Search Results - "Krahn, Murray D."

Estimation of stage‐specific fibrosis progression rates in chronic hepatitis C virus infection: A meta‐analysis and meta‐regression by Thein, Hla‐Hla, Yi, Qilong, Dore, Gregory J., Krahn, Murray D.

“…Published estimates of liver fibrosis progression in individuals with chronic hepatitis C virus (HCV) infection are heterogeneous. We aimed to estimate…”
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A province-by-province cost-effectiveness analysis and budget impact analysis of one-time birth cohort screening of hepatitis C virus (HCV) infection in Canada by Wong, William W. L., Haines, Alex, Wong, Josephine, Hamadeh, Abdullah, Krahn, Murray D.

“…Managing chronic hepatitis C is challenging, as the majority of those infected are asymptomatic. Therefore, to ensure treatments are administered before the…”
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Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy : a meta-analysis by THEIN, Hla-Hla, QILONG YI, DORE, Gregory J, KRAHN, Murray D

“…To estimate stage-specific transition probabilities in individuals coinfected with HIV and hepatitis C virus (HCV), to examine the effect of covariates on…”
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The impact of the early COVID-19 pandemic on healthcare system resource use and costs in two provinces in Canada: An interrupted time series analysis by Zeitouny, Seraphine, Cheung, Douglas C, Bremner, Karen E, Pataky, Reka E, Pequeno, Priscila, Matelski, John, Peacock, Stuart, Del Giudice, M. Elisabeth, Lapointe-Shaw, Lauren, Tomlinson, George, Mendlowitz, Andrew B, Mulder, Carol, Tsui, Teresa C. O, Perlis, Nathan, Walker, Jennifer D, Sander, Beate, Wong, William W. L, Krahn, Murray D, Kulkarni, Girish S

“…Introduction The aim of our study was to assess the initial impact of COVID-19 on total publicly-funded direct healthcare costs and health services use in two…”
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Developing the Breast Utility Instrument, a preference-based instrument to measure health-related quality of life in women with breast cancer: Confirmatory factor analysis of the EORTC QLQ-C30 and BR45 to establish dimensions by Tsui, Teresa C O, Trudeau, Maureen, Mitsakakis, Nicholas, Torres, Sofia, Bremner, Karen E, Kim, Doyoung, Davis, Aileen M, Krahn, Murray D

“…Breast cancer (BrC) and its treatments impair health-related quality of life (HRQoL). Utility is a measure of HRQoL that includes preferences for health…”
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A scoping review to create a framework for the steps in developing condition-specific preference-based instruments de novo or from an existing non-preference-based instrument: use of item response theory or Rasch analysis by Tsui, Teresa C O, Torres, Sofia C, Bielecki, Joanna M, Mitsakakis, Nicholas, Trudeau, Maureen E, Bremner, Karen E, Davis, Aileen M, Krahn, Murray D

“…There is no widely accepted framework to guide the development of condition-specific preference-based instruments (CSPBIs) that includes both de novo and from…”
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Costs for Childhood and Adolescent Cancer, 90 Days Prediagnosis and 1 Year Postdiagnosis: A Population-Based Study in Ontario, Canada by de Oliveira, Claire, PhD, Bremner, Karen E., BSc, Liu, Ning, MSc, Greenberg, Mark L., MD, Nathan, Paul C., MD, MSc, McBride, Mary L., MSc, Krahn, Murray D., MD, MSc

“…Abstract Background Childhood and adolescent cancers are uncommon, but they have important economic and health impacts on patients, families, and health care…”
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End-of-Life Care for Lung Cancer Patients in the United States and Ontario by WARREN, Joan L, BARBERA, Lisa, BREMNER, Karen E, YABROFF, K. Robin, HOCH, Jeffrey S, BARRETT, Michael J, LUO, Jin, KRAHN, Murray D

“…Both the United States and Canada offer government-financed health insurance for the elderly, but few studies have compared care at the end of life for cancer…”
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Influence of socioeconomic status on survival of hepatocellular carcinoma in the Ontario population; a population-based study, 1990-2009 by Jembere, Nathaniel, Campitelli, Michael A, Sherman, Morris, Feld, Jordan J, Lou, Wendy, Peacock, Stuart, Yoshida, Eric, Krahn, Murray D, Earle, Craig, Thein, Hla-Hla

“…Research has shown that people from higher socioeconomic status (SES) have better hepatocellular carcinoma (HCC) survival outcomes, although no such research…”
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Benefits and harms of prostate cancer screening - predictions of the ONCOTYROL prostate cancer outcome and policy model by Mühlberger, Nikolai, Boskovic, Kristijan, Krahn, Murray D, Bremner, Karen E, Oberaigner, Willi, Klocker, Helmut, Horninger, Wolfgang, Sroczynski, Gaby, Siebert, Uwe

“…A recent recalibration of the ONCOTYROL Prostate Cancer Outcome and Policy (PCOP) Model, assuming that latent prostate cancer (PCa) detectable at autopsy might…”
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Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials by Wong, William W L, Pechivanoglou, Petros, Wong, Josephine, Bielecki, Joanna M, Haines, Alex, Erman, Aysegul, Saeed, Yasmin, Phoon, Arcturus, Tadrous, Mina, Younis, Mona, Rayad, Noha Z, Rac, Valeria, Janssen, Harry L A, Krahn, Murray D

“…Chronic hepatitis B (CHB) infection poses a significant burden to public health worldwide. Most cases are clinically silent until late in the disease course…”
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Developing the Breast Utility Instrument to Measure Health-Related Quality-of-Life Preferences in Patients with Breast Cancer: Selecting the Item for Each Dimension by Tsui, Teresa C. O., Trudeau, Maureen E., Mitsakakis, Nicholas, Krahn, Murray D., Davis, Aileen M.

“…Introduction. Generic preference-based instruments inadequately measure breast cancer (BrC) health-related quality-of-life preferences given advances in…”
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Cost-Utility Analysis of Primary Prophylaxis Versus Secondary Prophylaxis With Granulocyte Colony-Stimulating Factor in Elderly Patients With Diffuse Aggressive Lymphoma Receiving Curative-Intent Chemotherapy by CHAN, Kelvin K. W, SIU, Eric, KRAHN, Murray D, IMRIE, Kevin, ALIBHAI, Shabbir M. H

“…The 2006 American Society of Clinical Oncology (ASCO) guideline recommended primary prophylaxis (PP) with granulocyte colony-stimulating factor (G-CSF) instead…”
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Do Older Men Benefit From Curative Therapy of Localized Prostate Cancer? by ALIBHAI, Shabbir M. H, NAGLIE, Gary, NAM, Robert, TRACHTENBERG, John, KRAHN, Murray D

“…Prior decision-analytic models are based on outdated or suboptimal efficacy, patient preference, and comorbidity data. We estimated life expectancy (LE) and…”
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Health-Related Quality of Life Changes Associated With Hearing Loss by Dixon, Peter R, Feeny, David, Tomlinson, George, Cushing, Sharon, Chen, Joseph M, Krahn, Murray D

“…Utility is a single-value, preference-based measure of health-related quality of life that represents the desirability of a health state relative to being dead…”
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Pharmacotherapy vs surgery as initial therapy for patients with moderate‐to‐severe benign prostate hyperplasia: a cost‐effectiveness analysis by Erman, Aysegul, Masucci, Lisa, Krahn, Murray D., Elterman, Dean S.

“…Objective To evaluate the cost‐effectiveness of using a surgery, such as transurethral resection of the prostate (TURP) or photoselective vaporisation of the…”
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Using a Health Economic Framework to Prioritize Quality Indicators: An Example With Smoking Cessation in Chronic Obstructive Pulmonary Disease by Nam, Austin, Naimark, David M. J., Stanbrook, Matthew B., Krahn, Murray D.

“…Background. Health care performance monitoring is a major focus of the modern quality movement, resulting in widespread development of quality indicators and…”
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Does cirrhosis affect quality of life in hepatitis C virus-infected patients? by Hsu, Priscilla C., Krajden, Mel, Yoshida, Eric M., Anderson, Frank H., Tomlinson, George A., Krahn, Murray D.

“…Background: Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and is associated with impairments in health‐related quality of life…”
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Valuing Health State: An EQ-5D-5L Value Set for Ethiopians by Welie, Abraham G., Gebretekle, Gebremedhin Beedemariam, Stolk, Elly, Mukuria, Clara, Krahn, Murray D., Enquoselassie, Fikre, Fenta, Teferi Gedif

“…There is a growing interest in health technology assessment and economic evaluations in developing countries such as Ethiopia. The objective of this study was…”
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Impact of direct‐acting antiviral regimens on mortality and morbidity outcomes in patients with chronic hepatitis c: Systematic review and meta‐analysis by Sahakyan, Yeva, Lee‐Kim, Victoria, Bremner, Karen E., Bielecki, Joanna M., Krahn, Murray D.

“…The long‐term effects of direct‐acting antiviral therapies (DAAs) for chronic hepatitis C (CHC) remain uncertain. The objective of this systematic review and…”
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