantz, Sanford B.

“…Interferon γ (IFNγ) has been shown to inhibit proliferation and differentiation of erythroid progenitor cells and to produce apoptosis of erythroid cells,…”
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Apoptosis of human erythroid colony-forming cells is decreased by stem cell factor and insulin-like growth factor I as well as erythropoietin by Muta, K, Krantz, S B

“…To clarify the manner by which erythropoietin (EP), stem cell factor (SCF), or insulin-like growth factor I (IGF-I) regulate erythropoiesis, apoptosis of human…”
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