Search Results - "Kramers, Bart J"
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Determinants of Urine Volume in ADPKD Patients Using the Vasopressin V2 Receptor Antagonist Tolvaptan
Published in American journal of kidney diseases (01-03-2019)“…The vasopressin V2 receptor antagonist (V2RA) tolvaptan is the first drug that has been shown to slow the rate of kidney function decline in patients with…”
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Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors
Published in Journal of clinical medicine (31-05-2019)“…Sodium glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of heart and kidney failure in patients with type 2 diabetes, possibly due to diuretic…”
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Effects of Treating Primary Aldosteronism on Renal Function
Published in The journal of clinical hypertension (Greenwich, Conn.) (01-03-2017)“…Longstanding primary aldosteronism (PA) has deleterious effects on renal function, often masked until treatment (adrenalectomy or spironolactone) is initiated…”
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HYDROchlorothiazide versus placebo to PROTECT polycystic kidney disease patients and improve their quality of life: study protocol and rationale for the HYDRO-PROTECT randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (14-02-2024)“…Autosomal dominant polycystic kidney disease (ADPKD) leads to progressive renal cyst formation and loss of kidney function in most patients. Vasopressin 2…”
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Case report: a thiazide diuretic to treat polyuria induced by tolvaptan
Published in BMC nephrology (03-07-2018)“…Currently, the vasopressin V2 receptor antagonist tolvaptan is the only available treatment for autosomal dominant polycystic kidney disease (ADPKD), but there…”
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Effects of salt and protein intake on polyuria in V2RA-treated ADPKD patients
Published in Nephrology, dialysis, transplantation (27-03-2024)“…ABSTRACT Background The only treatment proven to be renoprotective in autosomal dominant polycystic kidney disease (ADPKD) is a vasopressin V2-receptor…”
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Prostaglandin E2, osmoregulation and disease progression in autosomal dominant polycystic kidney disease
Published in Clinical journal of the American Society of Nephrology (01-11-2023)“…Prostaglandin E2 (PGE2) plays a physiological role in osmoregulation, a process that is affected early in autosomal dominant polycystic kidney disease (ADPKD)…”
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Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD: A Randomized Crossover Trial
Published in Clinical journal of the American Society of Nephrology (01-04-2022)“…The vasopressin V2 receptor antagonist tolvaptan is the only drug that has been proven to be nephroprotective in autosomal dominant polycystic kidney disease…”
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Thiazide diuretics and the rate of disease progression in autosomal dominant polycystic kidney disease: an observational study
Published in Nephrology, dialysis, transplantation (27-09-2021)“…Abstract Background In autosomal dominant polycystic kidney disease (ADPKD), hypertension is prevalent and cardiovascular events are the main cause of death…”
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The association of glucagon with disease severity and progression in patients with autosomal dominant polycystic kidney disease: an observational cohort study
Published in Clinical kidney journal (01-12-2021)“…ABSTRACT Background Mammalian target of rapamycin (mTOR) inhibitors and ketogenesis have been shown to ameliorate disease progression in experimental autosomal…”
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Effect of a Somatostatin Analogue on the Vasopressin Pathway in Patients With ADPKD
Published in Kidney international reports (01-08-2019)Get full text
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SaO003USE OF THIAZIDE DIURETICS DOES NOT WORSEN DISEASE PROGRESSION IN ADPKD
Published in Nephrology, dialysis, transplantation (01-06-2019)Get full text
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