Search Results - "Krag, Aleksander"

Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure by Trebicka, Jonel, Bork, Peer, Krag, Aleksander, Arumugam, Manimozhiyan

“…The human gut microbiome has emerged as a major player in human health and disease. The liver, as the first organ to encounter microbial products that cross…”
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Artificial intelligence outperforms standard blood-based scores in identifying liver fibrosis patients in primary care by Blanes-Vidal, Victoria, Lindvig, Katrine P., Thiele, Maja, Nadimi, Esmaeil S., Krag, Aleksander

“…For years, hepatologists have been seeking non-invasive methods able to detect significant liver fibrosis. However, no previous algorithm using routine blood…”
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Refining the Baveno VI elastography criteria for the definition of compensated advanced chronic liver disease by Papatheodoridi, Margarita, Hiriart, Jean Baptiste, Lupsor-Platon, Monica, Bronte, Fabrizio, Boursier, Jerome, Elshaarawy, Omar, Marra, Fabio, Thiele, Maja, Markakis, Georgios, Payance, Audrey, Brodkin, Edgar, Castera, Laurent, Papatheodoridis, George, Krag, Aleksander, Arena, Umberto, Mueller, Sebastian, Cales, Paul, Calvaruso, Vincenza, de Ledinghen, Victor, Pinzani, Massimo, Tsochatzis, Emmanuel A.

“…The Baveno VI consensus proposed a dual liver stiffness (LS) by transient elastography threshold of <10 and >15 kPa for excluding and diagnosing compensated…”
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Transient and 2-Dimensional Shear-Wave Elastography Provide Comparable Assessment of Alcoholic Liver Fibrosis and Cirrhosis by Thiele, Maja, Detlefsen, Sönke, Sevelsted Møller, Linda, Madsen, Bjørn Stæhr, Fuglsang Hansen, Janne, Fialla, Annette Dam, Trebicka, Jonel, Krag, Aleksander

“…Background & Aims Alcohol abuse causes half of all deaths from cirrhosis in the West, but few tools are available for noninvasive diagnosis of alcoholic liver…”
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Assessment of biopsy‐proven liver fibrosis by two‐dimensional shear wave elastography: An individual patient data‐based meta‐analysis by Herrmann, Eva, de Lédinghen, Victor, Cassinotto, Christophe, Chu, Winnie C.‐W., Leung, Vivian Y.‐F., Ferraioli, Giovanna, Filice, Carlo, Castera, Laurent, Vilgrain, Valérie, Ronot, Maxime, Dumortier, Jérôme, Guibal, Aymeric, Pol, Stanislas, Trebicka, Jonel, Jansen, Christian, Strassburg, Christian, Zheng, Rongqin, Zheng, Jian, Francque, Sven, Vanwolleghem, Thomas, Vonghia, Luisa, Manesis, Emanuel K., Zoumpoulis, Pavlos, Sporea, Ioan, Thiele, Maja, Krag, Aleksander, Cohen‐Bacrie, Claude, Criton, Aline, Gay, Joel, Deffieux, Thomas, Friedrich‐Rust, Mireen

“…Two‐dimensional shear wave elastography (2D‐SWE) has proven to be efficient for the evaluation of liver fibrosis in small to moderate‐sized clinical trials. We…”
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Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis by Israelsen, Mads, Juel, Helene Bæk, Detlefsen, Sönke, Madsen, Bjørn Stæhr, Rasmussen, Ditlev Nytoft, Larsen, Trine R., Kjærgaard, Maria, Fernandes Jensen, Mary Jo, Stender, Stefan, Hansen, Torben, Krag, Aleksander, Thiele, Maja

“…Individual risk for developing alcohol-related liver disease (ALD) varies greatly. We hypothesized that metabolic risk factors and genetic polymorphisms…”
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Systematic review of randomized trials on vasoconstrictor drugs for hepatorenal syndrome by Gluud, Lise L., Christensen, Kurt, Christensen, Erik, Krag, Aleksander

“…Vasoconstrictor drugs may improve renal function in hepatorenal syndrome (HRS), but the effect on mortality has not been established. We therefore performed a…”
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Advocating for the implementation of the new nomenclature for steatotic liver disease: A call to action for the national associations by Russo, Francesco Paolo, Francque, Sven M., Shawcross, Debbie L., Krag, Aleksander A.

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Nutritional therapy in cirrhosis or alcoholic hepatitis: a systematic review and meta-analysis by Fialla, Annette D., Israelsen, Mads, Hamberg, Ole, Krag, Aleksander, Gluud, Lise Lotte

“…Background & Aims Patients with cirrhosis and alcoholic hepatitis are often malnourished and have a superimposed stress metabolism, which increases nutritional…”
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Transcriptional Dynamics of Hepatic Sinusoid‐Associated Cells After Liver Injury by Terkelsen, Mike K., Bendixen, Sofie M., Hansen, Daniel, Scott, Emma A.H., Moeller, Andreas F., Nielsen, Ronni, Mandrup, Susanne, Schlosser, Anders, Andersen, Thomas L., Sorensen, Grith L., Krag, Aleksander, Natarajan, Kedar N., Detlefsen, Sönke, Dimke, Henrik, Ravnskjaer, Kim

“…Background and Aims Hepatic sinusoidal cells are known actors in the fibrogenic response to injury. Activated hepatic stellate cells (HSCs), liver sinusoidal…”
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Endotrophin and C6Ma3, serological biomarkers of type VI collagen remodelling, reflect endoscopic and clinical disease activity in IBD by Lindholm, Majken, Godskesen, Line E., Manon-Jensen, Tina, Kjeldsen, Jens, Krag, Aleksander, Karsdal, Morten A., Mortensen, Joachim H.

“…In inflammatory bowel disease (IBD), the chronic inflammation deeply affects the intestinal extracellular matrix. The aim of this study was to investigate if…”
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Is the Total Amount as Important as Localization and Type of Collagen in Liver Fibrosis Attributable to Steatohepatitis? by Karsdal, Morten A., Detlefsen, Sönke, Daniels, Samuel J., Nielsen, Mette J., Krag, Aleksander, Schuppan, Detlef

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Shear‐wave elastography of the liver and spleen identifies clinically significant portal hypertension: A prospective multicentre study by Jansen, Christian, Bogs, Christopher, Verlinden, Wim, Thiele, Maja, Möller, Philipp, Görtzen, Jan, Lehmann, Jennifer, Vanwolleghem, Thomas, Vonghia, Luisa, Praktiknjo, Michael, Chang, Johannes, Krag, Aleksander, Strassburg, Christian P., Francque, Sven, Trebicka, Jonel

“…Background & Aims Clinically significant portal hypertension (CSPH) is associated with severe complications and decompensation of cirrhosis. Liver stiffness…”
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Controlled attenuation parameter and alcoholic hepatic steatosis: Diagnostic accuracy and role of alcohol detoxification by Thiele, Maja, Rausch, Vanessa, Fluhr, Gabriele, Kjærgaard, Maria, Piecha, Felix, Mueller, Johannes, Straub, Beate Katharina, Lupșor-Platon, Monica, De-Ledinghen, Victor, Seitz, Helmut Karl, Detlefsen, Sönke, Madsen, Bjørn, Krag, Aleksander, Mueller, Sebastian

“…[Display omitted] •CAP performed better in the determination of steatosis than regular ultrasonography.•CAP can be used to detect severe alcoholic steatosis…”
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Ending stigmatizing language in alcohol and liver disease: a liver societies’ statement by Terrault, Norah A., Castro-Narro, Graciela, Krag, Aleksander, Shiina, Shuichiro

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Assessment of hepatic steatosis by controlled attenuation parameter using the M and XL probes: an individual patient data meta-analysis by Petroff, David, Blank, Valentin, Newsome, Philip N, Shalimar, Voican, Cosmin Sebastian, Thiele, Maja, de Lédinghen, Victor, Baumeler, Stephan, Chan, Wah Kheong, Perlemuter, Gabriel, Cardoso, Ana-Carolina, Aggarwal, Sandeep, Sasso, Magali, Eddowes, Peter J, Allison, Michael, Tsochatzis, Emmanuel, Anstee, Quentin M, Sheridan, David, Cobbold, Jeremy F, Naveau, Sylvie, Lupsor-Platon, Monica, Mueller, Sebastian, Krag, Aleksander, Irles-Depe, Marie, Semela, David, Wong, Grace Lai-Hung, Wong, Vincent Wai-Sun, Villela-Nogueira, Cristiane A, Garg, Harshit, Chazouillères, Olivier, Wiegand, Johannes, Karlas, Thomas

“…Diagnostic tools for liver disease can now include estimation of the grade of hepatic steatosis (S0 to S3). Controlled attenuation parameter (CAP) is a…”
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Non-selective beta-blockers may reduce risk of hepatocellular carcinoma: a meta-analysis of randomized trials by Thiele, Maja, Albillos, Agustín, Abazi, Rozeta, Wiest, Reiner, Gluud, Lise L., Krag, Aleksander

“…Background & Aims Non‐selective beta‐blockers (NSBB) are used in patients with cirrhosis and oesophageal varices. Experimental data suggest that NSBB inhibit…”
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Alcoholic liver disease: A registry view on comorbidities and disease prediction by Grissa, Dhouha, Nytoft Rasmussen, Ditlev, Krag, Aleksander, Brunak, Søren, Juhl Jensen, Lars

“…Alcoholic-related liver disease (ALD) is the cause of more than half of all liver-related deaths. Sustained excess drinking causes fatty liver and…”
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A global action agenda for turning the tide on fatty liver disease by Lazarus, Jeffrey V, Mark, Henry E, Allen, Alina M, Arab, Juan Pablo, Carrieri, Patrizia, Noureddin, Mazen, Alazawi, William, Alkhouri, Naim, Alqahtani, Saleh A, Anstee, Quentin M, Arrese, Marco, Bataller, Ramon, Berg, Thomas, Brennan, Paul N, Burra, Patrizia, Castro-Narro, Graciela E, Cortez-Pinto, Helena, Cusi, Kenneth, Dedes, Nikos, Duseja, Ajay, Francque, Sven M, Gastaldelli, Amalia, Hagström, Hannes, Huang, Terry T K, Ivancovsky Wajcman, Dana, Kautz, Achim, Kopka, Christopher J, Krag, Aleksander, Newsome, Philip N, Rinella, Mary E, Romero, Diana, Sarin, Shiv Kumar, Silva, Marcelo, Spearman, C Wendy, Terrault, Norah A, Tsochatzis, Emmanuel A, Valenti, Luca, Villota-Rivas, Marcela, Zelber-Sagi, Shira, Schattenberg, Jörn M, Wong, Vincent Wai-Sun, Younossi, Zobair M

“…Fatty liver disease is a major public health threat due to its very high prevalence and related morbidity and mortality. Focused and dedicated interventions…”
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P47 Cognitive Impairment in Obesity and NAFLD: A Cross-Sectional Study of 180 Patients With Multi-Domaine Cognitive Testing and Liver Biopsy by Wernberg, Charlotte Wilhelmina, Grønkjær, Lea Ladegaard, Gade, Birgitte, Chandran, Vineesh Indira, Krag, Aleksander, Graversen, Jonas Heilskov, Weissenborn, Karin, Vilstrup, Hendrik, Lauridsen, Mette Munk

“…Methods: A cross-sectional study of patients with a body mass index ≥of 35 kg/m under evaluation for bariatric surgery. There were no associations between…”
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