Search Results - "Kraemer, Thomas"
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Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
Published in Nature (London) (30-10-2014)“…A mutation in VRC01, a broadly neutralizing, HIV-1-specific antibody, confers enhanced binding to the neonatal Fc receptor, increasing the antibody half-life…”
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2
Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome
Published in Gut (01-07-2017)“…Western lifestyle and diet are major environmental factors playing a role in the development of IBD. Titanium dioxide (TiO ) nanoparticles are widely used as…”
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3
Metabolomic Strategies in Biomarker Research-New Approach for Indirect Identification of Drug Consumption and Sample Manipulation in Clinical and Forensic Toxicology?
Published in Frontiers in chemistry (10-05-2019)“…Drug of abuse (DOA) consumption is a growing problem worldwide, particularly with increasing numbers of new psychoactive substances (NPS) entering the drug…”
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4
Geochemical and isotopic evolution of water produced from Middle Devonian Marcellus Shale gas wells, Appalachian Basin, Pennsylvania
Published in AAPG bulletin (01-02-2015)“…The number of Marcellus Shale gas wells drilled in the Appalachian basin has increased rapidly over the past decade, leading to increased interest in the…”
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5
Deep Semisupervised Teacher-Student Model Based on Label Propagation for Sea Ice Classification
Published in IEEE journal of selected topics in applied earth observations and remote sensing (2021)“…In this article, we propose a novelteacher-student-based label propagation deep semisupervised learning (TSLP-SSL) method for sea ice classification based on…”
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6
Gadolinium Distribution in Cerebrospinal Fluid after Administration of a Gadolinium-based MR Contrast Agent in Humans
Published in Radiology (01-09-2018)“…Purpose To evaluate whether gadolinium penetrates human cerebrospinal fluid (CSF) after MR imaging (MRI) with a gadolinium-based contrast agent (GBCA)…”
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Occurrence and geochemistry of radium in water from principal drinking-water aquifer systems of the United States
Published in Applied geochemistry (01-03-2012)“…► 226Ra plus 228Ra exceed 0.185Bq/L in seven eastern and central USA principal aquifers. ► Radium concentration was highest in low pH and anoxic waters. ►…”
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(Un)targeted hair metabolomics: first considerations and systematic evaluation on the impact of sample preparation
Published in Analytical and bioanalytical chemistry (01-07-2019)“…The interest in metabolomic studies has rapidly increased over the past few years. Changes of endogenous compounds are typically detected in plasma or urine…”
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9
Single Hair Cocaine Consumption Monitoring by Mass Spectrometric Imaging
Published in Analytical chemistry (Washington) (01-06-2011)“…Matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) was used to image the distribution of cocaine and its metabolites in intact…”
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10
Single Hair Analysis of Small Molecules Using MALDI-Triple Quadrupole MS Imaging and LC-MS/MS: Investigations on Opportunities and Pitfalls
Published in Analytical chemistry (Washington) (02-12-2014)“…Single hair analysis normally requires extensive sample preparation microscale protocols including time-consuming steps like segmentation and extraction…”
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11
Endocannabinoid and steroid analysis in infant and adult nails by LC–MS/MS
Published in Analytical and bioanalytical chemistry (01-08-2022)“…A common method to quantify chronic stress is the analysis of stress markers in keratinized matrices such as hair or nail. In this study, we aimed to validate…”
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12
Studies on the metabolism of the fentanyl‐derived designer drug butyrfentanyl in human in vitro liver preparations and authentic human samples using liquid chromatography‐high resolution mass spectrometry (LC‐HRMS)
Published in Drug testing and analysis (01-07-2017)“…Increasing numbers of new psychoactive substances (NPS) among them fentanyl derivatives has been reported by the European monitoring centre for drugs and drug…”
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13
Time-dependent postmortem redistribution of butyrfentanyl and its metabolites in blood and alternative matrices in a case of butyrfentanyl intoxication
Published in Forensic science international (01-09-2016)“…Highlights • Butyrfentanyl and its metabolites undergo time-dependent postmortem redistribution processes. • Butyrfentanyl metabolism differs from fentanyl and…”
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14
Urinary concentrations of GHB and its novel amino acid and carnitine conjugates following controlled GHB administration to humans
Published in Scientific reports (02-06-2023)“…Gamma-hydroxybutyrate (GHB) remains a challenging clinical/forensic toxicology drug. Its rapid elimination to endogenous levels mainly causes this. Especially…”
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15
Steroid profiling in nails using liquid chromatography-tandem mass spectrometry
Published in Steroids (01-12-2018)“…•An LC-MS/MS method was developed for the quantification of 12 steroid hormones in nails.•3 steroid hormones were detected in nails for the first time.•Six…”
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Detection and validated quantification of 21 benzodiazepines and 3 “z-drugs” in human hair by LC–MS/MS
Published in Forensic science international (10-02-2012)“…Abstract A method for detection and quantification of 21 benzodiazepines and the pharmacologically related “z-drugs” in human hair samples was developed and…”
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17
Systematic assessment of different solvents for the extraction of drugs of abuse and pharmaceuticals from an authentic hair pool
Published in Forensic science international (01-01-2018)“…•Extraction solvent has a strong impact on hair analysis outcomes.•Acetonitrile alone is not recommended for drug extraction from hair.•Extraction efficiency…”
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Hair Analysis: Contamination versus Incorporation from the Circulatory SystemInvestigations on Single Hair Samples Using Time-of-Flight Secondary Ion Mass Spectrometry and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
Published in Analytical chemistry (Washington) (19-03-2019)“…Contamination is a highly controversial issue in hair analysis. Therefore, hair testing protocols typically include wash steps to remove contamination…”
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The renin‐angiotensin‐aldosterone system, neurohumoral axis and cardiovascular mortality in LURIC
Published in The journal of clinical hypertension (Greenwich, Conn.) (01-12-2022)“…Although neurohormones and Renin‐Angiotensin‐Aldosterone‐System (RAAS) components are important predictors of cardiovascular mortality (CVM), their importance…”
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Metabolomics-based Sleepiness Markers for Risk Prevention and Traffic Safety (ME-SMART): a monocentric, controlled, randomized, crossover trial
Published in Current controlled trials in cardiovascular medicine (21-02-2023)“…Too little sleep and the consequences thereof are a heavy burden in modern societies. In contrast to alcohol or illicit drug use, there are no quick roadside…”
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