Search Results - "Kozyreva, Varvara K"
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A hybridization target enrichment approach for pathogen genomics
Published in mBio (31-10-2023)“…Emerging infectious diseases require continuous pathogen monitoring. Rapid clinical diagnosis by nucleic acid amplification is limited to a small number of…”
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Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer
Published in Molecular cancer therapeutics (01-08-2016)“…Recent findings suggest that the inhibition of Aurora A (AURKA) kinase may offer a novel treatment strategy against metastatic cancers. In the current study,…”
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Bacterial Resistance Studies Using In Vitro Dynamic Models: the Predictive Power of the Mutant Prevention and Minimum Inhibitory Antibiotic Concentrations
Published in Antimicrobial Agents and Chemotherapy (01-10-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner
Published in Molecular cancer research (01-05-2014)“…The prometastatic protein NEDD9 (neural precursor cell expressed, developmentally downregulated 9) is highly expressed in many cancers and is required for…”
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Recent Outbreaks of Shigellosis in California Caused by Two Distinct Populations of Shigella sonnei with either Increased Virulence or Fluoroquinolone Resistance
Published in mSphere (01-11-2016)“…has caused unusually large outbreaks of shigellosis in California in 2014 and 2015. Preliminary data indicated the involvement of two distinct bacterial…”
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Validation and Implementation of Clinical Laboratory Improvements Act-Compliant Whole-Genome Sequencing in the Public Health Microbiology Laboratory
Published in Journal of clinical microbiology (01-08-2017)“…Public health microbiology laboratories (PHLs) are on the cusp of unprecedented improvements in pathogen identification, antibiotic resistance detection, and…”
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Convergent In Vivo and In Vitro Selection of Ceftazidime Resistance Mutations at Position 167 of CTX-M-3 β-Lactamase in Hypermutable Escherichia coli Strains
Published in Antimicrobial Agents and Chemotherapy (01-04-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior
Published in Molecular cancer research (01-06-2017)“…Commonly upregulated in human cancers, the scaffolding protein NEDD9/HEF1 is a known regulator of mesenchymal migration and cancer cell plasticity. However,…”
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Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins
Published in Molecular cancer research (01-03-2015)“…The dissemination of tumor cells relies on efficient cell adhesion and migration, which in turn depends upon endocytic trafficking of integrins. In the current…”
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Laboratory Investigation of Salmonella enterica serovar Poona Outbreak in California: Comparison of Pulsed-Field Gel Electrophoresis (PFGE) and Whole Genome Sequencing (WGS) Results
Published in PLoS currents (22-11-2016)“…Recently, serovar Poona caused a multistate outbreak, with 245 out of 907 cases occurring in California. We report a comparison of pulsed-field gel…”
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NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis
Published in Molecular cancer research (01-01-2014)“…The scaffolding protein NEDD9 is an established prometastatic marker in several cancers. Nevertheless, the molecular mechanisms of NEDD9-driven metastasis in…”
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Long-term dissemination of CTX-M-5-producing hypermutable Salmonella enterica serovar typhimurium sequence type 328 strains in Russia, Belarus, and Kazakhstan
Published in Antimicrobial agents and chemotherapy (01-09-2014)“…In this paper, we present evidence of long-term circulation of cefotaxime-resistant clonally related Salmonella enterica serovar Typhimurium strains over a…”
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NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer
Published in Oncogene (01-07-2015)“…NEDD9 is an established marker of invasive and metastatic cancers. NEDD9 downregulation has been shown to dramatically reduce cell invasion and metastasis in…”
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Abstract 4934: The role of Aurora A kinase-dependent phosphorylation of cortactin in invadopodia formation
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Aurora A kinase (AURKA) is a serine/threonine kinase known for its critical role in regulation of cell cycle progression. Overexpression and…”
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Pro-metastatic NEDD9 regulates individual cell migration via caveolin-1-dependent trafficking of integrins
Published in Molecular cancer research (15-10-2014)“…The dissemination of tumor cells relies on efficient cell adhesion and migration, which in turn depends upon endocytic trafficking of integrins. In the current…”
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Abstract B61: HEF1-dependent Aurora A kinase phosphorylation activates HDAC6
Published in Cancer research (Chicago, Ill.) (15-09-2011)“…Abstract Histone deacetylase 6 (HDAC6) is known to be important participant of many tumorgenesis processes including cytoskeleton rearrangement, cell migration…”
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