Search Results - "Krampfl, K"

Prevalence and prognostic impact of comorbidities in amyotrophic lateral sclerosis by Körner, S., Kollewe, K., Ilsemann, J., Müller-Heine, A., Dengler, R., Krampfl, K., Petri, S.

“…Background and purpose Amyotrophic lateral sclerosis (ALS) is characterized by rapidly progressive paralysis of striated muscles due to the loss of upper and…”
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AMPA-type glutamate receptors and excitotoxicity: Molecular neurophysiology and pharmacology by Krampfl, K

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A long-term follow-up of botulinum toxin A in cervical dystonia by Mohammadi, B., Buhr, N., Bigalke, H., Krampfl, K., Dengler, R., Kollewe, K.

“…Objective: Cervical dystonia (CD) is the most common form of adult-onset focal dystonia, and botulinum toxin A (BoNT-A) has become the first-line treatment for…”
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High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study by Graf, M, Ecker, D, Horowski, R, Kramer, B, Riederer, P, Gerlach, M, Hager, C, Ludolph, A C, Becker, G, Osterhage, J, Jost, W H, Schrank, B, Stein, C, Kostopulos, P, Lubik, S, Wekwerth, K, Dengler, R, Troeger, M, Wuerz, A, Hoge, A, Schrader, C, Schimke, N, Krampfl, K, Petri, S, Zierz, S, Eger, K, Neudecker, S, Traufeller, K, Sievert, M, Neundörfer, B, Hecht, M

“…Increasing evidence has suggested that oxidative stress may be involved in the pathogenesis of amyotrophic lateral sclerosis (ALS). The antioxidant vitamin E…”
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Rapsyn N88K is a frequent cause of congenital myasthenic syndromes in European patients by Müller, J S, Mildner, G, Müller-Felber, W, Schara, U, Krampfl, K, Petersen, B, Petrova, S, Stucka, R, Mortier, W, Bufler, J, Kurlemann, G, Huebner, A, Merlini, L, Lochmüller, H, Abicht, A

“…Mutations in various genes of the neuromuscular junction may cause congenital myasthenic syndromes (CMS). Most mutations identified to date affect the…”
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Anterior cysts of the spine by Schmalbach, S, Petri, S, GOetz, F, Dengler, R, Krampfl, K

“…We describe three patients referred to our ALS/MND clinic with suspected diagnosis of amyotrophic lateral sclerosis (ALS). The patients were all male, middle…”
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Molecular mechanisms of interaction between the neuroprotective substance riluzole and GABA(A)-receptors by Jahn, K, Schlesinger, F, Jin, L J, Dengler, R, Bufler, J, Krampfl, K

“…The antiepileptic drug riluzole is used as a therapeutic agent in amyotrophic lateral sclerosis due to its neuroprotective effects. Besides presynaptic…”
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Molecular mechanisms of interaction between the neuroprotective substance riluzole and GABAA-receptors by Jahn, K., Schlesinger, F., Jin, L. J., Dengler, R., Bufler, J., Krampfl, K.

“…The antiepileptic drug riluzole is used as a therapeutic agent in amyotrophic lateral sclerosis due to its neuroprotective effects. Besides presynaptic…”
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Modulation of Synaptic Transmission and Analysis of Neuroprotective Effects of Valproic Acid and Derivates in Rat Embryonic Motoneurons by Ragancokova, D, Song, Y, Nau, H, Dengler, R, Krampfl, K, Petri, S

“…Amyotrophic lateral sclerosis is a devastating motoneuron disorder for which no effective treatment exists. There is some evidence for neuroprotective effects…”
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Clinical and experimental neurophysiology in amyotrophic lateral sclerosis (ALS) by Dengler, R, Petri, S, Krampfl, K

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Anterior cysts of the spine: A difficult differential diagnosis to amyotrophic lateral sclerosis by Schmalbach, S., Petri, S., Götz, F., Dengler, R., Krampfl, K.

“…We describe three patients referred to our ALS/MND clinic with suspected diagnosis of amyotrophic lateral sclerosis (ALS). The patients were all male, middle…”
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Analysis of Neuroprotective Effects of Valproic Acid on Primary Motor Neurons in Monoculture or Co-cultures with Astrocytes or Schwann Cells by Ragancokova, D, Jahn, K, Kotsiari, A, Schlesinger, F, Haastert, K, Stangel, M, Petri, S, Krampfl, K

“…Chronic dysregulation of the intracellular Ca²⁺ homeostasis (excitotoxicity) is thought to contribute to the development of motor neuron diseases. Valproic…”
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The cellular mRNA expression of GABA and glutamate receptors in spinal motor neurons of SOD1 mice by Petri, S., Schmalbach, S., Grosskreutz, J., Krampfl, K., Grothe, C., Dengler, R., Van Den Bosch, L., Robberecht, W., Bufler, J.

“…ALS is a fatal neurodegenerative disorder characterized by a selective loss of upper motor neurons in the motor cortex and lower motor neurons in the brain…”
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Interaction of androsterone and progesterone with inhibitory ligand-gated ion channels: a patch clamp study by Ziegler, Elke, Bodusch, M., Song, Y., Jahn, K., Wolfes, H., Steinlechner, S., Dengler, R., Bufler, J., Krampfl, K.

“…Gamma-aminobutyric acid receptor type A (GABA A ) receptor channels mediate fast inhibitory neurotransmission throughout the central nervous system while the…”
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68. Cortical and subcortical motor activity in patients with sporadic ALS studied with fMRI by Mohammadi, B, Kollewe, K, Krampfl, K, Samii, A, Dengler, R, Münte, T

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1.255 Experience of up to ten years treatment with albumin-diluted botulinum toxin type A by Mohammadi, B, Kollewe, K, Wegener, M, Krampfl, K, Dengler, R

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1.254 Long-term follow-up of cervical dystonia patients treated with Botulinum toxin A by Kollewe, K, Buhr, N, Krampfl, K, Dengler, R, Mohammadi, B

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IgG from patients with Guillain-Barré syndrome interact with nicotinic acetylcholine receptor channels by Krampfl, K., Mohammadi, B., Buchwald, B., Jahn, K., Dengler, R., Toyka, K.V., Bufler, J.

“…In Guillain–Barré syndrome (GBS), immunoglobulin G (IgG) antibodies block neuromuscular transmission pre‐ and postsynaptically and thus are of potential…”
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Ligand-gated channels in early mesencephalic neuronal precursors: immunocytochemical and electrophysiological analysis by Schlesinger, F., Meywirth, J., Krampfl, K., Grosskreutz, J., Petri, S., Mauth, C., Just, L., Bader, A., Bufler, J.

“…Neuronal precursors play an important role in potential regenerative therapeutic strategies in different neurodegenerative diseases, e.g. Parkinson's disease…”
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Functional diversity of recombinant human AMPA type glutamate receptors: possible implications for selective vulnerability of motor neurons by Krampfl, K, Schlesinger, F, Wolfes, H, Dengler, R, Bufler, J

“…Lower motor neurons are known to be susceptible to glutamate-mediated cell damage via overstimulation of AMPA type glutamate receptors (GluR). The molecular…”
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