Search Results - "Kraft, Anke R."
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COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses
Published in Immunity (Cambridge, Mass.) (09-02-2021)“…Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and correlates with severity of disease. The role of SARS-CoV-2-specific…”
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Attenuated effector T cells are linked to control of chronic HBV infection
Published in Nature immunology (01-09-2024)“…Hepatitis B virus (HBV)-specific CD8 + T cells play a dominant role during acute-resolving HBV infection but are functionally impaired during chronic HBV…”
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Hepatitis B virus-specific T cell responses after stopping nucleos(t)ide analogue therapy in HBeAg-negative chronic hepatitis B
Published in Journal of hepatology (01-09-2018)“…[Display omitted] •Discontinuation of NA therapy leads to higher HBsAg loss rates in HBeAg-negative CHB patients.•T cells from patients with subsequent HBsAg…”
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Hepatitis E virus-induced primary cutaneous CD30(+) T cell lymphoproliferative disorder
Published in Journal of hepatology (01-12-2017)“…[Display omitted] Several types of unexplained extra-hepatic manifestations, including haematological disorders, have been reported in the context of hepatitis…”
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5
Individual Epitope-Specific CD8 + T Cell Immune Responses Are Shaped Differently during Chronic Viral Infection
Published in Pathogens (Basel) (14-05-2023)“…A hallmark in chronic viral infections are exhausted antigen-specific CD8 T cell responses and the inability of the immune system to eliminate the virus…”
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Kinetics of CD8+ effector T cell responses and induced CD4+ regulatory T cell responses during Friend retrovirus infection
Published in European journal of immunology (01-10-2006)“…Cytolytic CD8+ T cells are critical for the control of acute Friend virus (FV) infection yet they fail to completely eliminate the virus during chronic…”
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PC61 (Anti-CD25) Treatment Inhibits Influenza A Virus-Expanded Regulatory T Cells and Severe Lung Pathology during a Subsequent Heterologous Lymphocytic Choriomeningitis Virus Infection
Published in Journal of Virology (01-12-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Frequency, Private Specificity, and Cross-Reactivity of Preexisting Hepatitis C Virus (HCV)-Specific CD8+ T Cells in HCV-Seronegative Individuals: Implications for Vaccine Responses
Published in Journal of virology (01-08-2015)“…T cell responses play a critical role in controlling or clearing viruses. Therefore, strategies to prevent or treat infections include boosting T cell…”
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Soluble immune markers in the different phases of chronic hepatitis B virus infection
Published in Scientific reports (01-10-2019)“…Chronic hepatitis B virus (HBV) infection may follow four different consecutive phases, which are defined by virology as well as biochemical markers and differ…”
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Cross-Reactive T Cell Response Exists in Chronic Lymphocytic Choriomeningitis Virus Infection upon Pichinde Virus Challenge
Published in Viruses (01-10-2022)“…Immunological memory to a previously encountered pathogen can influence the outcome of a sequential infection, which is called heterologous immunity…”
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Expanded regulatory T cells in chronically friend retrovirus-infected mice suppress immunity to a murine cytomegalovirus superinfection
Published in Journal of virology (01-12-2014)“…It is still unclear whether expanded and activated regulatory T cells (Tregs) in chronic viral infections can influence primary immune responses against…”
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Regulatory T cells resist virus infection-induced apoptosis
Published in Journal of virology (01-02-2015)“…Regulatory T (Treg) cells are important in the maintenance of self-tolerance, and the depletion of Treg cells correlates with autoimmune development. It has…”
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13
MitoTempo treatment as an approach to cure persistent viral infections?
Published in Virology (New York, N.Y.) (01-12-2024)“…Chronic viral infections are characterized by exhausted virus-specific T cells. Exhaustion is associated with mitochondrial dysfunction, revealing a possible…”
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14
Altered effector functions of NK cells in chronic hepatitis C are associated with IFNL3 polymorphism
Published in Journal of leukocyte biology (01-08-2015)“…IFNL3 polymorphism differentially influences NK cell functions upon IFN‐α stimulation; the role of NK cells may differ in chronic infection vs. early antiviral…”
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15
Viral and Host Responses After Stopping Long-term Nucleos(t)ide Analogue Therapy in HBeAg-Negative Chronic Hepatitis B
Published in The Journal of infectious diseases (15-11-2016)“…This prospective study investigated viral and host markers after stopping long-term therapy with nucleos(t)ide analogues in noncirrhotic patients with…”
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Reverse inflammaging: Long-term effects of HCV cure on biological age
Published in Journal of hepatology (01-01-2023)“…Chronic hepatitis C virus (HCV) infection can be cured with direct-acting antivirals (DAAs). However, not all sequelae of chronic hepatitis C appear to be…”
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Application of CT contrast medium is not associated with an increased risk for acute kidney injury in patients with decompensated cirrhosis
Published in Alimentary pharmacology & therapeutics (01-01-2023)“…Summary Background Acute kidney injury (AKI) is a frequent complication in patients with decompensated cirrhosis. Studies reported conflicting results…”
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18
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?
Published in Current opinion in immunology (01-06-2023)“…Hepatitis C virus (HCV) infection provides a unique opportunity to study the effects of spontaneous or treatment-induced viral elimination on the human immune…”
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Impending HCC diagnosis in patients with cirrhosis after HCV cure features a natural killer cell signature
Published in Hepatology (Baltimore, Md.) (01-07-2024)“…The risk of developing HCC in chronically infected patients with AQ2 HCV with liver cirrhosis is significantly elevated. This risk remains high even after a…”
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CpG oligodeoxynucleotides allow for effective adoptive T-cell therapy in chronic retroviral infection
Published in Blood (01-04-2007)“…Adoptive T-cell therapy in cancer or chronic viral infections is often impeded by the development of functional impairment of the transferred cells. To…”
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