Search Results - "Krackhardt, A"

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    Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells by Klar, R, Schober, S, Rami, M, Mall, S, Merl, J, Hauck, S M, Ueffing, M, Admon, A, Slotta-Huspenina, J, Schwaiger, M, Stevanović, S, Oostendorp, R A J, Busch, D H, Peschel, C, Krackhardt, A M

    Published in Leukemia (01-12-2014)
    “…T cells have been proven to be therapeutically effective in patients with relapsed leukemias, although target antigens on leukemic cells as well as T-cell…”
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    Journal Article
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    Transgenic antigen-specific, HLA-A02:01-allo-restricted cytotoxic T cells recognize and kill tumor associated antigen STEAP1+ tumour cells in vivo by Schirmer, D, Grünewald, T, Klar, R, Schmidt, O, Wohlleber, D, Alba Rubío, R, Uckert, W, Thiel, U, Protzer, U, Busch, D, Krackhardt, A, Burdach, S, Richter, G

    Published in European journal of cancer (1990) (01-12-2016)
    “…Background: Paediatric cancers, including Ewing sarcoma (ES), are only weakly immunogenic and the tumour-patients immune system often is devoid of effector T…”
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    P69. Targeting naturally presented, leukemia-derived HLA ligands with TCR-transgenic T cells for the treatment of therapy refractory leukemias by Richard, K, Schober, S, Rami, M, Mall, S, Merl, J, Slotta-Huspenina, J, Stevanovic, S, Busch, DH, Peschel, C, Krackhardt, AM

    Published in Journal for immunotherapy of cancer (12-03-2014)
    “…BackgroundT cells have proven to be effective for the treatment of leukaemias in form of donor lymphocyte infusions (DLI). However, those DLI are of unknown…”
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    Induction of cytotoxic T-cell responses against immunoglobulin V region–derived peptides modified at human leukocyte antigen–A2 binding residues by Harig, Sabine, Witzens, Mathias, Krackhardt, Angela M., Trojan, Andreas, Barrett, Patrick, Broderick, Ryan, Zauls, A. Jason, Gribben, John G.

    Published in Blood (15-11-2001)
    “…Cytotoxic T-lymphocyte (CTL) responses can be generated against peptides derived from the immunoglobulin (Ig) V region in some but not all patients. The main…”
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    P09.17 High-resolution of neoantigen-specific T cell receptor activation patterns – moderate stimulation predicts sustained anti-tumor-response by Füchsl, F, Untch, J, Kavaka, V, Jarosch, S, Vogelsang, C, de Andrade Krätzig, N, Gosmann, D, Rad, R, Busch, D, Beltran, E, Bräunlein, E, Krackhardt, A

    Published in Journal for immunotherapy of cancer (21-09-2022)
    “…BackgroundNeoantigen-specific T cell receptors (neoTCRs) increasingly receive attention for anti-tumor immunotherapy. Arising from somatic mutations and…”
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    P70. Development of clinically implementable imaging strategies for tracking T cell receptor-transgenic T cells by Mall, S, D'Alessandria, C, Aichler, M, Walch, A, Essler, M, Schwaiger, M, Peschel, C, Krackhardt, A

    Published in Journal for immunotherapy of cancer (12-03-2014)
    “…Transfer of T lymphocytes genetically modified with T-cell receptors (TCR) specific for tumour-associated antigens is a novel therapeutic approach for diverse…”
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    P73. Functional characterisation of HBV-specific T cell receptors for redirection of T cells against HBV infected hepatocytes by Krebs, K, Metzger, K, Weigand, L, Dargel, C, Kieback, E, Uckert, W, Busch, D, Krackhardt, A, Protzer, U

    Published in Journal for immunotherapy of cancer (12-03-2014)
    “…Chronic HBV infection, which is accompanied by a weak and oligoclonal T cell response, is the most common cause of hepatocellular carcinoma (HCC). Current…”
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