Search Results - "Kramarova, Tatiana"
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Fragmentation Through Polymerization (FTP): A new method to fragment DNA for next-generation sequencing
Published in PloS one (01-04-2019)“…Fragmentation of DNA is the very important first step in preparing nucleic acids for next-generation sequencing. Here we report a novel Fragmentation Through…”
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Improved DOP-PCR (iDOP-PCR): A robust and simple WGA method for efficient amplification of low copy number genomic DNA
Published in PloS one (11-09-2017)“…Whole-genome amplification (WGA) techniques are used for non-specific amplification of low-copy number DNA, and especially for single-cell genome and…”
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Cold tolerance of UCP1-ablated mice: A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects
Published in Biochimica et biophysica acta (01-06-2010)“…Mice lacking the thermogenic mitochondrial membrane protein UCP1 (uncoupling protein 1) - and thus all heat production from brown adipose tissue - can still…”
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A strong strand displacement activity of thermostable DNA polymerase markedly improves the results of DNA amplification
Published in BioTechniques (01-08-2014)“…The sensitivity and robustness of various DNA detection and amplification techniques are to a large extent determined by the properties of the DNA polymerase…”
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The immunophilin-like protein XAP2 is a negative regulator of estrogen signaling through interaction with estrogen receptor α
Published in PloS one (03-10-2011)“…XAP2 (also known as aryl hydrocarbon receptor interacting protein, AIP) is originally identified as a negative regulator of the hepatitis B virus X-associated…”
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Uncoupling proteins: A role in protection against reactive oxygen species—or not?
Published in Biochimica et biophysica acta (01-05-2006)“…A physiological function of the original uncoupling protein, UCP1, is well established: UCP1 is the molecular background for nonshivering thermogenesis. The…”
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Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively
Published in Biochemical journal (01-11-2006)“…In brown-fat mitochondria, fatty acids induce thermogenic uncoupling through activation of UCP1 (uncoupling protein 1). However, even in brown-fat mitochondria…”
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The Environmental Pollutants Perfluorooctane Sulfonate and Perfluorooctanoic Acid Upregulate Uncoupling Protein 1 (UCP1) in Brown-Fat Mitochondria Through a UCP1-Dependent Reduction in Food Intake
Published in Toxicological sciences (01-08-2015)“…The environmental pollutants perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) cause a dramatic reduction in the size of the major adipose…”
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Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform
Published in The FASEB journal (01-01-2008)“…Despite the significance of mitochondrial ATP synthase for mammalian metabolism, the regulation of the amount of ATP synthase in mammalian systems is not…”
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Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Published in Clinical epigenetics (30-05-2019)“…Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are…”
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UCP1 and defense against oxidative stress. 4-Hydroxy-2-nonenal effects on brown fat mitochondria are uncoupling protein 1-independent
Published in The Journal of biological chemistry (19-05-2006)“…Uncoupling proteins have been ascribed a role in defense against oxidative stress, particularly by being activated by products of oxidative stress such as…”
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A sequence predicted to form a stem–loop is proposed to be required for formation of an RNA–protein complex involving the 3'UTR of β-subunit F0F1-ATPase mRNA
Published in Biochimica et biophysica acta (01-07-2008)“…ATP-synthase assembly requires coordinated control of ATP mRNA translation; this may e.g. occur through the formation of mRNA–protein complexes. In this study…”
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UCP1 and Defense against Oxidative Stress
Published in The Journal of biological chemistry (19-05-2006)“…Uncoupling proteins have been ascribed a role in defense against oxidative stress, particularly by being activated by products of oxidative stress such as…”
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14
Fragmentation Through Polymerization
Published in PloS one (01-04-2019)“…Fragmentation of DNA is the very important first step in preparing nucleic acids for next-generation sequencing. Here we report a novel Fragmentation Through…”
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Journal Article -
15
Next-generation sequencing identifies microRNAs that associate with pathogenic autoimmune neuroinflammation in rats
Published in The Journal of immunology (1950) (15-04-2013)“…MicroRNAs (miRNAs) are known to regulate most biological processes and have been found dysregulated in a variety of diseases, including multiple sclerosis…”
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Improved DOP-PCR
Published in PloS one (11-09-2017)“…Whole-genome amplification (WGA) techniques are used for non-specific amplification of low-copy number DNA, and especially for single-cell genome and…”
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Journal Article -
17
The Immunophilin-Like Protein XAP2 Is a Negative Regulator of Estrogen Signaling through Interaction with Estrogen Receptor [alpha]
Published in PloS one (03-10-2011)“…XAP2 (also known as aryl hydrocarbon receptor interacting protein, AIP) is originally identified as a negative regulator of the hepatitis B virus X-associated…”
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18
S5/1 Control of the synthesis of uncoupling and coupling proteins in brown adipose tissue
Published in Biochimica et biophysica acta. Bioenergetics (19-07-2008)Get full text
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The role of the estrogen receptors in obesity
Published in Drug discovery today. Disease mechanisms (2009)“…The incidence of obesity in the modern society has reached epidemic proportions and constitutes a great public health concern. Epidemiological, retrospective…”
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Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform
Published in The FASEB journal (2007)Get full text
Journal Article