Search Results - "Kracikova, M"

A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis by Kracikova, M, Akiri, G, George, A, Sachidanandam, R, Aaronson, S A

“…The p53 tumor suppressor responds to certain cellular stresses by inducing transcriptional programs that can lead to growth arrest or apoptosis. However, the…”
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p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes by Benson, E K, Mungamuri, S K, Attie, O, Kracikova, M, Sachidanandam, R, Manfredi, J J, Aaronson, S A

“…The p53 tumor suppressor protein is a major sensor of cellular stresses, and upon stabilization, activates or represses many genes that control cell fate…”
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