Search Results - "Kralt, Annemarie"
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Natively Unfolded FG Repeats Stabilize the Structure of the Nuclear Pore Complex
Published in Cell (02-11-2017)“…Nuclear pore complexes (NPCs) are ∼100 MDa transport channels assembled from multiple copies of ∼30 nucleoporins (Nups). One-third of these Nups contain…”
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An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae
Published in eLife (24-08-2022)“…The nuclear pore complex (NPC) is the central portal for macromolecular exchange between the nucleus and cytoplasm. In all eukaryotes, NPCs assemble into an…”
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Intrinsically Disordered Linker and Plasma Membrane‐Binding Motif Sort Ist2 and Ssy1 to Junctions
Published in Traffic (Copenhagen, Denmark) (01-02-2015)“…Membrane junctions or contact sites are close associations of lipid bilayers of heterologous organelles. Ist2 is an endoplasmic reticulum (ER)‐resident…”
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Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins
Published in Molecular biology of the cell (15-09-2015)“…Endoplasmic reticulum-synthesized membrane proteins traffic through the nuclear pore complex (NPC) en route to the inner nuclear membrane (INM). Although many…”
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Mapping the native organization of the yeast nuclear pore complex using nuclear radial intensity measurements
Published in Proceedings of the National Academy of Sciences - PNAS (16-07-2019)“…Selective transport across the nuclear envelope (NE) is mediated by the nuclear pore complex (NPC), a massive ∼100-MDa assembly composed of multiple copies of…”
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Long Unfolded Linkers Facilitate Membrane Protein Import Through the Nuclear Pore Complex
Published in Science (American Association for the Advancement of Science) (01-07-2011)“…Active nuclear import of soluble cargo involves transport factors that shuttle cargo through the nuclear pore complex (NPC) by binding to phenylalanine-glycine…”
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