Search Results - "Krajewski, Stan"

Mitochondrial/Cell-Surface Protein p32/gC1qR as a Molecular Target in Tumor Cells and Tumor Stroma by FOGAL, Valentina, LIANGLIN ZHANG, KRAJEWSKI, Stan, RUOSLAHTI, Erkki

“…A tumor homing peptide, LyP-1, selectively binds to tumor-associated lymphatic vessels and tumor cells in certain tumors and exhibits an antitumor effect…”
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A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries by Mann, Aman P., Scodeller, Pablo, Hussain, Sazid, Joo, Jinmyoung, Kwon, Ester, Braun, Gary B., Mölder, Tarmo, She, Zhi-Gang, Kotamraju, Venkata Ramana, Ranscht, Barbara, Krajewski, Stan, Teesalu, Tambet, Bhatia, Sangeeta, Sailor, Michael J., Ruoslahti, Erkki

“…Traumatic brain injury (TBI) is a major health and socio-economic problem, but no pharmacological agent is currently approved for the treatment of acute TBI…”
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Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors by Qi, Jianfei, Nakayama, Koh, Cardiff, Robert D., Borowsky, Alexander D., Kaul, Karen, Williams, Roy, Krajewski, Stan, Mercola, Dan, Carpenter, Philip M., Bowtell, David, Ronai, Ze'ev A.

“…Neuroendocrine (NE) phenotype, seen in >30% of prostate adenocarcinomas (PCa), and NE prostate tumors are implicated in aggressive prostate cancer. Formation…”
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Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice by Niesman, Ingrid R, Schilling, Jan M, Shapiro, Lee A, Kellerhals, Sarah E, Bonds, Jacqueline A, Kleschevnikov, Alexander M, Cui, Weihua, Voong, April, Krajewski, Stan, Ali, Sameh S, Roth, David M, Patel, Hemal H, Patel, Piyush M, Head, Brian P

“…Traumatic brain injury (TBI) enhances pro-inflammatory responses, neuronal loss and long-term behavioral deficits. Caveolins (Cavs) are regulators of neuronal…”
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Plg-RKT Expression in Human Breast Cancer Tissues by Miles, Lindsey A., Krajewski, Stan, Baik, Nagyung, Parmer, Robert J., Mueller, Barbara M.

“…The plasminogen activation system regulates the activity of the serine protease, plasmin. The role of plasminogen receptors in cancer progression is being…”
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Calpain and Mitochondria in Ischemia/Reperfusion Injury by Chen, Min, Won, Dong-Jun, Krajewski, Stan, Gottlieb, Roberta A

“…Studies of ischemia/reperfusion (I/R) injury and preconditioning have shown that ion homeostasis, particularly calcium homeostasis, is critical to limiting…”
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ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways by Qi, Jianfei, Nakayama, Koh, Gaitonde, Supriya, Goydos, James S, Krajewski, Stan, Eroshkin, Alexey, Bar-Sagi, Dafna, Bowtell, David, Ronai, Ze'ev

“…The ubiquitin ligase Siah2 has been shown to regulate prolyl hydroxylase 3 (PHD3) stability with concomitant effect on HIF-1α availability. Because HIF-1α is…”
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Nonstripping "Rainbow" and Multiple Antigen Detection (MAD) Western Blotting by Krajewski, Stan Stanislaw, Tsukamoto, Michelle M, Huang, Xianshu, Krajewski, Sebastian B

“…A variation of immunoblotting method (the "Rainbow Western"), permits sequential detection of multiple antigens (MAD) on a single protein blot without…”
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Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity by Krajewska, Maryla, You, Zerong, Rong, Juan, Kress, Christina, Huang, Xianshu, Yang, Jinsheng, Kyoda, Tiffany, Leyva, Ricardo, Banares, Steven, Hu, Yue, Sze, Chia-Hung, Whalen, Michael J, Salmena, Leonardo, Hakem, Razqallah, Head, Brian P, Reed, John C, Krajewski, Stan

“…Acute brain injury is an important health problem. Given the critical position of caspase 8 at the crossroads of cell death pathways, we generated a new viable…”
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Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients by Staquicini, Fernanda I., Cardó-Vila, Marina, Kolonin, Mikhail G., Trepel, Martin, Edwards, Julianna K., Nunes, Diana N., Sergeeva, Anna, Efstathiou, Eleni, Sun, Jessica, Almeida, Nalvo F., Tu, Shi-Ming, Botz, Gregory H., Wallace, Michael J., O'Connell, David J., Krajewski, Stan, Gershenwald, Jeffrey E., Molldrem, Jeffrey J., Flamm, Anne L., Koivunen, Erkki, Pentz, Rebecca D., Dias-Neto, Emmanuel, Setubal, João C., Cahill, Dolores J., Troncoso, Patricia, Do, Kim-Ahn, Logothetis, Christopher J., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih

“…Molecules differentially expressed in blood vessels among organs or between damaged and normal tissues, are attractive therapy targets; however, their…”
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Preclinical Studies of Celastrol and Acetyl Isogambogic Acid in Melanoma by ABBAS, Sabiha, BHOUMIK, Anindita, DAHL, Russell, VASILE, Stefan, KRAJEWSKI, Stan, COSFORD, Nicholas D. P, RONAI, Zeev A

“…Purpose: Sensitize melanomas to apoptosis and inhibit their growth and metastatic potential by compounds that mimic the activities of activating transcription…”
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Bid Is Cleaved by Calpain to an Active Fragment in Vitro and during Myocardial Ischemia/Reperfusion by Chen, M, He, H, Zhan, S, Krajewski, S, Reed, J C, Gottlieb, R A

“…Reperfusion after myocardial ischemia is associated with a rapid influx of calcium, leading to activation of various enzymes including calpain. Isolated…”
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Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis by Lu, Zhi Hong, Shvartsman, Mark B, Lee, Andrew Y, Shao, Jenny M, Murray, Mollianne M, Kladney, Raleigh D, Fan, Dong, Krajewski, Stan, Chiang, Gary G, Mills, Gordon B, Arbeit, Jeffrey M

“…Small GTPase Ras homologue enriched in brain (RHEB) binds and activates the key metabolic regulator mTORC1, which has an important role in cancer cells, but…”
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Elevated Expression of Inhibitor of Apoptosis Proteins in Prostate Cancer by KRAJEWSKA, Maryla, KRAJEWSKI, Stan, GAO, Guo-Jian, REED, John C, BANARES, Steven, XIANSHU HUANG, TURNER, Bruce, BUBENDORF, Lukas, KAŁŁIONIEMI, Olli-P, SHABAIK, Ahmed, VITIELLO, Antonella, PEEHL, Donna

“…Purpose: Inhibitor of apoptosis (IAP) family proteins are suppressors of apoptosis that have been implicated in apoptosis resistance in some cancers. Their…”
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A role for ATF2 in regulating MITF and melanoma development by Shah, Meera, Bhoumik, Anindita, Goel, Vikas, Dewing, Antimone, Breitwieser, Wolfgang, Kluger, Harriet, Krajewski, Stan, Krajewska, Maryla, Dehart, Jason, Lau, Eric, Kallenberg, David M, Jeong, Hyeongnam, Eroshkin, Alexey, Bennett, Dorothy C, Chin, Lynda, Bosenberg, Marcus, Jones, Nic, Ronai, Ze'ev A

“…The transcription factor ATF2 has been shown to attenuate melanoma susceptibility to apoptosis and to promote its ability to form tumors in xenograft models…”
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"Rainbow" western blotting by Krajewski, Stan

“…The ''Rainbow western'' method permits detection of multiple antigens on a single protein blot. The procedure utilizes horseradish peroxidase (HRPase)-based…”
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Image Analysis Algorithms for Immunohistochemical Assessment of Cell Death Events and Fibrosis in Tissue Sections by Krajewska, Maryla, Smith, Layton H, Rong, Juan, Huang, Xianshu, Hyer, Marc L, Zeps, Nikolajs, Iacopetta, Barry, Linke, Steven P, Olson, Allen H, Reed, John C, Krajewski, Stan

“…Cell death is of broad physiological and pathological importance, making quantification of biochemical events associated with cell demise a high priority for…”
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Suppressor role of activating transcription factor 2 (ATF2) in skin cancer by Bhoumik, Anindita, Fichtman, Boris, DeRossi, Charles, Breitwieser, Wolfgang, Kluger, Harriet M, Davis, Sean, Subtil, Antonio, Meltzer, Paul, Krajewski, Stan, Jones, Nic, Ronai, Ze'ev

“…Activating transcription factor 2 (ATF2) regulates transcription in response to stress and growth factor stimuli. Here, we use a mouse model in which ATF2 was…”
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Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma by Luciano, Frederic, Krajewska, Maryla, Ortiz-Rubio, Paulina, Krajewski, Stan, Zhai, Dayong, Faustin, Benjamin, Bruey, Jean-Marie, Bailly-Maitre, Beatrice, Lichtenstein, Alan, Kolluri, Siva Kumar, Satterthwait, Arnold C., Zhang, Xiao-Kun, Reed, John C.

“…Defects in apoptosis mechanisms play important roles in malignancy and autoimmunity. Orphan nuclear receptor Nur77/TR3 has been demonstrated to bind…”
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Analysis of Apoptosis Protein Expression in Early-Stage Colorectal Cancer Suggests Opportunities for New Prognostic Biomarkers by Krajewska, Maryla, Kim, Hoguen, Kim, Chul, Kang, Haeyoun, Welsh, Kate, Matsuzawa, Shu-Ichi, Tsukamoto, Michelle, Thomas, Ronald G, Assa-Munt, Nuria, Piao, Zhe, Suzuki, Koichi, Perucho, Manuel, Krajewski, Stan, Reed, John C

“…Purpose: Although most stage II colon cancers are potentially curable by surgery alone, ∼20% of patients relapse, suggesting a need for establishing prognostic…”
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