Search Results - "Královec, Karel"

Chemical Composition of Natural Hydrolates and Their Antimicrobial Activity on Arcobacter -Like Cells in Comparison with Other Microorganisms by Šilha, David, Švarcová, Karolína, Bajer, Tomáš, Královec, Karel, Tesařová, Eliška, Moučková, Kristýna, Pejchalová, Marcela, Bajerová, Petra

“…Hydrolates obtained via the hydrodistillation and steam distillation of Mill., L., Mill., and L. were analyzed by gas chromatography with flame ionization…”
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Disruption of Cell Adhesion and Cytoskeletal Networks by Thiol-Functionalized Silica-Coated Iron Oxide Nanoparticles by Královec, Karel, Melounková, Lucie, Slováková, Marcela, Mannová, Nikola, Sedlák, Miloš, Bartáček, Jan, Havelek, Radim

“…One of the major obstacles that limits the use of magnetic nanoparticles in biomedical applications is their potential toxicity. In the present study, we…”
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Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells by Koutová, Darja, Havelek, Radim, Peterová, Eva, Muthná, Darina, Královec, Karel, Breiterová, Kateřina, Cahlíková, Lucie, Řezáčová, Martina

“…Pancracine, a montanine-type Amaryllidaceae alkaloid (AA), is one of the most potent compounds among natural isoquinolines. In previous studies, pancracine…”
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Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells by Koutova, Darja, Kulhava, Monika, Havelek, Radim, Majorosova, Martina, Královec, Karel, Habartova, Klara, Hošťálková, Anna, Opletal, Lubomír, Cahlikova, Lucie, Řezáčová, Martina

“…Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L. (Berberidaceae) plant. The results of cytotoxicity screening 48 h…”
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Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities by Ritomská, Aneta, Koutova, Darja, Křoustková, Jana, Královec, Karel, Muthná, Darina, Kuneš, Jiří, Nováková, Lucie, Havelek, Radim, Cahlíková, Lucie

“…Ambelline, an alkaloid from the Amaryllidaceae family with a crinane-type skeleton, has not yet demonstrated any outstanding biological activity. However, its…”
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Rod-like particles of silica-coated maghemite: Synthesis via akaganeite, characterization and biological properties by Veverka, Pavel, Pashchenko, Mariia, Kubíčková, Lenka, Kuličková, Jarmila, Jirák, Zdeněk, Havelek, Radim, Královec, Karel, Kohout, Jaroslav, Kaman, Ondřej

“…•Rod-like maghemite particles were prepared by using an akaganeite precursor.•The oxidation state of Fe was unambiguously determined by Mössbauer…”
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Magnetic nanoparticles of Ga‐substituted ε‐Fe2O3 for biomedical applications: Magnetic properties, transverse relaxivity, and effects of silica‐coated particles on cytoskeletal networks by Královec, Karel, Havelek, Radim, Koutová, Darja, Veverka, Pavel, Kubíčková, Lenka, Brázda, Petr, Kohout, Jaroslav, Herynek, Vít, Vosmanská, Magda, Kaman, Ondřej

“…Magnetic nanoparticles of ε‐Fe1.76Ga0.24O3 with the volume‐weighted mean size of 17 nm were prepared by thermal treatment of a mesoporous silica template…”
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Magnetic oxide particles with gold nanoshells: Synthesis, properties and cytotoxic effects by Koktan, Jakub, Královec, Karel, Havelek, Radim, Kuličková, Jarmila, Řezanka, Pavel, Kaman, Ondřej

“…[Display omitted] •Gold nanoshells are formed around superparamagnetic Mn-Zn ferrite with silica.•The product shows low cytotoxic effects and efficient…”
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Silica coated iron oxide nanoparticles-induced cytotoxicity, genotoxicity and its underlying mechanism in human HK-2 renal proximal tubule epithelial cells by Královec, Karel, Havelek, Radim, Kročová, Eliška, Kučírková, Lucie, Hauschke, Martina, Bartáček, Jan, Palarčík, Jiří, Sedlák, Miloš

“…•Silica coated IONPs exhibited cytotoxic and genotoxic effects against HK-2 cells.•Exposure to silica coated IONPs induced DNA double-strand breaks.•Treatment…”
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Mn-Zn Ferrite Nanoparticles With Silica and Titania Coatings: Synthesis, Transverse Relaxivity, and Cytotoxicity by Kaman, Ondrej, Kulickova, Jarmila, Marysko, Miroslav, Veverka, Pavel, Herynek, Vit, Havelek, Radim, Kralovec, Karel, Kubaniova, Denisa, Kohout, Jaroslav, Dvorak, Petr, Jirak, Zdenek

“…Mn-Zn ferrite nanoparticles of composition Mn 0,61 Zn 0,42 Fe 1,97 O 4 and mean size of crystallites d XRD = 11 nm are synthesized under hydrothermal…”
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Albumin-coated monodisperse magnetic poly(glycidyl methacrylate) microspheres with immobilized antibodies: Application to the capture of epithelial cancer cells by Horák, Daniel, Svobodová, Zuzana, Autebert, Julien, Coudert, Benoit, Plichta, Zdeněk, Královec, Karel, Bílková, Zuzana, Viovy, Jean-Louis

“…Monodisperse (4 μm) macroporous crosslinked poly(glycidyl methacrylate) (PGMA) microspheres for use in microfluidic immunomagnetic cell sorting, with a…”
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Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors by Pejchal, Vladimír, Štěpánková, Šárka, Pejchalová, Marcela, Královec, Karel, Havelek, Radim, Růžičková, Zdeňka, Ajani, Haresh, Lo, Rabindranath, Lepšík, Martin

“…[Display omitted] In the current study, sixteen novel derivatives of (R)-1-(6-fluorobenzo[d]thiazol-2-yl)ethanamine were synthesized as acetylcholinesterase…”
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Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores by Bui, Duong Thuy, Havelek, Radim, Královec, Karel, Kubíčková, Lenka, Kuličková, Jarmila, Matouš, Petr, Herynek, Vít, Kupčík, Jaroslav, Muthná, Darina, Řezanka, Pavel, Kaman, Ondřej

“…Highly complex nanoparticles combining multimodal imaging with the sensing of physical properties in biological systems can considerably enhance biomedical…”
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Cytotoxic activities of Amaryllidaceae alkaloids against gastrointestinal cancer cells by Doskočil, Ivo, Hošťálková, Anna, Šafratová, Marcela, Benešová, Nina, Havlík, Jaroslav, Havelek, Radim, Kuneš, Jiří, Královec, Karel, Chlebek, Jakub, Cahlíková, Lucie

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Novel derivatives of substituted 6-fluorobenzothiazole diamides: synthesis, antifungal activity and cytotoxicity by Pejchalová, Marcela, Havelek, Radim, Královec, Karel, Růžičková, Zdeňka, Pejchal, Vladimír

“…A new series of 1-[(1 R )-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-substituted phenyl diamides were synthesized in vitro as potential antifungal agents…”
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Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors by Imramovský, Aleš, Pejchal, Vladimír, Štěpánková, Šárka, Vorčáková, Katarína, Jampílek, Josef, Vančo, Ján, Šimůnek, Petr, Královec, Karel, Brůčková, Lenka, Mandíková, Jana, Trejtnar, František

“…A series of novel cholinesterase inhibitors based on 2-substituted 6-fluorobenzo[d]thiazole were synthesised and characterised by IR, 1H, 13C and 19F NMR…”
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Silica-coated manganite and Mn-based ferrite nanoparticles: a comparative study focused on cytotoxicity by Kaman, Ondřej, Dědourková, Tereza, Koktan, Jakub, Kuličková, Jarmila, Maryško, Miroslav, Veverka, Pavel, Havelek, Radim, Královec, Karel, Turnovcová, Karolína, Jendelová, Pavla, Schröfel, Adam, Svoboda, Ladislav

“…Magnetic oxide nanoparticles provide a fascinating tool for biological research and medicine, serving as contrast agents, magnetic carriers, and core materials…”
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Synthesis, characterization and in vitro evaluation of substituted N-(2-phenylcyclopropyl)carbamates as acetyl- and butyrylcholinesterase inhibitors by Horáková, Eva, Drabina, Pavel, Brož, Břetislav, Štěpánková, Šárka, Vorčáková, Katarína, Královec, Karel, Havelek, Radim, Sedlák, Miloš

“…A serie of O-substituted N-2-phenylcyclopropylcarbamates was prepared and characterized. These carbamates were tested as inhibitors of acetylcholinesterase…”
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Synthesis and characterization of a pH-sensitive conjugate of isoniazid with Fe3O4@SiO2 magnetic nanoparticles by Sedlák, Miloš, Bhosale, Dattatry Shivajirao, Beneš, Ludvík, Palarčík, Jiří, Kalendová, Andrea, Královec, Karel, Imramovský, Aleš

“…The Letter describes the preparation and characterization of a conjugate of isoniazid (INH) with magnetic nanoparticles Fe3O4@SiO2 115±60nm in size. The INH…”
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Development of the olfactory and vomeronasal organs in Discoglossus pictus (Discoglossidae, Anura) by Kralovec, Karel, akova, Pavla, Muzakova, Vladimira

“…Using histological techniques and computer‐aided three‐dimensional reconstructions of histological serial sections, we studied the development of the olfactory…”
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