Search Results - "Kramer, Herbert J."

An overview of small satellites in remote sensing by Kramer, Herbert J., Cracknell, Arthur P.

“…This article gives a global overview of some aspects of small satellite developments since the launch of Sputnik-1 50 years ago. These developments are…”
Get full text

Identification of Putative Natriuretic Hormones Isolated from Human Urine by Kramer, Herbert J

“…This brief review describes some representative methodological approaches to the isolation of putative endogenous inhibitors of epithelial sodium transport -…”
Get full text

Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension by Neckář, Jan, Kopkan, Libor, Husková, Zuzana, Kolář, František, Papoušek, František, Kramer, Herbert J, Hwang, Sung Hee, Hammock, Bruce D, Imig, John D, Malý, Jiří, Netuka, Ivan, Ošťádal, Bohuslav, Červenka, Luděk

“…The present study was undertaken to evaluate the effects of chronic treatment with c-AUCB {cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid}, a…”
Get more information

Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats by Sedláková, Lenka, Čertíková Chábová, Věra, Doleželová, Šárka, Škaroupková, Petra, Kopkan, Libor, Husková, Zuzana, Červenková, Lenka, Kikerlová, Soňa, Vaněčková, Ivana, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Kujal, Petr, Kramer, Herbert J., Červenka, Luděk

“…Background: Early addition of endothelin (ET) type A (ET A ) receptor blockade to complex renin-angiotensin system (RAS) blockade has previously been shown to…”
Get full text

Impairment of the angiotensin-converting enzyme 2–angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension by Bürgelová, Marcela, Vaňourková, Zdenka, Thumová, Monika, Dvořák, Pavel, Opočenský, Martin, Kramer, Herbert J, Želízko, Michal, Malý, Jan, Bader, Michael, Červenka, Luděk

“…OBJECTIVERecent studies have shown that the heptapeptide angiotensin-(1-7) [Ang-(1-7)] exerts important vasoactive actions and can act as an endogenous…”
Get full text

Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats by Rakusan, Dan, Kujal, Petr, Kramer, Herbert J, Husková, Zuzana, Vanourková, Zdenka, Vernerová, Zdenka, Mrázová, Iveta, Thumová, Monika, Cervenka, Ludek, Vanecková, Ivana

“…The effects of the human renin inhibitor aliskiren on blood pressure (BP), end-organ damage, proteinuria, and tissue and plasma angiotensin (ANG) II levels in…”
Get more information

In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis by BOKEMEYER, Dirk, PANEK, Darius, KRAMER, Herbert J, LINDEMANN, Marion, KITAHARA, Masashi, BOOR, Peter, KERJASCHKI, Dontscho, TRZASKOS, James M, FLOEGE, Jürgen, OSTENDORF, Tammo

“…Evidence was recently provided for the activation of extracellular signal-regulated kinase (ERK), the best characterized mitogen-activated protein kinase, as…”
Get full text

N-Acetylcysteine Attenuates Iodine Contrast Agent-Induced Nephropathy in 5/6-Nephrectomized Rats by Šochman, Jan, Peregrin, Jan H., Bürgelová, Marcela, Kopkan, Libor, Kramer, Herbert J., Červenka, Luděk

“…Aims: In the present study we tested the efficacy of N-acetylcysteine (NAC) to minimize nephrotoxic effects of iodine contrast agents in intact rats as well as…”
Get full text

Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats by Jíchová, Šárka, Kopkan, Libor, Husková, Zuzana, Doleželová, Šárka, Neckář, Jan, Kujal, Petr, Vernerová, Zdenka, Kramer, Herbert J, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Reddy, Rami N, Falck, John R, Imig, John D, Červenka, Luděk

“…OBJECTIVE:We evaluated the therapeutic effectiveness of a new, orally active epoxyeicosatrienoic acid analog (EET-A) in rats with angiotensin II (ANG…”
Get full text

AT1 receptor antisense therapy transiently lowers blood pressure in Ren-2 transgenic rats by Vaněčková, Ivana, Kopkan, Libor, Husková, Zuzana, Vaňourková, Zdenka, Schejbalová, Stanislava, Červenka, Luděk, Kramer, Herbert J

“…Abstract The effectiveness of antisense (AS) phosphorothioated oligodeoxynucleotides (AS-ODN) targeted to the angiotensin (ANG) type 1 (AT1 ) receptor, was…”
Get full text

Intrarenal alterations of the angiotensin-converting enzyme type 2/angiotensin 1-7 complex of the renin-angiotensin system do not alter the course of malignant hypertension in Cyp1a1-Ren-2 transgenic rats by Husková, Zuzana, Kopkan, Libor, Červenková, Lenka, Doleželová, Šárka, Vaňourková, Zdeňka, Škaroupková, Petra, Nishiyama, Akira, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kramer, Herbert J., Červenka, Luděk

“…Summary The role of the intrarenal renin‐angiotensin system (RAS) in the pathophysiology of malignant hypertension is not fully understood. Accumulating…”
Get full text

Differential activation of mitogen-activated protein kinases in experimental mesangioproliferative glomerulonephritis by BOKEMEYER, D, OSTENDORF, T, KUNTER, U, LINDEMANN, M, KRAMER, H. J, FLOEGE, J

“…Multiple extracellular mitogens are involved in the pathogenesis of proliferative forms of glomerulonephritis (GN). In vitro studies demonstrate the pivotal…”
Get full text

A tribute to Hugh de Wardener by Buckalew, Vardaman M, Gonick, Harvey C, Kramer, Herbert J, Lichardus, Branislav

Get full text

Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats by Kujal, Petr, Čertíková Chábová, Vera, Škaroupková, Petra, Husková, Zuzana, Vernerová, Zdena, Kramer, Herbert J, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kitada, Kento, Nishiyama, Akira, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Červenka, Ludek

“…Summary The aim of the present study was to test the hypothesis that increasing kidney tissue concentrations of epoxyeicosatrienoic acids (EETs) by preventing…”
Get full text

Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats by Sporková, Alexandra, Kopkan, Libor, Varcabová, Sárka, Husková, Zuzana, Hwang, Sung Hee, Hammock, Bruce D, Imig, John D, Kramer, Herbert J, Cervenka, Ludek

“…Alterations in renal function contribute to Goldblatt two-kidney, one-clip (2K1C) hypertension. A previous study indicated that bioavailability of cytochrome…”
Get more information

Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: Studies in Cyp1a1-Ren-2 transgenic rats by Sporková, Alexandra, Jíchová, Šárka, Husková, Zuzana, Kopkan, Libor, Nishiyama, Akira, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kramer, Herbert J, Červenka, Luděk

“…Summary Recent studies have shown that the long‐term antihypertensive action of soluble epoxide hydrolase inhibition (sEH) in angiotensin‐II (AngII)‐dependent…”
Get full text

Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME by Honetschlägerová, Zuzana, Kitada, Kento, Husková, Zuzana, Sporková, Alexandra, Kopkan, Libor, Bürgelová, Marcela, Varcabová, Šárka, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D, Imig, John D, Kramer, Herbert J, Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk

“…OBJECTIVE:The present study was performed to investigate in a model of malignant hypertension if the antihypertensive actions of soluble epoxide hydrolase…”
Get full text

Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system by Varcabova, Sarka, Huskova, Zuzana, Kramer, Herbert J, Hwang, Sung Hee, Hammock, Bruce D, Imig, John D, Kitada, Kento, Cervenka, Ludek

“…Summary The aim of the present study was to evaluate the hypothesis that the antihypertensive effects of inhibition of soluble epoxide hydrolase (sEH) are…”
Get full text

Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats by Alánová, Petra, Husková, Zuzana, Kopkan, Libor, Sporková, Alexandra, Jíchová, Šárka, Neckář, Jan, Imig, John D, Klevstig, Martina, Kolář, František, Rami Reddy, N, Falck, John R, Sadowski, Janusz, Nishiyama, Akira, Kramer, Herbert J, Melenovský, Vojtěch, Červenková, Lenka, Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk

“…Abstract This study examined the effects of a novel orally active 14,15-epoxyeicosatrienoic acid analog (EET-A) on blood pressure (BP) and myocardial infarct…”
Get full text

Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren‐2 transgenic rats with inducible hypertension by Honetschlägerová, Zuzana, Husková, Zuzana, Vaňourková, Zdeňka, Sporková, Alexandra, Kramer, Herbert J., Hwang, Sung Hee, Tsai, Hsing‐Ju, Hammock, Bruce D., Imig, John D., Červenka, Luděk, Kopkan, Libor

“…Non‐technical summary Arachidonic acid metabolites called epoxyeicosatrienoic acids (EETs) influence vascular tone and renal tubular sodium and water transport…”
Get full text