Search Results - "Kralic, Jason E."
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Spinal cord injury pharmacotherapy: Current research & development and competitive commercial landscape as of 2015
Published in The journal of spinal cord medicine (01-01-2019)“…Current treatment of spinal cord injury (SCI) focuses on cord stabilization to prevent further injury, rehabilitation, management of non-motor symptoms, and…”
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Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures
Published in The European journal of neuroscience (01-10-2005)“…Adult hippocampal neurogenesis is enhanced in response to multiple stimuli including seizures. However, the relationship between neurogenesis and the…”
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Impairment of dentate gyrus neuronal progenitor cell differentiation in a mouse model of temporal lobe epilepsy
Published in Experimental neurology (01-05-2006)“…Unilateral intrahippocampal injection of kainic acid (KA) in adult mice induces an epileptic focus replicating major histopathological features of temporal…”
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NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists
Published in Pharmacology, biochemistry and behavior (01-06-2003)“…Because extracts of kudzu have been used as a hangover remedy in China for many centuries, we tested the ability of NPI-031G (puerarin), an isoflavone isolated…”
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GABAA-Receptor δ Subunit Knockout Mice Have Multiple Defects in Behavioral Responses to Ethanol
Published in Alcoholism, clinical and experimental research (01-12-2001)“…Background: The γ‐aminobutyric acid type A receptors (GABARs) are involved in mediating some of the behavioral effects of beverage alcohol (ethanol). However,…”
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Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of γ-aminobutyric acid type A receptor α1 subunit knockout mice
Published in Journal of comparative neurology (1911) (01-04-2006)“…Targeted deletion of the α1 subunit gene results in a profound loss of γ‐aminobutyric acid type A (GABAA) receptors in adult mouse brain but has only moderate…”
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Genetic essential tremor in γ-aminobutyric acidA receptor α1 subunit knockout mice
Published in The Journal of clinical investigation (01-03-2005)“…Essential tremor is the most common movement disorder and has an unknown etiology. Here we report that γ-aminobutyric acid A (GABA A ) receptor α 1 –/– mice…”
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Differential Dependence of Axo-Dendritic and Axo-Somatic GABAergic Synapses on GABAA Receptors Containing the α1 Subunit in Purkinje Cells
Published in The Journal of neuroscience (22-03-2006)“…Synapse formation and maintenance require extensive transsynaptic interactions involving multiple signal transduction pathways. In the cerebellum, Purkinje…”
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Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear
Published in Molecular pharmacology (01-07-2005)“…Inhaled anesthetics are believed to produce anesthesia by their actions on ion channels. Because inhaled anesthetics robustly enhance GABA A receptor…”
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Differential Dependence of Axo-Dendritic and Axo-Somatic GABAergic Synapses on GABA A Receptors Containing the α1 Subunit in Purkinje Cells
Published in The Journal of neuroscience (22-03-2006)“…Synapse formation and maintenance require extensive transsynaptic interactions involving multiple signal transduction pathways. In the cerebellum, Purkinje…”
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Differential Dependence of Axo-Dendritic and Axo-Somatic GABAergic Synapses on GABA sub(A) Receptors Containing the alpha 1 Subunit in Purkinje Cells
Published in The Journal of neuroscience (01-03-2006)“…Synapse formation and maintenance require extensive transsynaptic interactions involving multiple signal transduction pathways. In the cerebellum, Purkinje…”
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13
Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice
Published in Journal of comparative neurology (1911) (01-04-2006)“…Targeted deletion of the alpha1 subunit gene results in a profound loss of gamma-aminobutyric acid type A (GABA(A)) receptors in adult mouse brain but has only…”
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Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of [gamma]-aminobutyric acid type A receptor [alpha]1 subunit knockout mice
Published in Journal of comparative neurology (1911) (01-01-2006)“…Targeted deletion of the [alpha]1 subunit gene results in a profound loss of [gamma]-aminobutyric acid type A (GABA sub(A)) receptors in adult mouse brain but…”
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Genetic essential tremor in [gamma]-aminobutyric acid^sub A^ receptor [alpha]1 subunit knockout mice
Published in The Journal of clinical investigation (01-03-2005)“…Essential tremor is the most common movement disorder and has an unknown etiology. Here we report that gamma-aminobutyric acidA (GABA(A)) receptor alpha1-/-…”
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Journal Article -
16
Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice
Published in The Journal of clinical investigation (01-03-2005)“…Essential tremor is the most common movement disorder and has an unknown etiology. Here we report that gamma-aminobutyric acidA (GABA(A)) receptor alpha1-/-…”
Get full text
Journal Article -
17
NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT 2C agonists
Published in Pharmacology, biochemistry and behavior (2003)“…Because extracts of kudzu have been used as a hangover remedy in China for many centuries, we tested the ability of NPI-031G (puerarin), an isoflavone isolated…”
Get full text
Journal Article -
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Chronic Blockade of N‐Methyl‐D‐Aspartate Receptors Alters γ‐Aminobutyric Acid Type A Receptor Peptide Expression and Function in the Rat
Published in Journal of neurochemistry (01-04-2000)“…: Chronic in vivo or in vitro application of GABAA receptor agonists alters GABAA receptor peptide expression and function. Furthermore, chronic in vitro…”
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Differential dependence of axo-dendritic and axo-somatic GABAergic synapses on GABAA receptors containing the alpha1 subunit in Purkinje cells
Published in The Journal of neuroscience (22-03-2006)“…Synapse formation and maintenance require extensive transsynaptic interactions involving multiple signal transduction pathways. In the cerebellum, Purkinje…”
Get full text
Journal Article