Search Results - "Krämer, Chiara"

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy by Grosch, Markus, Schraft, Laura, Chan, Adrian, Küchenhoff, Leonie, Rapti, Kleopatra, Ferreira, Anne-Maud, Kornienko, Julia, Li, Shengdi, Radke, Michael H., Krämer, Chiara, Clauder-Münster, Sandra, Perlas, Emerald, Backs, Johannes, Gotthardt, Michael, Dieterich, Christoph, van den Hoogenhof, Maarten M. G., Grimm, Dirk, Steinmetz, Lars M.

“…Dilated cardiomyopathy is the second most common cause for heart failure with no cure except a high-risk heart transplantation. Approximately 30% of patients…”
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Lab-Scale Production of Recombinant Adeno-Associated Viruses (AAV) for Expression of Optogenetic Elements by Haar, Janina, Krämer, Chiara, Grimm, Dirk

“…Optogenetics, that is, the use of photoswitchable/-activatable moieties to precisely control or monitor the activity of cells and genes at unprecedented…”
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Relevance of Assembly-Activating Protein for Adeno-associated Virus Vector Production and Capsid Protein Stability in Mammalian and Insect Cells by Grosse, Stefanie, Penaud-Budloo, Magalie, Herrmann, Anne-Kathrin, Börner, Kathleen, Fakhiri, Julia, Laketa, Vibor, Krämer, Chiara, Wiedtke, Ellen, Gunkel, Manuel, Ménard, Lucie, Ayuso, Eduard, Grimm, Dirk

“…The discovery that adeno-associated virus 2 (AAV2) encodes an eighth protein, called assembly-activating protein (AAP), transformed our understanding of…”
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Impact of the Assembly-Activating Protein on Molecular Evolution of Synthetic Adeno-Associated Virus Capsids by Herrmann, Anne-Kathrin, Große, Stefanie, Börner, Kathleen, Krämer, Chiara, Wiedtke, Ellen, Gunkel, Manuel, Grimm, Dirk

“…Over the last decade, the role of the assembly-activating protein (AAP) has begun to be dissected for the formation of adeno-associated virus (AAV) capsids…”
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Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders by El Andari, Jihad, Renaud-Gabardos, Edith, Tulalamba, Warut, Weinmann, Jonas, Mangin, Louise, Pham, Quang Hong, Hille, Susanne, Bennett, Antonette, Attebi, Esther, Bourges, Emanuele, Leborgne, Christian, Guerchet, Nicolas, Fakhiri, Julia, Krämer, Chiara, Wiedtke, Ellen, McKenna, Robert, Guianvarc’h, Laurence, Toueille, Magali, Ronzitti, Giuseppe, Hebben, Matthias, Mingozzi, Federico, VandenDriessche, Thierry, Agbandje-McKenna, Mavis, Müller, Oliver J., Chuah, Marinee K., Buj-Bello, Ana, Grimm, Dirk

“…Bioengineering of viral vectors for therapeutic gene delivery is a pivotal strategy to reduce doses, facilitate manufacturing, and improve efficacy and patient…”
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