Search Results - "Kramer, Gerald"
-
1
Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates
Published in Biochemical and biophysical research communications (20-10-2018)“…The mammalian paraoxonases (PONs 1, 2 and 3) are a family of esterases that are highly conserved within and between species. They exhibit antioxidant and…”
Get full text
Journal Article -
2
The effect of disease misclassification on the ability to detect a gene-environment interaction: implications of the specificity of case definitions for research on Gulf War illness
Published in BMC medical research methodology (20-11-2023)“…Since 1997, research on Gulf War illness (GWI) has predominantly used 3 case definitions-the original Research definition, the CDC definition, and…”
Get full text
Journal Article -
3
Dominant Role of Paraoxonases in Inactivation of the Pseudomonas aeruginosa Quorum-Sensing Signal N-(3-Oxododecanoyl)-L-Homoserine Lactone
Published in Infection and Immunity (01-06-2008)“…The pathogenic bacterium Pseudomonas aeruginosa causes serious infections in immunocompromised patients. N-(3-Oxododecanoyl)-L-homoserine lactone (3OC12-HSL)…”
Get full text
Journal Article -
4
Novel Paraoxonase 2-Dependent Mechanism Mediating the Biological Effects of the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxo-Dodecanoyl)-L-Homoserine Lactone
Published in Infection and immunity (01-09-2015)“…Pseudomonas aeruginosa produces N-(3-oxo-dodecanoyl)-L-homoserine lactone (3OC12), a crucial signaling molecule that elicits diverse biological responses in…”
Get full text
Journal Article -
5
Methods for measuring serum activity levels of the 192 Q and R isoenzymes of paraoxonase 1 in QR heterozygous individuals
Published in Clinical chemistry (Baltimore, Md.) (01-08-2013)“…Paraoxonase 1 (PON1), an esterase that hydrolyzes toxic organophosphates and has antioxidative and antiatherogenic properties, contains a common polymorphism…”
Get full text
Journal Article -
6
Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin
Published in Biochemical journal (27-01-2010)“…Two virulence factors produced by Pseudomonas aeruginosa are pyocyanin and N-(3-oxododecanoyl)-L-homoserine lactone (3OC12). Pyocyanin damages host cells by…”
Get more information
Journal Article -
7
Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder
Published in Psychiatry research (25-03-2001)“…Plasma gamma-aminobutyric acid (GABA) levels are decreased in some patients with depression, mania and alcoholism. Medications which increase plasma GABA…”
Get full text
Journal Article -
8
The influence of gender and the estrous cycle on learned helplessness in the rat
Published in Biological psychology (01-11-2001)“…Although the etiology of clinical depression is unknown, women are more likely to suffer from major depressive disorder than men. In addition, in some women,…”
Get full text
Journal Article -
9
Depletion of Tissue Angiotensin-Converting Enzyme Differentially Influences the Intrarenal and Urinary Expression of Angiotensin Peptides
Published in Hypertension (Dallas, Tex. 1979) (01-04-2004)“…ABSTRACT—The relative contribution of circulating versus tissue renin-angiotensin systems to the tissue expression of angiotensin peptides in the kidney…”
Get full text
Journal Article -
10
Angiotensin II exerts positive feedback on the intrarenal renin-angiotensin system by an angiotensin converting enzyme-dependent mechanism
Published in The Journal of surgical research (01-12-2005)“…Plasma angiotensin II (ANG II) is not increased significantly in renovascular hypertension (RVH), but tissue ANG II levels are elevated in both kidneys of…”
Get full text
Journal Article -
11
Dopamine receptors and learned helplessness in the rat: An autoradiographic study
Published in Progress in neuro-psychopharmacology & biological psychiatry (01-05-2002)“…(1) Disturbances of mesolimbic and mesocortical dopamine (DA) function have been implicated in the pathophysiology of several psychiatric disorders, including…”
Get full text
Journal Article -
12
Nefazodone treatment for chronic posttraumatic stress disorder : An open trial
Published in Journal of clinical psychopharmacology (01-04-2000)“…Currently, there is no standard treatment for posttraumatic stress disorder (PTSD) because of a deficit of systematic treatment trials. The symptom overlap…”
Get full text
Journal Article -
13
Angiotensin Converting Enzyme-Independent Angiotensin II Production by Chymase is Up-regulated in the Ischemic Kidney in Renovascular Hypertension
Published in The Journal of surgical research (01-08-2005)“…Tissue angiotensin II (ANG II) levels are elevated in both kidneys in renovascular hypertension (RVH). It has been demonstrated previously that intrarenal ANG…”
Get full text
Journal Article -
14
Valproate therapy for chronic, combat-induced posttraumatic stress disorder
Published in Journal of clinical psychopharmacology (01-02-2002)Get full text
Journal Article -
15
Effects of learned helplessness on brain GABA receptors
Published in Neuroscience research (01-10-2000)“…GABA is involved in both clinical depression and in animal models of depression; however, the roles of GABA A and GABA B receptors in specific brain regions…”
Get full text
Journal Article -
16
Evaluation of a Gene-Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample
Published in Environmental health perspectives (01-05-2022)“…Consensus on the etiology of 1991 Gulf War illness (GWI) has been limited by lack of objective individual-level environmental exposure information and assumed…”
Get full text
Journal Article -
17
Low plasma gamma-aminobutyric acid levels during the late luteal phase of women with premenstrual dysphoric disorder
Published in The American journal of psychiatry (01-05-1996)“…Plasma gamma-aminobutyric acid (GABA) levels have been reported to be low in some patients with major depressive disorder. Premenstrual dysphoric disorder is…”
Get more information
Journal Article -
18
Evaluation of a Gene-Environment Interaction of PONI and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample
Published in Environmental health perspectives (01-05-2022)“…Background: Consensus on the etiology of 1991 Gulf War illness (GWI) has been limited by lack of objective individual- level environmental exposure information…”
Get full text
Journal Article -
19
The Ecological Fallacy Revisited: Aggregate- versus Individual-level Findings on Economics and Elections, and Sociotropic Voting
Published in The American political science review (01-03-1983)“…Several aggregate-level studies have found a relationship between macroeconomic conditions and election outcomes, operating in intuitively plausible…”
Get full text
Journal Article -
20
HAPTOGLOBIN COPY NUMBER VARIANTS DO NOT DIMINISH THE EFFECT OF CSL112 (APOA-I [HUMAN]) ON HDL FUNCTION
Published in Journal of the American College of Cardiology (02-04-2024)Get full text
Journal Article