Search Results - "Kraft, Philip"
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Design and Enantioselective Synthesis of Cashmeran Odorants by Using "Enol Catalysis"
Published in Angewandte Chemie International Edition (02-02-2015)“…Novel Cashmeran odorants were designed by molecular modeling. Their short syntheses involve a novel asymmetric Brønsted acid catalyzed Michael addition of…”
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Primary-Amine-Catalyzed Enantioselective Intramolecular Aldolizations
Published in Angewandte Chemie (International ed.) (22-09-2008)“…Aldol cyclodehydration of 4‐substituted‐2,6‐heptanediones leads to enantiomerically enriched 5‐substituted‐3‐methyl‐2‐cyclohexene‐1‐ones, which serve as…”
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3
The Smelling Principle of Vetiver Oil, Unveiled by Chemical Synthesis
Published in Angewandte Chemie International Edition (08-03-2021)“…Vetiver oil, produced on a multiton‐scale from the roots of vetiver grass, is one of the finest and most popular perfumery materials, appearing in over a third…”
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Evidence for a shape-based recognition of odorants in vivo in the human nose from an analysis of the molecular mechanism of lily-of-the-valley odorants detection in the Lilial and Bourgeonal family using the C/Si/Ge/Sn switch strategy
Published in PloS one (01-08-2017)“…We performed an analysis of possible mechanisms of ligand recognition in the human nose. The analysis is based on in vivo odor threshold determination and in…”
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5
The Serendipitous Discovery of a Rose Odorant
Published in Chimia (29-04-2020)“…Serendipity has played a role in many groundbreaking scientific discoveries. Key to their identification and exploitation is the ability to recognize the…”
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On the Dienone Motif of Musks: Synthesis and Olfactory Properties of Partially and Fully Hydrogenated Dienone Musks
Published in European journal of organic chemistry (01-01-2014)“…Minimum‐energy calculations and the conformation of the (11Z)‐retinylidium moiety in bovine rhodopsin called into doubt that the function of the dienone motif…”
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Sila-rhubafuran and Derivatives: Synthesis and Olfactory Characterization of Novel Silicon-Containing Odorants
Published in Organometallics (13-01-2014)“…Sila-rhubafuran (1b), a silicon analogue of the grapefruit odorant rhubafuran (1a), was synthesized and isolated as a 1:1 mixture of two racemic diastereomers…”
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Efficient Macrocyclization by a Novel Oxy-Oxonia-Cope Reaction: Synthesis and Olfactory Properties of New Macrocyclic Musks
Published in Chemistry : a European journal (04-06-2012)“…Musk made to odor: A new oxy‐oxonia‐Cope macrocyclization to (3Z)‐configured cycloalk‐3‐en‐1‐yl formates is reported, which is useful in the synthesis of…”
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The Enantioselectivity of Odor Sensation: Some Examples for Undergraduate Chemistry Courses
Published in Journal of chemical education (01-06-2010)“…This article discusses seven chiral odorants that demonstrate the enantioselectivity of odor sensation: carvone, Celery Ketone, camphor, Florhydral,…”
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Synthesis and Olfactory Characterization of Novel Silicon-Containing Acyclic Dienone Musk Odorants
Published in European Journal of Inorganic Chemistry (01-06-2011)“…With an odor threshold value of 0.54 ng L–1 air, (3E,5E)‐7,7‐dimethyl‐5‐tert‐butylocta‐3,5‐dien‐2‐one (1a) constitutes the most potent member of a new family…”
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Book Review Journal Article -
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Disila-Galaxolide and Derivatives: Synthesis and Olfactory Characterization of Silicon-Containing Derivatives of the Musk Odorant Galaxolide
Published in Chemistry : a European journal (19-08-2013)“…A series of silicon‐containing derivatives of the polycyclic musk odorant galaxolide (4 a) was synthesized, that is, disila‐galaxolide ((4RS,7SR)‐4…”
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From Cassyrane to Cashmeran - The Molecular Parameters of Odorants
Published in Chemistry & biodiversity (01-10-2014)“…This review, including some new experimental results, is the summary of a talk at the ‘flavors & fragrances 2013’ conference in Leipzig, organized jointly by…”
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A Novel Oxy-Oxonia(Azonia)-Cope Reaction: Serendipitous Discovery and Its Application to the Synthesis of Macrocyclic Musks
Published in Chemistry & biodiversity (01-10-2014)“…This brief review, including new experimental results, is the summary of a talk at the GDCh conference ‘flavors & fragrances 2013’ in Leipzig, Germany,…”
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Disila-Phantolide and Derivatives: Synthesis and Olfactory Characterization of Silicon-Containing Derivatives of the Musk Odorant Phantolide
Published in Organometallics (24-08-2009)“…1-(1,1,2,3,3,6-Hexamethyl-1,3-disilaindan-5-yl)ethanone (disila-phantolide, 4), a disila-analogue of the musk odorant phantolide (3), and its…”
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Optically Active Ionones and Derivatives: Preparation and Olfactory Properties
Published in European journal of organic chemistry (01-03-2002)“…The isomeric ionones 1−3 are of both academic and commercial interest. Since their first preparation at the end of the 19th century they have been widely used…”
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The Odor Value Concept in the Formal Analysis of Olfactory Art
Published in Helvetica chimica acta (01-01-2019)“…In the past 15 years, there has been a tremendous increase in the emergence of olfactory artworks despite the traditional skepticism with respect to scents as…”
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17
'Brain Aided' Musk Design
Published in Chemistry & biodiversity (01-12-2004)“…This brief review, including new experimental results, is the summary of a talk at the RSC/SCI conference flavours & fragrances 2004 in Manchester, United…”
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Journal Article Conference Proceeding -
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Sniffing Out the Sustainable Future: The Renewability Revolution in Fragrance Chemistry
Published in Chemistry : a European journal (02-04-2024)“…In this review, the impact of the transition from today's petrochemical economy towards a 100/100 renewable and biodegradable future is discussed: "citrus",…”
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Front Cover: Sniffing Out the Sustainable Future: The Renewability Revolution in Fragrance Chemistry (Chem. Eur. J. 19/2024)
Published in Chemistry : a European journal (02-04-2024)“…The 100/100 world of perfumes: Perfumery is currently experiencing its most radical change since the introduction of synthetic vanillin 150 years ago: The…”
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Fragrance Chemistry — Milestones and Perspectives
Published in Chimia (30-05-2001)“…This mini-review on Fragrance Chemistry focuses on milestones in the timelines of musk, ionone/ woody and sandalwood odorants, as well as on new perspectives…”
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