Search Results - "Krčová, Lucie"
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Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders
Published in Scientific reports (26-09-2018)“…The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable…”
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Highly selective mitochondrial probes based on fluorinated pentamethinium salts: On two-photon properties and microscopic applications
Published in Dyes and pigments (01-01-2020)“…Fluorescent dyes and probes have been of interest in the fields of chemistry and biology for a long time. However, with more recent applications in advanced…”
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Coumarin Tröger’s base derivatives with cyanine substitution as selective and sensitive fluorescent lysosomal probes
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] •Fluorescent lysosomal probes based on a Tröger's base skeleton.•Synergically utilize three properties in one structure: native basicity,…”
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Combination of quinoxaline with pentamethinium system: Mitochondrial staining and targeting
Published in Bioorganic chemistry (01-12-2023)“…[Display omitted] •Quinoxaline conjugates with indolium PMS were prepared and full characterized.•Strong affinity and fluorescence response against…”
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A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse
Published in International journal of molecular sciences (28-08-2019)“…Cancer cells preferentially utilize glycolysis for ATP production even in aerobic conditions (the Warburg effect) and adapt mitochondrial processes to their…”
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