Search Results - "Kozyreva, Varvara"

Validation and Implementation of Clinical Laboratory Improvements Act-Compliant Whole-Genome Sequencing in the Public Health Microbiology Laboratory by Kozyreva, Varvara K, Truong, Chau-Linda, Greninger, Alexander L, Crandall, John, Mukhopadhyay, Rituparna, Chaturvedi, Vishnu

“…Public health microbiology laboratories (PHLs) are on the cusp of unprecedented improvements in pathogen identification, antibiotic resistance detection, and…”
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A hybridization target enrichment approach for pathogen genomics by Sundararaman, Balaji, Sylvester, Matthew D, Kozyreva, Varvara K, Berrada, Zenda L, Corbett-Detig, Russell B, Green, Richard E

“…Emerging infectious diseases require continuous pathogen monitoring. Rapid clinical diagnosis by nucleic acid amplification is limited to a small number of…”
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Editorial: Integration of NGS in clinical and public health microbiology workflows: applications, compliance, quality considerations by Yang, Shangxin, Kozyreva, Varvara K, Timme, Ruth E, Hemarajata, Peera

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Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer by Kozyreva, Varvara K, Kiseleva, Anna A, Ice, Ryan J, Jones, Brandon C, Loskutov, Yuriy V, Matalkah, Fatimah, Smolkin, Matthew B, Marinak, Kristina, Livengood, Ryan H, Salkeni, Mohamad A, Wen, Sijin, Hazard, Hannah W, Layne, Ginger P, Walsh, Callee M, Cantrell, Pamela S, Kilby, Greg W, Mahavadi, Sricharan, Shah, Neal, Pugacheva, Elena N

“…Recent findings suggest that the inhibition of Aurora A (AURKA) kinase may offer a novel treatment strategy against metastatic cancers. In the current study,…”
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Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior by Jones, Brandon C, Kelley, Laura C, Loskutov, Yuriy V, Marinak, Kristina M, Kozyreva, Varvara K, Smolkin, Matthew B, Pugacheva, Elena N

“…Commonly upregulated in human cancers, the scaffolding protein NEDD9/HEF1 is a known regulator of mesenchymal migration and cancer cell plasticity. However,…”
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Bacterial Resistance Studies Using In Vitro Dynamic Models: the Predictive Power of the Mutant Prevention and Minimum Inhibitory Antibiotic Concentrations by FIRSOV, Alexander A, STRUKOVA, Elena N, SHLYKOVA, Darya S, PORTNOY, Yury A, KOZYREVA, Varvara K, EDELSTEIN, Mikhail V, DOVZHENKO, Svetlana A, KOBRIN, Mikhail B, ZINNER, Stephen H

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner by Kozyreva, Varvara K, McLaughlin, Sarah L, Livengood, Ryan H, Calkins, Robin A, Kelley, Laura C, Rajulapati, Anuradha, Ice, Ryan J, Smolkin, Matthew B, Weed, Scott A, Pugacheva, Elena N

“…The prometastatic protein NEDD9 (neural precursor cell expressed, developmentally downregulated 9) is highly expressed in many cancers and is required for…”
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Recent Outbreaks of Shigellosis in California Caused by Two Distinct Populations of Shigella sonnei with either Increased Virulence or Fluoroquinolone Resistance by Kozyreva, Varvara K, Jospin, Guillaume, Greninger, Alexander L, Watt, James P, Eisen, Jonathan A, Chaturvedi, Vishnu

“…has caused unusually large outbreaks of shigellosis in California in 2014 and 2015. Preliminary data indicated the involvement of two distinct bacterial…”
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Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins by Kozyulina, Polina Y, Loskutov, Yuriy V, Kozyreva, Varvara K, Rajulapati, Anuradha, Ice, Ryan J, Jones, Brandon C, Pugacheva, Elena N

“…The dissemination of tumor cells relies on efficient cell adhesion and migration, which in turn depends upon endocytic trafficking of integrins. In the current…”
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Laboratory Investigation of Salmonella enterica serovar Poona Outbreak in California: Comparison of Pulsed-Field Gel Electrophoresis (PFGE) and Whole Genome Sequencing (WGS) Results by Kozyreva, Varvara K, Crandall, John, Sabol, Ashley, Poe, Alyssa, Zhang, Peng, Concepción-Acevedo, Jeniffer, Schroeder, Morgan N, Wagner, Darlene, Higa, Jeffrey, Trees, Eija, Chaturvedi, Vishnu

“…Recently, serovar Poona caused a multistate outbreak, with 245 out of 907 cases occurring in California. We report a comparison of pulsed-field gel…”
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NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis by McLaughlin, Sarah L, Ice, Ryan J, Rajulapati, Anuradha, Kozyulina, Polina Y, Livengood, Ryan H, Kozyreva, Varvara K, Loskutov, Yuriy V, Culp, Mark V, Weed, Scott A, Ivanov, Alexey V, Pugacheva, Elena N

“…The scaffolding protein NEDD9 is an established prometastatic marker in several cancers. Nevertheless, the molecular mechanisms of NEDD9-driven metastasis in…”
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Long-term dissemination of CTX-M-5-producing hypermutable Salmonella enterica serovar typhimurium sequence type 328 strains in Russia, Belarus, and Kazakhstan by Kozyreva, Varvara K, Ilina, Elena N, Malakhova, Maja V, Carattoli, Alessandra, Azizov, Ilya S, Tapalski, Dmitry V, Kozlov, Roman S, Edelstein, Mikhail V

“…In this paper, we present evidence of long-term circulation of cefotaxime-resistant clonally related Salmonella enterica serovar Typhimurium strains over a…”
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Convergent In Vivo and In Vitro Selection of Ceftazidime Resistance Mutations at Position 167 of CTX-M-3 β-Lactamase in Hypermutable Escherichia coli Strains by STEPANOVA, Marina N, PIMKIN, Maxim, NIKULIN, Anatoly A, KOZYREVA, Varvara K, AGAPOVA, Elena D, EDELSTEIN, Mikhail V

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Draft Genome Sequence of Kerstersia gyiorum CG1, Isolated from a Leg Ulcer by Greninger, Alexander L, Kozyreva, Varvara, Truong, Chau-Linda, Longoria, Rose, Chaturvedi, Vishnu

“…We report the first draft genome sequence of Kerstersia gyiorum from a leg ulcer of a patient with diabetes and osteomyelitis. The 3.94-Mb genome assembly…”
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Abstract 1084: Combination of eribulin and AURKA inhibitor prevents metastatic colonization and eradicates established metastases in breast cancer by Pugacheva, Elena N., Kozyreva, Varvara, Kiseleva, Anna, Ice, Ryan, Jones, Brandon, Loskutov, Yuriy

“…The majority of cancer-related deaths (90%) are happened due to metastasis from the primary tumor site to distant organs. MLN8237 is a small, highly selective…”
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NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer by Loskutov, Y V, Kozyulina, P Y, Kozyreva, V K, Ice, R J, Jones, B C, Roston, T J, Smolkin, M B, Ivanov, A V, Wysolmerski, R B, Pugacheva, E N

“…NEDD9 is an established marker of invasive and metastatic cancers. NEDD9 downregulation has been shown to dramatically reduce cell invasion and metastasis in…”
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Abstract 4934: The role of Aurora A kinase-dependent phosphorylation of cortactin in invadopodia formation by Kozyreva, Varvara K., Kelley, Laura, McLaughlin, Sarah L., Pugacheva, Elena N.

“…Aurora A kinase (AURKA) is a serine/threonine kinase known for its critical role in regulation of cell cycle progression. Overexpression and activation of…”
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Pro-metastatic NEDD9 regulates individual cell migration via caveolin-1-dependent trafficking of integrins by Kozyulina, Polina Y., Loskutov, Yuriy V., Kozyreva, Varvara K., Rajulapati, Anuradha, Ice, Ryan J., Jones, Brandon. C., Pugacheva, Elena N.

“…The dissemination of tumor cells relies on efficient cell adhesion and migration, which in turn depends upon endocytic trafficking of integrins. In the current…”
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Abstract 2013: NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis by Pugacheva, Elena N., McLaughlin, Sarah, Ice, Ryan, Rajulapati, Anuradha, Kozyulina, Polina, Livengood, Ryan, Kozyreva, Varvara, Loskutov, Yuriy, Ivanov, Alexey, Weed, Scott

“…The scaffolding protein NEDD9 is an established pro-metastatic marker in several cancers. Nevertheless, the molecular mechanisms of NEDD9 driven metastasis in…”
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Abstract B61: HEF1-dependent Aurora A kinase phosphorylation activates HDAC6 by Kozyreva, Varvara K., McLaughlin, Sarah L., Kelley, Laura, Pugacheva, Elena N.

“…Histone deacetylase 6 (HDAC6) is known to be important participant of many tumorgenesis processes including cytoskeleton rearrangement, cell migration and…”
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