Search Results - "Krackhardt, A"
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Combined PET/MRI: Global Warming—Summary Report of the 6th International Workshop on PET/MRI, March 27–29, 2017, Tübingen, Germany
Published in Molecular imaging and biology (01-02-2018)“…The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again in Tübingen, Germany, from…”
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Hepatitis B virus-specific T cell receptors with high functional avidity redirect T cells to eliminate HBV
Published in Journal of hepatology (2017)Get full text
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Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells
Published in Leukemia (01-12-2014)“…T cells have been proven to be therapeutically effective in patients with relapsed leukemias, although target antigens on leukemic cells as well as T-cell…”
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Transgenic antigen-specific, HLA-A02:01-allo-restricted cytotoxic T cells recognize and kill tumor associated antigen STEAP1+ tumour cells in vivo
Published in European journal of cancer (1990) (01-12-2016)“…Background: Paediatric cancers, including Ewing sarcoma (ES), are only weakly immunogenic and the tumour-patients immune system often is devoid of effector T…”
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Selective Depletion of Alloreactive T-cells While Retaining Virus-specific and Memory T-cells from Haploidentical Donor Lymphocytes
Published in Cytotherapy (Oxford, England) (01-06-2016)Get full text
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Functional Characterization of HBV-Specific T Cell Receptors for Redirection of T Cells Against HBV-Infected Hepatocytes
Published in Cytotherapy (Oxford, England) (01-06-2016)Get full text
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P69. Targeting naturally presented, leukemia-derived HLA ligands with TCR-transgenic T cells for the treatment of therapy refractory leukemias
Published in Journal for immunotherapy of cancer (12-03-2014)“…BackgroundT cells have proven to be effective for the treatment of leukaemias in form of donor lymphocyte infusions (DLI). However, those DLI are of unknown…”
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Induction of cytotoxic T-cell responses against immunoglobulin V region–derived peptides modified at human leukocyte antigen–A2 binding residues
Published in Blood (15-11-2001)“…Cytotoxic T-lymphocyte (CTL) responses can be generated against peptides derived from the immunoglobulin (Ig) V region in some but not all patients. The main…”
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Generation of cytotoxic T lymphocytes against native and altered peptides of human leukocyte antigen-A0201 restricted epitopes from the human epithelial cell adhesion molecule
Published in Cancer research (Chicago, Ill.) (15-06-2001)“…A growing number of human tumor antigens have been described that can be recognized by CTLs in a MHC class I restricted fashion. The epithelial cell adhesion…”
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T cells grafted with HBV-specific T-cell receptors of high functional avidity achieve functional cure of HBV infection in humanized mice
Published in Journal of hepatology (01-04-2018)Get full text
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Activation of autologous lymphocytes of patients with chronic myelogenous leukemia in the chronic phase with cytokines and CD3 monoclonal antibody results in bcr/abl- blood leukocyte cultures as determined by reverse transcriptase-polymerase chain reaction
Published in Experimental hematology (01-12-1998)“…To investigate the potential of autologous lymphocytes to eliminate chronic myelogenous leukemia (CML) cells following activation and targeting by…”
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PS-051 - Hepatitis B virus-specific T cell receptors with high functional avidity redirect T cells to eliminate HBV
Published in Journal of hepatology (2017)Get full text
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P09.17 High-resolution of neoantigen-specific T cell receptor activation patterns – moderate stimulation predicts sustained anti-tumor-response
Published in Journal for immunotherapy of cancer (21-09-2022)“…BackgroundNeoantigen-specific T cell receptors (neoTCRs) increasingly receive attention for anti-tumor immunotherapy. Arising from somatic mutations and…”
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27 - Functional Characterization of HBV-Specific T Cell Receptors for Redirection of T Cells Against HBV-Infected Hepatocytes
Published in Cytotherapy (Oxford, England) (01-06-2016)Get full text
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P70. Development of clinically implementable imaging strategies for tracking T cell receptor-transgenic T cells
Published in Journal for immunotherapy of cancer (12-03-2014)“…Transfer of T lymphocytes genetically modified with T-cell receptors (TCR) specific for tumour-associated antigens is a novel therapeutic approach for diverse…”
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P73. Functional characterisation of HBV-specific T cell receptors for redirection of T cells against HBV infected hepatocytes
Published in Journal for immunotherapy of cancer (12-03-2014)“…Chronic HBV infection, which is accompanied by a weak and oligoclonal T cell response, is the most common cause of hepatocellular carcinoma (HCC). Current…”
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