Search Results - "Kozurkova, M."

Lichen secondary metabolites as DNA-interacting agents by Plsíkova, J., Stepankova, J., Kasparkova, J., Brabec, V., Backor, M., Kozurkova, M.

“…•Interactions of selected lichen secondary metabolites 1–4 with calf thymus DNA were studied.•Binding constants of 4.3×105–2.4×107M−1 were determined from…”
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Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity by Janockova, J, Zilecka, E, Kasparkova, J, Brabec, V, Soukup, O, Kuca, K, Kozurkova, M

“…In this paper, we describe the biochemical properties and biological activity of a series of cholinesterase reactivators (symmetrical bisquaternary…”
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DNA binding, anti-tumour activity and reactivity toward cell thiols of acridin-9-ylalkenoic derivatives by SALEM, O, VILKOVA, M, PLSIKOVA, J, GROLMUSOVA, A, BURIKOVA, M, PROKAIOVA, M, PAULIKOVA, H, IMRICH, J, KOZURKOVA, M

“…In this paper, we describe the synthesis, biochemical properties and biological activity of a series of new 9-substituted acridine derivatives with a reactive…”
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DNA-protective activities of hyperforin and aristoforin by Ševčovičová, A., Šemeláková, M., Plšíková, J., Loderer, D., Imreová, P., Gálová, E., Kožurková, M., Miadoková, E., Fedoročko, P.

“…•Mechanisms of hyperforin and aristoforin DNA-protective activities were studied in vitro.•Both chemicals protect DNA against Fe2+-induced DNA…”
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Interaction of a copper(II)–Schiff base complexes with calf thymus DNA and their antimicrobial activity by Sabolová, D., Kožurková, M., Plichta, T., Ondrušová, Z., Hudecová, D., Šimkovič, M., Paulíková, H., Valent, A.

“…The interaction of a copper complexes containing Schiff bases with calf thymus (CT) DNA was investigated by spectroscopic methods. UV–vis, fluorescence and CD…”
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DNA binding properties and evaluation of cytotoxic activity of 9,10-bis- N-substituted (aminomethyl)anthracenes by Kožurková, M., Sabolová, D., Paulíková, H., Janovec, L., Kristian, P., Bajdichová, M., Buša, J., Podhradský, D., Imrich, Ján

“…The results of DNA binding properties for four selected N-substituted 9,10-bis(aminomethyl)anthracenes are presented. DNA binding affinities were studied using…”
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Study of DNA interactions with cyclic chalcone derivatives by spectroscopic techniques by Štefanišinová, M., Tomečková, V., Kožurková, M., Ostró, A., Mareková, M.

“…The interaction between these ligands and calf thymus DNA was studied with UV–vis, fluorescence in addition to circular dichroism spectroscopy. The binding…”
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Determination of the binding affinities of plasmid DNA using fluorescent intercalators possessing an acridine skeleton by Sabolová, D., Kožurková, M., Kristian, P., Danihel, I., Podhradský, D., Imrich, J.

“…Novel acridine derivatives, wherein the steric factor has been varied systematically through substitution at the 9 position of the acridine ring, were…”
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Aging and radiation induced alterations of histones in regenerating rat liver by Kozurková, M, Misúrová, E, Kropácová, K

“…We studied the age-related and radiation-induced changes in histones in regenerating liver of rats between 1 and 28 months of age. The examinations were…”
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Effect of aging and gamma radiation on acetylation of rat liver histones by KOZURKOVA, M, MISUROVA, E, KROPACOVA, K

“…We studied age-related and radiation induced changes in histone acetyltransferase activity and acetylation of histone fractions in normal and regenerating rat…”
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Aging and radiation induced alterations in liver histones by KOZURKOVA, M, MISUROVA, E, KROPACOVA, K

“…Age-related changes in histones in the liver of normal rats and in rats irradiated with 5.7 Gy gamma rays were examined. Quantitative histone changes in…”
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Influence of Gamma Irradiation on DNA Methylation in Liver of Male Rats and their Offspring by Kozurkova, M, Letavayova, L, Misurova, E

“…In the present work, the influence of gamma radiation (3 Gy) on DNA methylation in slowly proliferating liver tissue of adult male rats and their offspring was…”
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Effect of hepatoprotective agents thioctacid and flavobion on histones in the intact and regenerating liver of irradiated rats by Kožurkova, M., Kropačova, K., Mišurova, E., Rexa, R.

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Synthesis, DNA Interaction, and Cytotoxic Activity of a Novel Proflavine−Dithiazolidinone Pharmacophore by Janovec, Ladislav, Sabolová, Danica, Kožurková, Mária, Paulíková, Helena, Kristian, Pavol, Ungvarský, Ján, Moravčíková, Erika, Bajdichová, Mária, Podhradský, Dušan, Imrich, Ján

“…Five novel proflavine−dithiazolidinone derivatives 4a−4e have been designed and synthesized by the reaction of dialkyl acridin-3,6-diyl dithioureas 3a−3e with…”
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The effect of essentiale on histones and nucleic acids in liver and blood-forming tissues of rats irradiated with gamma-rays by Kozurková, M, Misúrová, E, Kropácová, K, Haková, H

“…In this paper, the influence of the hepatoprotective drug Essentiale on the target (normal and regenerating liver) and the non-target (spleen and bone marrow)…”
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Changes in liver histones in rats after single, continuous and combined irradiation with gamma rays by Kozurková, M, Misúrová, E

“…The authors examined the concentration and total contents of histones and the relative ratio of different fractions of histones in the liver of rats after a…”
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The effect of silymarin, a hepatoprotective substance, on liver histones in irradiated rats by Kozurková, M, Haková, H, Misúrová, E

“…Changes of concentration, total content of histones and relative portions of histone fractions were investigated in the liver of rats after administration of…”
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